Glyco-and Cellbiology

1. Front Matter

   Pages I-VII

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2. Components and Mechanisms Involved in Protein Translocation Through the ER Membrane

   • T. A. Rapoport, D. Görlich, E. Hartmann, S. Prehn, K.-U. Kalies

   Pages 1-8

3. Protein Sorting Signals for Maintaining Transmembrane Proteins in the Endoplasmatic Reticulum

   • M. R. Jackson, P. A. Peterson

   Pages 9-21

4. Protein Retention in the Golgi Stack

   • T. Nilsson, E. Souter, R. Watson, G. Warren

   Pages 23-32

5. Signal-Mediated Targeting of Lysosomal Membrane Glycoproteins

   • K. von Figura, A. Hille-Rehfeld, L. Lehmann, C. Peters, V. Prill

   Pages 33-44

6. VIP21, Caveolae and Sorting in the Trans-Golgi Network of Epithelial Cells

   • P. Dupree, K. Fiedler, K. Simons

   Pages 45-51

7. Biogenesis of Neurosecretory Vesicles

   • W. B. Huttner, F. A. Barr, R. Bauerfeind, O. Bräunling, E. Chanat, A. Leyte et al.

   Pages 53-59

8. Lipid Transport from the Golgi Complex to the Plasma Membrane of Epithelial Cells

   • G. van Meer, M. Thielemans, I. L. van Genderen, A. L. B. van Helvoort, P. van der Bijl, K. N. J. Burger

   Pages 61-68

9. Topology and Regulation of Ganglioside Metabolism — Function and Pathobiochemistry of Sphingolipid Activator Proteins

   • K. Sandhoff, G. van Echten

   Pages 69-79

10. Why Does Baker’s Yeast Glycosylate Proteins?

    • W. Tanner

    Pages 81-89

11. Glycosylation of Nuclear and Cytoplasmic Proteins Is as Abundant and as Dynamic as Phosphorylation

    • G. W. Hart, W. G. Kelly, M. A. Blomberg, E. P. Roquemore, L.-Y. Dong, L. Kreppel et al.

    Pages 91-103

12. Novel N-Glycosylation in Eukaryotes: Laminin Contains the Linkage Unit β-Glucosylasparagine

    • R. Schreiner, Eva Schnabel, F. Wieland

    Pages 105-118

13. Reprocessing of Membrane Glycoproteins

    • R. Tauber, B. Volz, W. Kreisel, N. Loch, G. Orberger, H. Xu et al.

    Pages 119-130

14. Mutational Analysis of Carbohydrate and Phospholipid Modifications of a Cell Adhesion Protein

    • G. Gerisch, J. Faix, E. Wallraff, A. A. Noegel, A. Barth, R. Lützelschwab et al.

    Pages 131-144

15. Towards Understanding Roles of Oligosaccharides as Recognition Structures

    • T. Feizi

    Pages 145-160

16. The Biologic Significance of Glycoprotein Hormone Oligosaccharides

    • J. U. Baenziger

    Pages 161-169

17. Biosynthesis of Antibodies and Molecular Chaperones

    • A. Cremer, M. R. Knittler, I. G. Haas

    Pages 171-184

18. Function of Molecular Chaperones in Protein Folding

    • F. U. Hartl

    Pages 185-194

Understanding the biological role of the diverse oligosaccharides of glycoproteins and glycolipids has been a major challenge in cell biology. Glycosylation is an essential step during molecular recognition and is involved in protein folding, sorting, targeting and intracellular translocation. Further, glycoproteins of the cell membrane play a major role in cell adhesion, hormone function, antibody action and signal mediation. Current knowledge of the molecular and cellular mechanisms involved in these processes is presented.

• Oligosaccharid
• biochemistry
• biology
• carbohydrates
• cell
• cell biology
• cell membrane
• glycoprotein
• membrane
• metabolism
• mutation
• phosphorylation
• protein
• protein folding
• proteins

• Institut für Biochemie I der Universität, Universität Heidelberg, Heidelberg, Germany

  Felix Wieland

• Institut für Molekularbiologie und Biochemie, Freie Universität Berlin, Berlin, Germany

  Werner Reutter

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