Abstract
In the Lipmann Symposium 5 years ago I called my contribution Why is insect immunity interesting? (Boman et al. 1974a). At that time we had only discovered the basic phenomena: if insects are given an injection of a nonpathogenic bacteria, they will respond by producing an antibacterial activity highly effective against a number of different bacteria both pathogenic and nonpathogenic. By the use of actinomycin D and cycloheximide we had indirectly shown that RNA and protein synthesis was required, but we had not succeeded in a biochemical characterization of any of the material synthesized as the result of an infection.
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References
Bloom BR (1979) Games parasites play: how parasites evade immune surveillance. Nature 279: 21–26
Boman HG, Nilsson I, Rasmuson B (1972) Inducible antibacterial defence system in Drosophila. Nature 237: 232–235
Boman HG, Nilsson-Faye I, Rasmuson T (1974a) In: Lipmann Symposium: Energy, biosynthesis and regulation in molecular biology, pp 103–114. de Gruyter, Berlin New York
Boman HG, Nilsson-Faye I, Paul K, Rasmuson T (1974b) Insect immunity. I. Characteristics of an inducible cell-free antibacterial reaction in hemolymph of samia cynthia pupae. Infect Immun 10: 136–145
Edlund T, Sidén I, Boman HG (1976) Evidence for two immune inhibitors from Bacillus thuringiensis interfering with the humoral defense system of saturniid pupae. Infect Immun 14: 934–941
Faust RM (1975) In: Briggs JD (ed) Biological regulation of vectors, pp 31–48. A conference report. U.S. Department of Health, Education, and Welfare
Faye I, Pye A, Rasmuson T, Boman HB, Boman IA (1975) Insect immunity. II. Simultaneous induction of antibacterial activity and selective synthesis of some hemolymph proteins in diapaus-ing pupae of Hyalophora cecropia and Samia cynthia. Infect Immun 12: 1426–1438
Flyg C, Kenne K, Boman HG (1980) Insect pathogenic properties of Serratia marcescens: Phage resistant mutants with a decreased resistance to Cecropia immunity and a decreased virulence to Drosophila. J Gen Microbiol, in press
Gelinas RE, Kafatos FC (1977) The control of chorion protein synthesis in silkmoths: mRNA prod-duction parallels protein synthesis. Dev Biol 55: 179–190
Henikoff S, Meselson M (1977) Transcription at two heat shock loci in Drosophila. Cell 12: 441–451
Hultmark D, Steiner H, Rasmuson T, Boman HG (1980) Insect immunity. VI. Purification and properties of three inducible bactericidal proteins from hemolymph of immunized pupae of Hyalo-phora cecropia. Eur J Biochem 106: 7–16
Powning RF, Davidson WJ (1973) Studies on insect bacteriolytic enzymes — I. Lysozyme in hemolymph of Galleria mellonella and Bombyx mori. Biochem Physiol 45B: 669–686
Pye AE, Boman HG (1977) Insect immunity. III. Purification and partial characterization of immune protein P5 from hemolymph of Hyalophora cecropia pupae. Infect Immun 17: 408–414
Rasmuson T, Boman HG (1977) In: Solomon JB, Horton JD (eds) Developmental immunobiology, pp 83–90. Elsevier/North-Holland, Amsterdam
Rasmuson T, Boman HG (1979) Insect immunity — V. Purification and some properties of immune protein P4 from haemolymph of Hyalophora cecropia pupae. Insect Biochem 9: 259–264
Schedi P, Artavanis-Tsakonas S, Steward R, Gehring WJ (1978) Two hybrid plasmids with D. melano-gaster DNA sequences complementary to mRNA coding for the major heat shock protein. Cell 14: 921–929
Sidén I, Dalhammar G, Telander B, Boman HG (1979) Virulence factors in Bacillus thuringiensis: Purification and properties of a protein inhibitor of immunity in insects. J Gen Microbiol 114: 45–54
Spradling A, Pardue ML, Penman S (1977) Messenger RNA in heat-shocked Drosophila cells. J Mol Biol 109: 559–587
Tissières A, Mitchell HK, Tracy UN (1974) Protein synthesis in cellular salivary glands of Drosophila melanogaster: Relation to chromosomes puffs. J Mol Biol 84: 389–398
Wigglesworth VB (1968) The life of insects. The new American Library, New York
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Boman, H.G. (1980). A Molecular Approach to Immunity and Pathogenicity in an Insect-Bacterial System. In: Chapeville, F., Haenni, AL. (eds) Chemical Recognition in Biology. Molecular Biology, Biochemistry and Biophysics, vol 32. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81503-4_18
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DOI: https://doi.org/10.1007/978-3-642-81503-4_18
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