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Adhesins, Serum Resistance and Cytolysins of E. Coli- Genetic Structure and Role in Pathogenicity

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Bacteria, Complement and the Phagocytic Cell

Part of the book series: NATO ASI Series ((ASIH,volume 24))

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Abstract

Escherichia coli strains cause infections of the gut (intestinal infections), the urinary tract (urinary tract infections, UTI), the blood (sepsis) and are also the causative agents of new born meningitis (NBM). The infections which appear outside of the intestine have been termed as extraintestinal infections (Orskov and Orskov, 1985). It has been clear for several years that certain types of the O antigen (01, 06, 018, 075, 083) and capsule (K1, K5, K12, K15) are strongly associated with such infections, as are special fimbrial adhesins, hemolysins (Hly) and iron binding chelators, such as aerobactin, a substance which takes up iron from the surrounding medium (Table 1).

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Author information

Authors and Affiliations

  1. Institut fur Genetik und Mikrobiologie, Institut fur Hygiene und Mikrobiologie, Univ. Wurzburg, Rontgenring 11, D-8700, Wurzburg, Fed. Rep. of Germany

    J. Hacker, W. Goebel & H. Hof

  2. Arbeitsgruppe f. Infektabwehrmechanismen, Ruhr Univ. Bochum, D-4630, Bochum, Fed. Rep. of Germany

    W. Konig, B. Konig & J. Scheffer

  3. Dept. of Pathology, Univ. of Cambridge, Tennis Court Road, Cambridge, UK

    C. Hughes

  4. lnstitut fur Med. Mikrobiologie, Univ. Lubeck, D2400, Lubeck, Fed. Rep. of Germany

    R. Marre

Authors
  1. J. Hacker
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  2. W. Goebel
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  3. H. Hof
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  4. W. Konig
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  5. B. Konig
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  6. J. Scheffer
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  7. C. Hughes
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  8. R. Marre
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Editor information

Editors and Affiliations

  1. Department of Microbiology and Immunology, New York Medical College, 10595, Valhalla, NY, USA

    Felipe C. Cabello

  2. Institute of Microbiology, University of Genova, Viale Benedetto XV 10, 16132, Genova, Italy

    Carla Pruzzo

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© 1988 Springer-Verlag Berlin Heidelberg

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Hacker, J. et al. (1988). Adhesins, Serum Resistance and Cytolysins of E. Coli- Genetic Structure and Role in Pathogenicity. In: Cabello, F.C., Pruzzo, C. (eds) Bacteria, Complement and the Phagocytic Cell. NATO ASI Series, vol 24. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-85718-8_17

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  • DOI: https://doi.org/10.1007/978-3-642-85718-8_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-85720-1

  • Online ISBN: 978-3-642-85718-8

  • eBook Packages: Springer Book Archive

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