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Biomonitoring of Platinum Group Elements (PGEs) in Occupational Medicine

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Platinum Metals in the Environment

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Abstract

Platinum, palladium, rhodium and iridium are platinum group elements (PGEs) employed in several industrial, chemical, and electronic applications and as active catalyst materials in automotive converters. However, despite the widespread use of these metals and their increasing emission into the environment due to the abrasion of catalytic devices, little is known of their toxic effects. Considerable concern has therefore arisen over the potential health risks for the general population and particularly for workers exposed to PGEs during production and recycling activities or via traffic emissions. Consequently, biological monitoring is important in order to assess PGE exposure, early effects and susceptibility factors so that occupational risks can be adequately evaluated and managed. This chapter aims to evaluate potential biomarkers of occupational PGE exposure and discuss issues regarding future research aimed at determining indicators of early PGE effects and susceptibility, and focus on the relevance and feasibility of these potential biomarkers in occupational health practice.

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References

  • Baker DB, Gann PH, Brooks SM, Gallagher J, Bernstein IL (1990) Cross-sectional study of platinum salts sensitization among precious metals refinery workers. Am J Ind Med 18:653–664

    Article  Google Scholar 

  • Batista J, Schuhmacher M, Domingo JL, Corbella J (1996) Mercury in hair for a child population from Tarragona Province, Spain. Sci Total Environ 193:143–148

    Article  Google Scholar 

  • Bedello PG, Goitre M, Roncarolo G, Bundino S, Cane D (1987) Contact dermatitis to rhodium. Contact Dermatitis 17:111–112

    Article  Google Scholar 

  • Begerow J, Dunemann L (2000) Internal platinum and palladium exposure of the general population with emphasis on the exposure from automobile exhaust and dental restorative alloys. In: Zereini F, Alt F (eds) Anthropogenic platinum-group element emissions. Their impact on man and environment. Springer, Berlin

    Google Scholar 

  • Bergman A, Svedberg U, Nilsson E (1995) Contact urticaria with anaphylactic reactions caused by occupational exposure to iridium salt. Contact Dermatitis 32:14–17

    Article  Google Scholar 

  • Biagini RE, Bernstein IL, Gallagher JS, Moorman WJ, Brooks S, Gann PH (1985) The diversity of reaginic immune responses to platinum and palladium metallic salts. J Allergy Clin Immunol 76:794–802

    Article  Google Scholar 

  • Bolm-Audorff U, Bienfait HG, Burkhard J, Bury AH, Merget R, Pressel G, Schultze-Werninghaus G (1992) Prevalence of respiratory allergy in a platinum refinery. Int Arch Occup Environ Health 64:257–260

    Article  Google Scholar 

  • Boscolo P, Di Giampaolo L, Reale M, Castellani ML, Ritavolpe A, Carmignani M, Ponti J, Paganelli R, Sabbioni E, Conti P, Di Gioacchino M (2004) Different effects of platinum, palladium, and rhodium salts on lymphocyte proliferation and cytokine release. Ann Clin Lab Sci 34:299–306

    Google Scholar 

  • Boscolo P, Bellante V, Leopold K, Maier M, Di Giampaolo L, Antonucci A, Iavicoli I, Tobia L, Paoletti A, Montalti M, Petrarca C, Qiao N, Sabbioni E, Di Gioacchino M (2010) Effects of palladium nanoparticles on the cytokine release from peripheral blood mononuclear cells of non-atopic women. J Biol Regul Homeost Agents 24:207–214

    Google Scholar 

  • Brooks SM, Baker DB, Gann PH, Jarabek AM, Hertzberg V, Gallagher J, Biagini RE, Bernstein IL (1990) Cold air challenge and platinum skin reactivity in platinum refinery workers. Bronchial reactivity precedes skin prick response. Chest 97:1401–1407

    Article  Google Scholar 

  • Calverley AE, Rees D, Dowdeswell RJ (1999) Allergy to complex salts of platinum in refinery workers: prospective evaluations of IgE and Phadiatop status. Clin Exp Allergy 29:703–711

