Infections in Hematology

  • Georg Maschmeyer
  • Kenneth V.I. Rolston

Table of contents

  1. Front Matter
    Pages i-viii
  2. Epidemiology: Infections in Patients with Hematologic Malignancies

    1. Front Matter
      Pages 1-1
    2. Kenneth V. I. Rolston
      Pages 3-23
    3. Kenneth V. I. Rolston
      Pages 25-37
    4. Murat Akova
      Pages 63-87
  3. Diagnosis

  4. Therapeutic Strategies

    1. Front Matter
      Pages 153-153
    2. Georg Maschmeyer
      Pages 165-185
    3. Luma Dababneh, William Shomali, Issam I. Raad
      Pages 187-195
    4. Nicole M. A. Blijlevens
      Pages 197-210
    5. Martin Schmidt-Hieber
      Pages 211-226
  5. Antimicrobial Treatment (Including Important Pitfalls, Toxicities and Interactions)

    1. Front Matter
      Pages 227-227
    2. Winfried V. Kern
      Pages 229-258
    3. George R. Thompson III, Thomas F. Patterson
      Pages 259-272

About this book

Introduction

Infections are among the most frequent complications in patients with hematological malignancies and in those undergoing high-dose chemotherapy and autologous hematopoietic stem cell transplantation. A profound knowledge on the epidemiology, diagnostic approaches, treatment modalities, and prophylactic strategies is essential for the clinical management of these complications in patients who are often severely immunocompromised owing to their underlying diseases and, in particular, the intensive myelosuppressive chemo- and immunotherapy. 

This textbook provides a clinically oriented, compact, and up-to-date overview on infections in hematology patients and their management. The typical pathogens to be considered in different subgroups of patients are identified, and further aspects of the microbiological background are explored. Clinical, imaging, and laboratory-based diagnostic techniques are discussed, and therapeutic strategies appropriate to different situations are then presented, with due attention to the pitfalls, toxicities, and interactions that can arise during antimicrobial treatment. Strategies to prevent infection are also outlined, encompassing antimicrobial prophylaxis, isolation procedures, hospital hygiene, protective immunization, and the use of hematopoietic growth factors.

Keywords

Diagnosis Infection Leukemia Neutropenia Stem Cell Transplantation

Editors and affiliations

  • Georg Maschmeyer
    • 1
  • Kenneth V.I. Rolston
    • 2
  1. 1.Department of Hematology, Oncology and Palliative CareKlinikum Ernst von BergmannPotsdamGermany
  2. 2.Department of Infectious Diseases, Infection Control and Employee HealthM.D. Anderson Cancer Center University of TexasHoustonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-662-44000-1
  • Copyright Information Springer-Verlag Berlin Heidelberg 2015
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-662-43999-9
  • Online ISBN 978-3-662-44000-1
  • About this book
Industry Sectors
Biotechnology
Pharma