Abstract
Although childhood non-Hodgkin’s lymphoma represents a conglomerate of histologic subtypes, it is generally agreed that most forms of the disease, if untreated, will convert to acute lymphoblastic leukemia. In recent years, this has led to the adoption of chemotherapy as a major therapeutic approach. As a result, a small but significant number of children with localized disease and the potential for cure by surgery and/or radiation therapy will be exposed unnecessarily to the deleterious effects of chemotherapy. Alternatively, radiation therapy with its delayed consequences might be recommended for eradication of localized surgically curable disease. These factors have led to the adoption of staging for the planning of rational treatment. However, the extent to which careful pretreatment evaluation should be implemented and the benefits which might accrue have not been defined. This study was undertaken in an effort to elicit such information.
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Jaffe, N. (1978). Staging in Childhood Non-Hodgkin’s Lymphoma What Are Its Benefits? How Extensive Should It Be?. In: Mathé, G., Seligmann, M., Tubiana, M. (eds) Lymphoid Neoplasias II. Recent Results in Cancer Research, vol 65. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81249-1_10
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DOI: https://doi.org/10.1007/978-3-642-81249-1_10
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