    Article  Google Scholar 

  • Cristaudo A, Picardo M, Petrucci F, Forte G, Violante N, Senofonte O, Alimonti A, Sera F (2007) Clinical and allergological biomonitoring of occupational hypersensitivity to platinum group elements. Anal Lett 40:3343–3359

    Article  Google Scholar 

  • Cristaudo A, Sera F, Severino V, De Rocco M, Di Lella E, Picardo M (2005) Occupational hypersensitivity to metal salts, including platinum, in the secondary industry. Allergy 60:159–164

    Article  Google Scholar 

  • Cromwell O, Pepys J, Parish WE, Hughes EG (1979) Specific IgE antibodies to platinum salts in sensitized workers. Clin Allergy 9:109–117

    Article  Google Scholar 

  • Daenen M, Rogiers P, Van de Walle C, Rochette F, Demedts M, Nemery B (1999) Occupational asthma caused by palladium. Eur Respir J 13:213–216

    Article  Google Scholar 

  • de la Cuadra J, Grau-Massanés M (1991) Occupational contact dermatitis from rhodium and cobalt. Contact Dermatitis 25:182–184

    Article  Google Scholar 

  • Di Gioacchino M, Di Giampaolo L, Verna N, Reale M, Di Sciascio MB, Volpe AR, Carmignani M, Ponti J, Paganelli R, Sabbioni E, Boscolo P (2004) In vitro effects of platinum compounds on lymphocyte proliferation and cytokine release. Ann Clin Lab Sci 34:195–202

    Google Scholar 

  • Di Gioacchino M, Verna N, Di Giampaolo L, Di Claudio F, Turi MC, Perrone A, Petrarca C, Mariani-Costantini R, Sabbioni E, Boscolo P (2007) Immunotoxicity and sensitizing capacity of metal compounds depend on speciation. Int J Immunopathol Pharmacol 20(2 Suppl 2):15–22

    Google Scholar 

  • Djingova R, Kovacheva P, Wagner G, Markert B (2003) Distribution of platinum group elements and other traffic related elements among different plants along some highways in Germany. Sci Total Environ 308:235–246

    Article  Google Scholar 

  • Ek KH, Rauch S, Morrison GM, Lindberg P (2004) Platinum group elements in raptor eggs, faeces, blood, liver and kidney. Sci Total Environ 334–335:149–159

    Article  Google Scholar 

  • Farago ME, Kavanagh P, Blanks R, Kelly J, Kazantzis G, Thornton I, Simpson PR, Cook JM, Delves HT, Hall GE (1998) Platinum concentrations in urban road dust and soil, and in blood and urine in the United Kingdom. Analyst 123:451–454

    Article  Google Scholar 

  • Gebel T, Lantzsch H, Plessow K, Dunkelberg H (1997) Genotoxicity of platinum and palladium compounds in human and bacterial cells. Mutat Res 389:183–190

    Article  Google Scholar 

  • Gómez B, Palacios MA, Gómez M, Sanchez JL, Morrison G, Rauch S, McLeod C, Ma R, Caroli S, Alimonti A, Petrucci E, Bocca B, Schramel P, Zischka M, Petterson C, Wass U (2002) Levels and risk assessment for humans and ecosystems of platinum-group elements in the airborne particles and road dust of some European cities. Sci Total Environ 299:1–19

    Article  Google Scholar 

  • Goossens A, Cattaert N, Nemery B, Boey L, De Graef E (2011) Occupational allergic contact dermatitis caused by rhodium solutions. Contact Dermatitis 64:158–161

    Article  Google Scholar 

  • Hooda PS, Miller A, Edwards AC (2007) The distribution of automobile catalysts-cast platinum, palladium and rhodium in soils adjacent to roads and their uptake by grass. Sci Total Environ 384:384–392

    Article  Google Scholar 

  • Hooda PS, Miller A, Edwards AC (2008) The plant availability of auto-cast platinum group elements. Environ Geochem Health 30:135–139

    Article  Google Scholar 

  • Hughes EG (1980) Medical surveillance of platinum refinery workers. J Soc Occup Med 30:27–30

