Handbook of Atopic Eczema

1. Front Matter

   Pages I-XII

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2. Clinical Aspects of Atopic Eczema

   1. Front Matter

      Pages 1-1

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   2. Atopy: Condition, Disease, or Syndrome?

      • J. Ring

      Pages 3-8

   3. Epidemiology of Atopic Eczema

      • C. Schmied, J.-H. Saurat

      Pages 9-14

   4. Genetic Aspects of Atopic Eczema

      • F. Schultz Larsen

      Pages 15-26

   5. Clinical Symptoms of Atopic Eczema

      • H. Merk

      Pages 27-30

   6. Stigmata of the Atopic Constitution

      • B. Przybilla

      Pages 31-45

   7. Minimal Forms of Atopic Eczema

      • B. Wüthrich

      Pages 46-53

   8. Complications and Diseases Associated with Atopic Eczema

      • D. Vieluf, T. Ruzicka

      Pages 54-79

   9. Natural History of Atopic Eczema

      • C. F. H. Vickers

      Pages 80-83

   10. Dry Skin and Inflammation

       • M. Uehara

       Pages 84-89

   11. Occupational Aspects of Atopic Eczema with Emphasis on Atopic Hand Eczema

       • I. Rystedt

       Pages 90-97

   12. Allergic Contact Eczema and Atopic Eczema

       • Ch. Neumann, S. Marghescu

       Pages 98-106

   13. Immunodeficiency Syndromes and Atopic Eczema

       • P. Fritsch, H. Hintner

       Pages 107-116

   14. Atopic Eczema as a Psychosomatic Disease: A Model for Integrated Treatment

       • K. Bosse

       Pages 117-126

   15. Histopathological and Immunohistological Aspects of Atopic Eczema

       • E. Eckert

       Pages 127-131

   16. Clinical Aspects of Atopic Eczema: Synopsis

       • B. Przybilla, J. Ring, T. Ruzicka

       Pages 132-138

3. Pathophysiology of Atopic Eczema

   1. Front Matter

      Pages 139-139

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   2. Regulation of IgE Synthesis

      • J. C. Prinz, E. P. Rieber

      Pages 141-153

   3. IgE Receptors on Langerhans Cells: Their Significance in the Pathophysiology of Atopic Eczema

      • C. Bruijnzeel-Koomen, G. Mudde, P. Bruijnzeel, T. Bieber

      Pages 154-165

Atopic eczema is one of the most common dermatologic Altough the etiopathogenesis of the disease has not yet conditions. According to recent data, up to 10 % of all been fully elucidated, the large body of data already children may be affected. Particularly in its severe form, available provides important clues for both our atopic eczema is a distressing and even disabling disease. understanding of the disease and for daily patient care. Even the far more frequent minor forms may pose prob­ This Handbook of Atopic Eczema aims to put together lems because of their chronicity or the unpredictable current knowledge on this multifacted disease in the tendency for relapse. Atopic eczema must therefore be most comprehensive way. This volume covers the whole regarded as a major health problem, and it is one that is range of relevant information. Since each topic is dealt today drawing mounting attention, not only from the with by authors expert in that particular field, the up-to­ medical community, but increasingly from the date knowledge provided is not only extensive but also nonmedical public as well. critical. I believe that this Handbook of Atopic Eczema Since atopic eczema first emerged as a disease entity in will not only enhance our ability to treat our patients, but the early decades of this century, it has been the subject will also stimulate our efforts to fully understand this of both extensive research and intense scientific enigmatic disease. controversies.

• Dermatitis
• allergen
• allergy
• bacteria
• cytokine
• diseases
• immunity
• immunodeficiency
• immunomodulation
• inflammation
• lymphocytes
• pathogenesis
• pathophysiology
• physiology
• skin

From the reviews of the second edition:

"Atopic eczema … is one of the most common skin diseases of our time and is still increasing in prevalence dramatically all over the world. … Written by leading experts of the field, this second edition comprises the state of the art in pathophysiology, clinical medicine and therapeutic management. … All physicians will find this book most helpful in the painstaking search for the individual causal or eliciting factors." (Journal of Investigational Allergology, Vol. 16 (5), 2006)

"The Handbook of Atopic Eczema is not a small book. Its 613 generally well written pages are grouped into 66 chapters … . A researcher will quickly spot many fertile fields for investigation. Biology watchers will ponder the workings of ceramides, cytokines, and phosphodiesterase 4 inhibitors. … This book has a place on my bookshelf next to the first edition, published more than 15 years ago. In fact, it frequently has a place in my hands." (Mark V. Dahl, New England Journal of Medicine, March, 2006)

• Dermatologische Klinik und Poliklinik, Universität München, München 2, Germany

  Thomas Ruzicka, Bernhard Przybilla

• Hautklinik, Universitätskrankenhaus Eppendorf, Hamburg 20, Germany

  Johannes Ring

Policies and ethics