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A Molecular Approach to Immunity and Pathogenicity in an Insect-Bacterial System

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Chemical Recognition in Biology

Part of the book series: Molecular Biology, Biochemistry and Biophysics ((MOLECULAR,volume 32))

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Abstract

In the Lipmann Symposium 5 years ago I called my contribution Why is insect immunity interesting? (Boman et al. 1974a). At that time we had only discovered the basic phenomena: if insects are given an injection of a nonpathogenic bacteria, they will respond by producing an antibacterial activity highly effective against a number of different bacteria both pathogenic and nonpathogenic. By the use of actinomycin D and cycloheximide we had indirectly shown that RNA and protein synthesis was required, but we had not succeeded in a biochemical characterization of any of the material synthesized as the result of an infection.

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References

  • Bloom BR (1979) Games parasites play: how parasites evade immune surveillance. Nature 279: 21–26

    Article  PubMed  CAS  Google Scholar 

  • Boman HG, Nilsson I, Rasmuson B (1972) Inducible antibacterial defence system in Drosophila. Nature 237: 232–235

    Article  PubMed  CAS  Google Scholar 

  • Boman HG, Nilsson-Faye I, Rasmuson T (1974a) In: Lipmann Symposium: Energy, biosynthesis and regulation in molecular biology, pp 103–114. de Gruyter, Berlin New York

    Google Scholar 

  • Boman HG, Nilsson-Faye I, Paul K, Rasmuson T (1974b) Insect immunity. I. Characteristics of an inducible cell-free antibacterial reaction in hemolymph of samia cynthia pupae. Infect Immun 10: 136–145

    PubMed  CAS  Google Scholar 

  • Edlund T, Sidén I, Boman HG (1976) Evidence for two immune inhibitors from Bacillus thuringiensis interfering with the humoral defense system of saturniid pupae. Infect Immun 14: 934–941

    PubMed  CAS  Google Scholar 

  • Faust RM (1975) In: Briggs JD (ed) Biological regulation of vectors, pp 31–48. A conference report. U.S. Department of Health, Education, and Welfare

    Google Scholar 

  • Faye I, Pye A, Rasmuson T, Boman HB, Boman IA (1975) Insect immunity. II. Simultaneous induction of antibacterial activity and selective synthesis of some hemolymph proteins in diapaus-ing pupae of Hyalophora cecropia and Samia cynthia. Infect Immun 12: 1426–1438

    PubMed  CAS  Google Scholar 

  • Flyg C, Kenne K, Boman HG (1980) Insect pathogenic properties of Serratia marcescens: Phage resistant mutants with a decreased resistance to Cecropia immunity and a decreased virulence to Drosophila. J Gen Microbiol, in press

    Google Scholar 

  • Gelinas RE, Kafatos FC (1977) The control of chorion protein synthesis in silkmoths: mRNA prod-duction parallels protein synthesis. Dev Biol 55: 179–190

    Article  PubMed  CAS  Google Scholar 

  • Henikoff S, Meselson M (1977) Transcription at two heat shock loci in Drosophila. Cell 12: 441–451

    Article  PubMed  CAS  Google Scholar 

  • Hultmark D, Steiner H, Rasmuson T, Boman HG (1980) Insect immunity. VI. Purification and properties of three inducible bactericidal proteins from hemolymph of immunized pupae of Hyalo-phora cecropia. Eur J Biochem 106: 7–16

    Article  PubMed  CAS  Google Scholar 

  • Powning RF, Davidson WJ (1973) Studies on insect bacteriolytic enzymes — I. Lysozyme in hemolymph of Galleria mellonella and Bombyx mori. Biochem Physiol 45B: 669–686

    Google Scholar 

  • Pye AE, Boman HG (1977) Insect immunity. III. Purification and partial characterization of immune protein P5 from hemolymph of Hyalophora cecropia pupae. Infect Immun 17: 408–414

    PubMed  CAS  Google Scholar 

  • Rasmuson T, Boman HG (1977) In: Solomon JB, Horton JD (eds) Developmental immunobiology, pp 83–90. Elsevier/North-Holland, Amsterdam

    Google Scholar 

  • Rasmuson T, Boman HG (1979) Insect immunity — V. Purification and some properties of immune protein P4 from haemolymph of Hyalophora cecropia pupae. Insect Biochem 9: 259–264

    Article  CAS  Google Scholar 

  • Schedi P, Artavanis-Tsakonas S, Steward R, Gehring WJ (1978) Two hybrid plasmids with D. melano-gaster DNA sequences complementary to mRNA coding for the major heat shock protein. Cell 14: 921–929

    Article  Google Scholar 

  • Sidén I, Dalhammar G, Telander B, Boman HG (1979) Virulence factors in Bacillus thuringiensis: Purification and properties of a protein inhibitor of immunity in insects. J Gen Microbiol 114: 45–54

    PubMed  Google Scholar 

  • Spradling A, Pardue ML, Penman S (1977) Messenger RNA in heat-shocked Drosophila cells. J Mol Biol 109: 559–587

    Article  PubMed  CAS  Google Scholar 

  • Tissières A, Mitchell HK, Tracy UN (1974) Protein synthesis in cellular salivary glands of Drosophila melanogaster: Relation to chromosomes puffs. J Mol Biol 84: 389–398

    Article  PubMed  Google Scholar 

  • Wigglesworth VB (1968) The life of insects. The new American Library, New York

    Google Scholar 

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Boman, H.G. (1980). A Molecular Approach to Immunity and Pathogenicity in an Insect-Bacterial System. In: Chapeville, F., Haenni, AL. (eds) Chemical Recognition in Biology. Molecular Biology, Biochemistry and Biophysics, vol 32. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81503-4_18

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  • DOI: https://doi.org/10.1007/978-3-642-81503-4_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-81505-8

  • Online ISBN: 978-3-642-81503-4

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