    Article  Google Scholar 

  • Iavicoli I, Bocca B, Carelli G, Caroli S, Caimi S, Alimonti A, Fontana L (2007) Biomonitoring of tram drivers exposed to airborne platinum, rhodium and palladium. Int Arch Occup Environ Health 81:109–114

    Article  Google Scholar 

  • Iavicoli I, Bocca B, Caroli S, Caimi S, Alimonti A, Carelli G, Fontana L (2008a) Exposure of Rome city tram drivers to airborne platinum, rhodium, and palladium. J Occup Environ Med 50:1158–1166

    Article  Google Scholar 

  • Iavicoli I, Bocca B, Petrucci F, Senofonte O, Carelli G, Alimonti A, Caroli S (2004) Biomonitoring of traffic police officers exposed to airborne platinum. Occup Environ Med 61:636–639

    Article  Google Scholar 

  • Iavicoli I, Carelli G, Bocca B, Caimi S, Fontana L, Alimonti A (2008b) Environmental and biological monitoring of iridium in the city of Rome. Chemosphere 71:568–573

    Article  Google Scholar 

  • Iavicoli I, Carelli G, Marinaccio A, Fontana L, Calabrese E (2008c) Effects of sub-chronic exposure to palladium (as potassium hexachloro-palladate) on cytokines in male Wistar rats. Hum Exp Toxicol 27:493–497

    Article  Google Scholar 

  • Iavicoli I, Carelli G, Marinaccio A, Magrini A, Fontana L, Boscolo P, Bergamaschi A (2006) The effects of sub-acute exposure to palladium on cytokines in male Wistar rats. Int J Immunopathol Pharmacol 19(4 Suppl):21–24

    Google Scholar 

  • Iavicoli I, Fontana L, Marinaccio A, Alimonti A, Pino A, Bergamaschi A, Calabrese EJ (2011) The effects of iridium on the renal function of female Wistar rats. Ecotoxicol Environ Saf 74:1795–1799

    Article  Google Scholar 

  • Iavicoli I, Fontana L, Marinaccio A, Bergamaschi A, Calabrese EJ (2010) Iridium alters immune balance between T helper 1 and T helper 2 responses. Hum Exp Toxicol 29:213–219

    Article  Google Scholar 

  • Iavicoli I, Sgambato A, Fontana L, Marinaccio A, Leso V, Corbi M, Bergamaschi A, Calabrese EJ (2012) Effects of sub-acute exposure to rhodium (as Rh (III) chloride hydrate) on cytokines in female Wistar rats. Bull Environ Contam Toxicol 89:686–692

    Article  Google Scholar 

  • Iavicoli I, Leso V, Fontana L, Marinaccio A, Bergamaschi A, Calabrese EJ (in press) The effects of rhodium on the renal function of female Wistar rats. Chemosphere. doi:10.1016/j.chemosphere.2013.10.077

  • International Union of Pure and Applied Chemistry (IUPAC) (2004) Mechanisms of immunosensitization to metals (IUPAC Technical Report). Pure Appl Chem 76:1255–1268

    Google Scholar 

  • Jarvis KE, Parry SJ, Piper JM (2001) Temporal and spatial studies of autocatalyst-derived platinum, rhodium, and palladium and selected vehicle-derived trace elements in the environment. Environ Sci Technol 35:1031–1036

    Article  Google Scholar 

  • Johnson Matthey Publications (2013) Platinum 2013 Interim Review. http://www.platinum.matthey.com/media/1631235/platinum_2013_interim_review.pdf. Accessed on 29 November 2013

  • Kielhorn J, Melber C, Keller D, Mangelsdorf I (2002) Palladium—a review of exposure and effects to human health. Int J Hyg Environ Health 205:417–432

    Article  Google Scholar 

  • Kiilunen M, Vanhala E, Tossavainen A (2004) Occupational exposure to platinum group metals in Finland. Tox Appl Pharm 197:326–326

    Google Scholar 

  • Manno M, Viau C; in collaboration with, Cocker J, Colosio C, Lowry L, Mutti A, Nordberg M, Wang S (2010) Biomonitoring for occupational health risk assessment (BOHRA). Toxicol Lett 192: 3–16

