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Lymphoid Neoplasias II

Clinical and Therapeutic Aspects

  • Book
  • © 1978

Overview

Editors:
  1. Georges Mathé

    1. Institut de Cancérologie et d’Immunogénétique, Hôpital Paul-Brousse, Villejuif, France

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  2. Maxime Seligmann

    1. Laboratory of Immunochemistry and Immunopathology INSERM (U 108), and Laboratory of Cytology Research Institute on Blood Diseases, Hôpital Saint-Louis, Paris, France

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  3. Maurice Tubiana

    1. Department of Radiation, Institut Gustave-Roussy, Villejuif, France

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Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 65)

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Table of contents (27 chapters)

  1. Front Matter

    Pages I-XIV
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  2. Clinical Aspects: Staging and Therapeutic Implications

    1. Front Matter

      Pages 1-1
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    2. Introductory Remarks

      • M. Tubiana
      Pages 3-4

    3. Cellular Renewal Kinetics of Malignant Non-Hodgkin’s Lymphomas

      • K. Bremer
      Pages 5-11

    4. Clinical Staging and New Therapeutic Approaches in Multiple Myeloma

      • S. E. Salmon, B. G. M. Durie
      Pages 12-20

    5. Staging of Myeloma. A Preliminary Study of Staging Factors and Treatment in Different Stages

      • E. Ösby, B. Carlmark, P. Reizenstein
      Pages 21-27

    6. Prognostic Factors and Treatment of Multiple Myeloma: Interest of a Cyclic Sequential Chemohormonotherapy Combining Cyclophosphamide, Melphalan, and Prednisone

      • D. Belpomme, F. Simon, P. Pouillart, B. Amor, F. Feuilhade De Chauvin, A. Belpomme et al.
      Pages 28-40

    7. Pathological Staging in Adult Previously Untreated Non-Hodgkin’s Lymphomas

      • G. Bonadonna, R. Castellani, C. Narduzzi, P. Spinelli, F. Rilke
      Pages 41-50

    8. Staging in Adult Non-Hodgkin’s Lymphomas

      • S. A. Rosenberg, M. Ribas-Mundo, D. R. Goffinet, H. S. Kaplan
      Pages 51-57

    9. Invasion of the Upper Respiratory and Digestive Tract in Adult Lymphoid Neoplasias

      • J. Brugere, J. Dumont, C. Jaulerry, G. Schwaab
      Pages 58-62

    10. Non-Hodgkin’s Lymphoma of the Upper Digestive and Respiratory Tract: Histopathology and Implications for Treatment

      • J. Dumont, A. Mazabraud, A. Ennuyer, P. Bataini, J. Brugere
      Pages 63-67

    11. Staging in Childhood Non-Hodgkin’s Lymphoma What Are Its Benefits? How Extensive Should It Be?

      • N. Jaffe
      Pages 68-72

    12. Systematic Restaging in Non-Hodgkin’s Lymphoma: The Need to Define Complete Remission

      • T. S. Herman, S. E. Jones
      Pages 73-80

    13. Involvement of the Nervous System in Non-Hodgkin’s Lymphomas

      • B. Longpre, J. Lamarche, M. Rochon, M. Lepine
      Pages 81-87

    14. Leukemic (or Stage V) Lymphosarcoma

      • G. Mathé, J. L. Misset, M. Gil-Delgado, M. Delgado, F. De Vassal
      Pages 88-107

    15. Comments on “Clinical Aspects: Staging and Therapeutic Implications”

      • S. Rosenberg, M. Tubiana
      Pages 108-108

  3. Treatment of Non-Hodgkin’s Lymphomas

    1. Front Matter

      Pages 109-109
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    2. Radiotherapy of Extranodal Non-Hodgkin’s Lymphoma

      • B. Van Der Werf-Messing
      Pages 111-128

    3. Evaluation and Role of Single Chemotherapeutic Agents in Adult Non-Hodgkin’s Lymphoma

      • H. L. Davis, D. D. Von Hoff
      Pages 129-144

    4. General Strategy of Staging and Therapy of Non-Hodgkin’s Lymphomas

      • Ch. E. Myers, B. A. Chabnev
      Pages 145-148
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Keywords

About this book

We have studied 24 cases of secondarily leukemic (stage V) lymphosarcoma (LS), 31 cases of "d'emblee" leukemic LS, and ten cases of lymphoid leukemic neoplasias transitional between "d'emblee" leukemic LS and chronic lymphocytic leukemia (eLL). These cases only concern the common types ofthe WHO classification ofLS, i.e., the prolymphocytic, the lymphoblastic, and the immunoblastic. Some cases have also been classified by cell surface markers. The secondarily leukemic conversion occurred in 40% of the lymphoblastic types, in 14% of the prolymphocytic types, and in 17% of the immunoblastic types. It never occurred at stage I but could occur after any other stage. The mediastinal involvement was observed in three types, but most often in the lymphoblastic type. The prognosis after an acute lymphoid leukemia (ALL) treatment comprising active immunotherapy following chemo(radio)therapy is better for the leukemic prolymphocytic and lymphoblastic LS than for the immunoblastic type. Two patients (one of the lymphoblastic type) are in complete remission after 8 and 5 years, respectively. We have described ten cases of "d'emblee" leukemic LS with either large lymphoid or extra­ lymphoid masses, bone marrow leukemic cell involvement, and LS aspects of neoplastic cells. Mediastinal, abdominal, or other tumor masses are frequent.

Editors and Affiliations

  • Institut de Cancérologie et d’Immunogénétique, Hôpital Paul-Brousse, Villejuif, France

    Georges Mathé

  • Laboratory of Immunochemistry and Immunopathology INSERM (U 108), and Laboratory of Cytology Research Institute on Blood Diseases, Hôpital Saint-Louis, Paris, France

    Maxime Seligmann

  • Department of Radiation, Institut Gustave-Roussy, Villejuif, France

    Maurice Tubiana

Bibliographic Information

  • Book Title: Lymphoid Neoplasias II

  • Book Subtitle: Clinical and Therapeutic Aspects

  • Editors: Georges Mathé, Maxime Seligmann, Maurice Tubiana

  • Series Title: Recent Results in Cancer Research

  • DOI: https://doi.org/10.1007/978-3-642-81249-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin · Heidelberg 1978

  • Softcover ISBN: 978-3-642-81251-4Published: 16 January 2012

  • eBook ISBN: 978-3-642-81249-1Published: 06 December 2012

  • Series ISSN: 0080-0015

  • Series E-ISSN: 2197-6767

  • Edition Number: 1

  • Number of Pages: XIV, 222

  • Number of Illustrations: 11 b/w illustrations

  • Topics: Oncology, Cancer Research

  • Industry Sectors: Biotechnology, Health & Hospitals, Pharma

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