Lipid Transport from the Golgi Complex to the Plasma Membrane of Epithelial Cells
Eukaryotic cells are enveloped by a plasma membrane. The cytoplasm is filled with numerous intracellular membranes that sometimes enclose also other membraneous systems. It is well recognized that the various organelles exert different functions and possess unique protein and lipid compositions. The intracellular lipid heterogeneity is very stable and strikingly similar among the different cell types. A fundamental question is how it is generated by the dynamic interplay between local synthesis, modification, and degradation on the one hand, and the various modes of lipid traffic on the other.
KeywordsMDCK Cell Golgi Complex Sphingolipid Synthesis Cell BioI Vesicular Traffic
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