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C3 Binding to Bacterial Surfaces

  • Conference paper
Bacteria, Complement and the Phagocytic Cell

Part of the book series: NATO ASI Series ((ASIH,volume 24))

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Abstract

The activation of complement and binding of C3 to the surface of pathogenic organisms are prerequisites for the biologic role of the complement system in host defense, and the virulence of many successful pathogens is the result of their ability to resist complement-mediated opsonophagocytosis and/or killing. Studies of complement binding have provided a foundation for evaluating the mechanisms of virulence of several important pathogens. More complete understanding of these organisms’ resistance to complement eventually may provide means of attenuating their virulence in the clinical setting.

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Author information

Authors and Affiliations

  1. Department of Genetics, Washington University School of Medicine, Box 8031, 4566 Scott Avenue, St. Louis, Mo, 63110, USA

    K. Lynn Cates & R. Paul Levine

Authors
  1. K. Lynn Cates
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  2. R. Paul Levine
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Editor information

Editors and Affiliations

  1. Department of Microbiology and Immunology, New York Medical College, 10595, Valhalla, NY, USA

    Felipe C. Cabello

  2. Institute of Microbiology, University of Genova, Viale Benedetto XV 10, 16132, Genova, Italy

    Carla Pruzzo

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© 1988 Springer-Verlag Berlin Heidelberg

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Cates, K.L., Levine, R.P. (1988). C3 Binding to Bacterial Surfaces. In: Cabello, F.C., Pruzzo, C. (eds) Bacteria, Complement and the Phagocytic Cell. NATO ASI Series, vol 24. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85718-8_9

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  • DOI: https://doi.org/10.1007/978-3-642-85718-8_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-85720-1

  • Online ISBN: 978-3-642-85718-8

  • eBook Packages: Springer Book Archive

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