    Google Scholar 

  • Marcheselli M, Sala L, Mauri M (2010) Bioaccumulation of PGEs and other traffic-related metals in populations of the small mammal Apodemus sylvaticus. Chemosphere 80:1247–1254

    Article  Google Scholar 

  • Mathur R, Balaram V, Satyanarayanan M, Sawant SS, Ramesh SL (2011) Anthropogenic platinum, palladium and rhodium concentrations in road dusts from Hyderabad city, India. Environ Earth Sci 62:1085–1098

    Article  Google Scholar 

  • Merget R, Caspari C, Dierkes-Globisch A, Kulzer R, Breitstadt R, Kniffka A, Degens P, Schultze-Werninghaus G (2001) Effectiveness of a medical surveillance program for the prevention of occupational asthma caused by platinum salts: a nested case-control study. J Allergy Clin Immunol 107:707–712

    Article  Google Scholar 

  • Merget R, Caspari C, Kulzer R, Breitstadt R, Rueckmann A, Schultz-Werninghaus G (1995) The sequence of symptoms, sensitization and bronchial hyperresponsiveness in early occupational asthma due to platinum salts. Int Arch Allergy Immunol 107:406–407

    Article  Google Scholar 

  • Merget R, Kulzer R, Dierkes-Globisch A, Breitstadt R, Gebler A, Kniffka A, Artelt S, Koenig HP, Alt F, Vormberg R, Baur X, Schultze-Werninghaus G (2000) Exposure-effect relationship of platinum salt allergy in a catalyst production plant: conclusions from a 5-year prospective cohort study. J Allergy Clin Immunol 105:364–370

    Article  Google Scholar 

  • Merget R, Kulzer R, Kniffka A, Alt F, Breitstadt R, Bruening T (2002) Platinum concentrations in sera of catalyst production workers are not predictive of platinum salt allergy. Int J Hyg Environ Health 205:347–351

    Article  Google Scholar 

  • Merget R, Sander I, van Kampen V, Raulf-Heimsoth M, Ulmer HM, Kulzer R, Bruening T (2010) Occupational immediate-type asthma and rhinitis due to rhodium salts. Am J Ind Med 53:42–46

    Google Scholar 

  • Merget R, Schultze-Werninghaus G, Bode F, Bergmann EM, Zachgo W, Meier-Sydow J (1991) Quantitative skin prick and bronchial provocation tests with platinum salt. Br J Ind Med 48:830–837

    Google Scholar 

  • Merget R, Schultze-Werninghaus G, Muthorst T, Friedrich W, Meier-Sydow J (1988) Asthma due to the complex salts of platinum–a cross-sectional survey of workers in a platinum refinery. Clin Allergy 18:569–580

    Article  Google Scholar 

  • Messersehmidt J, Alt F, Tolg G, Angerer J, Sehaller KH (1992) Adsorptive voltammetric procedure for the determination of platinum baseline levels in human body fluids. Fresenius J Anal Chem 343:391–394

    Article  Google Scholar 

  • Migliore L, Frenzilli G, Nesti C, Fontaner S, Sabbioni E (2002) Cytogenetic and oxidative damage induced in human lynmphocytes by platinum, rhodium and palladium compounds. Mutagenesis 17:411–417

    Article  Google Scholar 

  • Moldovan M, Palacios MA, Gómez MM, Morrison G, Rauch S, McLeod C, Ma R, Caroli S, Alimonti A, Petrucci F, Bocca B, Schramel P, Zischka M, Pettersson C, Wass U, Luna M, Saenz JC, Santamaría J (2002) Environmental risk of particulate and soluble platinum group elements released from gasoline and diesel engine catalytic converters. Sci Total Environ 296:199–208

    Article  Google Scholar 

  • Murdoch RD, Pepys J (1987) Platinum group metal sensitivity: reactivity to platinum group metal salts in platinum halide salt-sensitive workers. Ann Allergy 59:464–469

    Google Scholar 

  • Murdoch RD, Pepys J, Hughes EG (1986) IgE antibody responses to platinum group metals: a large scale refinery survey. Br J Ind Med 43:37–43

