Abstract
Tumour-elicited host responses are of interest from at least two points of view: (i) they indicate an ability of the host to respond to the tumour, and (ii) they imply that the tumour is able to stimulate the host response. Both these factors may be part and partial of a specific or non-specific event. Nevertheless, with regard to the pathogenesis and therapy of malignant disease they would appear to be of paramount importance.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Eccles, Suzanne A., Alexander, P.: Macrophage content of tumours in relation to metastatic spread and host immune reaction. Nature 250, 667 (1974)
Eccles, Suzanne A., Alexander, P.: Sequestration of macrophages in growing tumours and its effect on the immunological capacity of the host. Brit. J. Cancer 30, 42 (1974)
Evans, R.: Macrophages in syngeneic animal tumours. Transplantation 14, No. 4, 468 (1972)
Gauci, C.L.: Macrophage content of human malignant melanomas. Behring Inst. Mitt. 56, 73–78 (1975)
Gauci, C.L., Alexander, P.A.: The macrophage content of some human tumours. Cancer Letters 1, 2 9 (1975)
Gauci, C.L., Wrathmell, A.B., Alexander, P.: The origin and role of blood borne monocytes in rats with a transplanted acute myelogenous leukaemia. Cancer Letters 1, 33 (1975)
Gershon, R.K., Carter, R.L., Lane, N.J.: Studies in homotrans-plantable lymphomas in hamsters. I. Histologic responses in lymphoid tissues and their relationship to metastasis. Amer. J. Pathol. 49. pp. 637–655 (1966)
Gershon, R.K., Carter, R.L., Lane, N.J.: Studies in homotrans-plantable lymphomas in hamsters. II. The specificity of the histologic responses in lymphoid tissues and their relationship to metastasis. Amer. J. Pathol. 50. pp. 137–157 (1967)
Gershon, R.K., Carter, R.L., Lane, N.J.: Studies in homotrans-plantable lymphomas in hamsters. IV. Observation on macrophages in the expression of tumour immunity. Amer. J. Pathol. 51. pp. 1111–1125 (1967)
Metcalf, D., Moore, M.A.S.: Factors modifying stem cell proliferation of myelomonocytic leukaemia cells in vitro and in vivo. J. Natl. Cancer Inst. 44, 801 (1970)
Moore, M.A.S., Williams, N., Metcalf, D.: In vitro colony formation by normal and leukaemic haemopoietic cells: Characterisation of the colony forming cells. Internat., J. Cancer 11, 143 (1973)
Underwood, J.C.E., Carr, I.: The ultrastructure of the lymphoreticular cells in non-lymphoid human neoplasms. Virchows Arch. Abt. B. Zellpath. 12, 39 (1972)
Wrathmell, A.B.: The growth pattern of two transplantable acute leukaemias of spontaneous origin in rats. Brit. J. Cancer, 33 172 (1976)
Wrathmell, A., Alexander, P.: V. Immunologic aspects of leukaemia. Growth characteristics and immunological properties of a myelo-blastic and a lymphoblastic leukaemia in pure line rats. In: Unifying Concepts of Leukaemia, Bibli. haemat., Dutcher, R.M., Chieco-Bianchi L. (eds). Basel: Karger. No. 39, pp. 649–653
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1976 Springer-Verlag Berlin · Heidelberg
About this chapter
Cite this chapter
Gauci, C.L. (1976). The Significance of the Macrophage Content of Human Tumours. In: Mathé, G., Florentin, I., Simmler, MC. (eds) Lymphocytes, Macrophages, and Cancer. Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer, vol 56. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81049-7_16
Download citation
DOI: https://doi.org/10.1007/978-3-642-81049-7_16
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-81051-0
Online ISBN: 978-3-642-81049-7
eBook Packages: Springer Book Archive