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Topological Coupling between Promoters

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Nucleic Acids and Molecular Biology

Part of the book series: Nucleic Acids and Molecular Biology ((NUCLEIC,volume 8))

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Abstract

When transcription is initiated by RNA polymerase, a series of defined intermediate states are formed, during which the enzyme binds to the promoter and ultimately melts the helix to form an open complex (Siebenlist 1979). The first phosphodiester bond is then made, and the RNA polymerase clears the promoter in the propagation phase of transcription.

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Author information

Authors and Affiliations

  1. CRC Nucleic Acid Structure Research Group, Department of Biochemistry, The University, Dundee, DD1 4HN, UK

    D. Chen, R. P. Bowater & D. M. J. Lilley

Authors
  1. D. Chen
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  2. R. P. Bowater
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  3. D. M. J. Lilley
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Editor information

Editors and Affiliations

  1. Max-Planck-Institut für Experimentelle Medizin, Hermann-Rein-Straße 3, 37075, