Abstract
Numerous factors lead to great difficulties in assessing the possible complications and diseases associated with atopic eczema (AE) [122, 248]. A major problem is correct diagnosis of AE, which has only recently been subjected to a certain standardization [29, 67a, 121, 123, 124, 125, 126, 128, 166a, 212, 273, 306a, 347]. A survey of the innumerable case reports and review articles dealing with this topic is hampered by the variable definition of AE and by imprecise description of skin lesions, particularly in the nondermatological literature, making proper classification impossible. Exact epidemiological data concerning the prevalence of atopic diseases are rare (see chapter by Schmied and Saurat, this volume). Thus, it is even more difficult to assess the frequency of diseases associated with AE, and to answer the question whether the association is incidental, rare, frequent, or constant. In addition, epidemiological studies and case reports mostly do not address the question of the causal relation between the underlying AE and the reported association. Despite these shortcomings, we will attempt to review diseases associated with AE and, if possible, discuss current ideas on causes and pathogenesis. We will omit from this review disorders dealt with in other chapters of this book (e. g. allergic contact eczema, food hypersensitivity, occupational aspects, psychosomatic abnormalities, severe immunodeficiency syndromes, side effects of glucocorticosteroids).
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Vieluf, D., Ruzicka, T. (1991). Complications and Diseases Associated with Atopic Eczema. In: Ruzicka, T., Ring, J., Przybilla, B. (eds) Handbook of Atopic Eczema. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-02671-7_7
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