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Gastrointestinal Complications

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Infections in Hematology

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Abstract

Gastrointestinal complications such as mucositis and graft-versus-host disease of the alimentary tract in patients treated for haematological diseases diminish the quality of life. More importantly, those patients are put at risk to serious life-threatening infectious complications, like sepsis or neutropenic enterocolitis when the patient is already immunocompromised either by neutropenia or dysfunctional cellular immunity. The treatment-induced mucosal barrier injury of the gastrointestinal tract, especially in stem cell transplant recipients, is a complex, dynamic pathobiological process that needs to be adequately detected to allow proper therapeutic interventions to be successful to warrant patient-tailored supportive management care and improve survival.

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Authors and Affiliations

  1. Department of Haematology, Radboud University Medical Centre, 9101, NL-6500 HB, Nijmegen, The Netherlands

    Nicole M. A. Blijlevens

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  1. Nicole M. A. Blijlevens
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Correspondence to Nicole M. A. Blijlevens .

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Editors and Affiliations

  1. Department of Hematology, Oncology and Palliative Care, Klinikum Ernst von Bergmann, Potsdam, Germany

    Georg Maschmeyer

  2. Department of Infectious Diseases, Infection Control and Employee Health, M.D. Anderson Cancer Center University of Texas, Houston, Texas, USA

    Kenneth V.I. Rolston

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Blijlevens, N.M.A. (2015). Gastrointestinal Complications. In: Maschmeyer, G., Rolston, K. (eds) Infections in Hematology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44000-1_12

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  • DOI: https://doi.org/10.1007/978-3-662-44000-1_12

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