    Google Scholar 

  • Newman Taylor A (2001) Role of human leukocyte antigen phenotype and exposure in development of occupational asthma. Curr Opin Allergy Clin Immunol 1:157–161

    Article  Google Scholar 

  • Newman Taylor AJ, Cullinan P, Lympany PA, Harris JM, Dowdeswell RJ, du Bois RM (1999) Interaction of HLA phenotype and exposure intensity in sensitization to complex platinum salts. Am J Respir Crit Care Med 160:435–438

    Article  Google Scholar 

  • Niemela M, Peramaki P, Piispanen J, Poikolainen J (2004) Determination of platinum and rhodium in dust and plant samples using microwave-assisted sample digestion and ICPMS. Anal Chim Acta 521:137–142

    Article  Google Scholar 

  • Niezborala M, Garnier R (1996) Allergy to complex platinum salts: A historical prospective cohort study. Occup Environ Med 53:252–257

    Article  Google Scholar 

  • Orfao A, Ruiz-Arguelles A (1996) General concepts about cell sorting techniques. Clin Biochem 29:5–9

    Article  Google Scholar 

  • Óvári M, Muránszky G, Zeiner M, Virág I, Steffan I, Mihucz VG, Tatár E, Caroli S, Záray G (2007) Determination of Pt in urine of tram drivers by sector field inductively coupled plasma mass spectrometry. Microchem J 87:159–172

    Article  Google Scholar 

  • Palacios MA, Gómez M, Moldovan M, Gómez B (2000) Assessment of environmental contamination risk by Pt, Rh and Pd from automobile catalyst. Microchem J 67:105–113

    Article  Google Scholar 

  • Pepys J, Parish WE, Cromwell O, Hughes EG (1979) Specific IgE and IgG antibodies to platinum salts in sensitized workers. Monogr Allergy 14:142–145

    Google Scholar 

  • Petrucci F, Violante N, Senofonte O, Cristaudo A, Di Gregorio M, Forte G, Alimonti A (2005) Biomonitoring of a worker population exposed to platinum dust in a catalyst production plant. Occup Environ Med 62:27–33

    Article  Google Scholar 

  • Petrucci F, Violante N, Senofonte O, De Gregorio M, Alimenti A, Caroli S, Forte G, Cristaudo A (2004) Development of an analytical method for monitoring worker populations exposed to platinum-group elements. Microchem J 76:131–140

    Article  Google Scholar 

  • Pino A, Alimonti A, Conti ME, Bocca B (2010) Iridium, platinum and rhodium baseline concentration in lichens from Tierra del Fuego (South Patagonia, Argentina). J Environ Monit 12:1857–1863

    Article  Google Scholar 

  • Raulf-Heimsoth M, Merget R, Rihs HP, Föhring M, Liebers V, Gellert B, Schultze-Werninghaus G, Baur X (2000) T-cell receptor repertoire expression in workers with occupational asthma due to platinum salt. Eur Respir J 16:871–878

    Article  Google Scholar 

  • Ravindra K, Bencs L, Van Grieken R (2004) Platinum group elements in the environment and their health risk. Sci Total Environ 318:1–43

    Article  Google Scholar 

  • Reale M, Vianale G, Lotti LV, Mariani-Costantini R, Perconti S, Cristaudo A, Leopold K, Antonucci A, Di Giampaolo L, Iavicoli I, Di Gioacchino M, Boscolo P (2011) Effects of palladium nanoparticles on the cytokine release from peripheral blood mononuclear cells of palladium-sensitized women. J Occup Environ Med 53:1054–1060

    Article  Google Scholar 

  • Rebandel P, Rudzki E (1990) Allergy to palladium. Contact Dermatitis 23:121–122

    Article  Google Scholar 

  • Santucci B, Valenzano C, de Rocco M, Cristaudo A (2000) Platinum in the environment: frequency of reactions to platinum-group elements in patients with dermatitis and urticaria. Contact Dermatitis 43:333–338

    Article  Google Scholar 

  • Schaller KH, Angerer J, Alt F, Messersschmidt J, Wever A (1992) The determination of platinum in blood and urine as a tool for the biological monitoring of internal exposure. In: Proceedings of SPIE-international society for optical engineering 1993, international conference on monitoring of toxic chemicals and biomarkers 1716: 498–504. http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=993867. Assessed on 25 November 2013

