Clinical Symptoms of Atopic Eczema

Abstract

The clinical symptoms of atopic eczema may be precipitated at any time in a patient’s lifetime, although in most cases first signs and symptoms appear during childhood. Most patients have a personal or family history of asthma, hay fever, or eczema. At least 5% of all children are affected at some time and although a late onset is possible, it is rare. In a study performed with a group of 121 patients the average age of the patients at first manifestation of the disease was 5.5 months and the prognosis of atopic eczema turned out to be worse if the disease had begun within the first 6 months after birth, if it occurred in firstborn or only children, or if the patients had a history of allergies of the respiratory tract [19]. The data on prognosis vary greatly in the literature. In a prospective study of about 2000 children, 87% of the patients had a significant improvement of the disease after 5–20 years.

Keywords

Cholesterol Nickel Oncol Histamine Peri 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Aly RA, Maibach HI, Shinefield HR (1977) Microbial flora of atopic dermatitis. Arch Dermatol 113: 780–782PubMedCrossRefGoogle Scholar
  2. 2.
    Amlot PL, Kemeney DM, Zachary C, Parkes P, Lessof MH (1987) Oral allergy syndrome (OAS): symptoms of IgEmediated hypersensitivity to foods. Clin Allergy 17: 33–42PubMedCrossRefGoogle Scholar
  3. 3.
    Costa C, Rilliet A, Nicolet M, Saurat J-H (1989) Scoring atopic dermatitis: the simpler the better? Acta Derm Venereol 69: 41–45PubMedGoogle Scholar
  4. 4.
    Hanifin JM, Portland OR (1982) Atopic dermatitis. J Am Acad Dermatol 6: 1–13PubMedCrossRefGoogle Scholar
  5. 5.
    Hanifin JM (1984) Basic and clinical aspects of atopic dermatitis. Ann Allergy 52: 386–393PubMedGoogle Scholar
  6. 6.
    Hauser C, Wuethrich B, Matter L, Wilhelm JA, Sonnabend W, Schopfer K (1985) Staphylococcus aureus skin colonization in atopic dermatitis patients. Dermatologica 170: 35–39Google Scholar
  7. 7.
    Hauser C, Wuethrich B, Matter L, Wilhelm JA, Schopfer K (1985) Immune response to Staphylococcus aureus in atopic dermatitis. Dermatologica 170: 114–120PubMedCrossRefGoogle Scholar
  8. 8.
    Herzberg J (1972) Wenig bekannte Ausdrucksformen der Neurodermitits. Arch Derm Forsch 244: 350–352Google Scholar
  9. 9.
    Huber A, Fartasch M, Diepgen TL, Bäurle G, Hornstein OP (1987) Auftreten von Kontaktallergien beim atopischen Ekzem. Dermatoses 35: 119–123Google Scholar
  10. 10.
    Leung DYM, Geha RS (1988) Clinical and immunologic aspects of the hyperimmunoglobulin E syndrome. Hematol Oncol Clin North Am 2: 81–100Google Scholar
  11. 11.
    Linde YW (1989) Dry skin in atopic eczema. Acta Derm Venereol 69: 311–314PubMedGoogle Scholar
  12. 12.
    Linde YW, Bengtsson A, Loden M (1989) Dry skin in atopic eczema II. A surface profilometry study. Acta Derm Venereol 69: 315–319Google Scholar
  13. 13.
    Ring J (1983) Was ist Atopie? Fortschr Prakt Dermatol Venerol 10: 103–111Google Scholar
  14. 14.
    Ring J, Sedhneier F, von der Helm D, Mayr T, Walz U, Ibel H, Riepel H, Przybilla B, Reimann H.-J., Dorsch W (1986) Histamine and allergic diseases. In: Ring J, Burg G (eds) New trends in allergy. Springer, Berlin Heidelberg New York Tokyo, pp. 44–77CrossRefGoogle Scholar
  15. 15.
    Sampson HA, Broadbent KR, Broadbent JB (1989) Spontaneous release of histamine from basophils and histamine-releasing factor in patients with atopic eczema and food hypersensitivity. N Engl J Med 321: 228–232PubMedCrossRefGoogle Scholar
  16. 16.
    Wüthrich B (1975) Zur Immunpathologie der Neurodermitis constitutionalis Huber, BaselGoogle Scholar
  17. 17.
    Wüthrich B (1986) Die trockene Haut bei Neurodermitis atopica, Schweiz Rundschau Med (Praxis) 75: 193–200Google Scholar
  18. 18.
    Wüthrich B, Schudel P (1982) Die Neurodermitis atopica nach dem Kleinkindesalter. H+G 58: 1013–1023Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • H. Merk

There are no affiliations available

Personalised recommendations