Abstract
Mineral particles are known to be responsible for many respiratory diseases and especially cause lung cancer among exposed populations. However the physico-chemical interactions of particles with biological tissues are unclear. In addition to particle morphology and size, the nature of the material and particularly its surface reactivity are involved in particles toxicity. Indeed it has been shown that some mineral particles, including asbestos, can induce the production of activated oxygen species (AOS) in relation with the presence of divalent iron at the interface solid-liquid (Zalma et al, 1987a, Mossman and Marsh, 1989).
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© 1994 Springer-Verlag Berlin Heidelberg
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Guilianelli, C., Baeza-Squiban, A., Houcine, O., Pezerat, H., Marano, F. (1994). Involvement of the Oxidative Stress in the Toxicity of Iron-Containing Particles on Tracheal Epithelium in Primary Culture. In: Davis, J.M.G., Jaurand, MC. (eds) Cellular and Molecular Effects of Mineral and Synthetic Dusts and Fibres. NATO ASI Series, vol 85. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79041-6_4
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DOI: https://doi.org/10.1007/978-3-642-79041-6_4
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