  • Schierl R (2000) Environmental monitoring of platinum in air and urine. Microchem J 67:245–248

    Article  Google Scholar 

  • Schierl R, Fries HG, van de Weyer C, Fruhmann G (1998) Urinary excretion of platinum from platinum industry workers. Occup Environ Med 55:138–140

    Article  Google Scholar 

  • Schuhmacher M, Bellés M, Rico A, Domingo JL, Corbella J (1996) Impact of reduction of lead in gasoline on the blood and hair lead levels in the population of Tarragona Province, Spain, 1990–1995. Sci Total Environ 184:203–209

    Article  Google Scholar 

  • Schwenk M, Klein R, Templeton DM (2008) Lymphocyte subpopulations in human exposure to metals. Pure Appl Chem 80:1349–1364

    Article  Google Scholar 

  • SCOEL/SUM/150D (2011) Recommendation from the scientific committee on occupational exposure limits for platinum and platinum compounds. http://ec.europa.eu/social/BlobServlet?docId=7303&langId=en. Accessed on 28 November 2013

  • Violante N, Petrucci F, Senofonte O, Cristaudo A, Di Gregorio M, Forte G, Alimonti A (2005) Assessment of workers’ exposure to palladium in a catalyst production plant. J Environ Monit 7:463–468

    Article  Google Scholar 

  • Wang Y, Li X (2012) International symposium on safety science and technology health risk of platinum group elements from automobile catalysts. Procedia Eng 45:1004–1009

    Article  Google Scholar 

  • Wiseman CL, Zereini F (2009) Airborne particulate matter, platinum group elements and human health: a review of recent evidence. Sci Total Environ 407:2493–2500

    Article  Google Scholar 

  • Zaray G, Ovari M, Salma I, Steffan I, Zeiner M, Caroli S (2004) Determination of platinum in urine and airborne particulate matter from Budapest and Vienna. Microchem J 76:31–34

    Article  Google Scholar 

  • Zereini F, Alsenz H, Wiseman CL, Püttmann W, Reimer E, Schleyer R, Bieber E, Wallasch M (2012) Platinum group elements (Pt, Pd, Rh) in airborne particulate matter in rural vs. urban areas of Germany: concentrations and spatial patterns of distribution. Sci Total Environ 416:261–268

    Article  Google Scholar 

  • Zereini F, Alt F, Messerschmidt J, Wiseman C, Feldmann I, von Bohlen A, Müller J, Liebl K, Püttmann W (2005) Concentration and distribution of heavy metals in urban airborne particulate matter in Frankfurt am Main, Germany. Environ Sci Technol 39:2983–2989

    Article  Google Scholar 

  • Zereini F, Wiseman C, Alt F, Messerschmidt J, Müller J, Urban H (2001) Platinum and rhodium concentrations in airborne particulate matter in Germany from 1988 to 1998. Environ Sci Technol 35:1996–2000

    Article  Google Scholar 

  • Zereini F, Wiseman C, Püttmann W (2007) Changes in palladium, platinum, and rhodium concentrations, and their spatial distribution in soils along a major highway in Germany from 1994 to 2004. Environ Sci Technol 41:451–456

    Article  Google Scholar 

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  1. Institute of Public Health—Division of Occupational Medicine, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168, Rome, Italy

    Iavicoli Ivo & Leso Veruscka

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  1. Iavicoli Ivo
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  2. Leso Veruscka
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  1. Department of Environmental Analytical Chemistry, Institute for Atmospheric and Environmental Sciences, Frankfurt am Main, Germany

    Fathi Zereini

  2. School of the Environment, University of Toronto, Toronto, Canada

    Clare L.S. Wiseman

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Ivo, I., Veruscka, L. (2015). Biomonitoring of Platinum Group Elements (PGEs) in Occupational Medicine. In: Zereini, F., Wiseman, C. (eds) Platinum Metals in the Environment. Environmental Science and Engineering(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44559-4_26

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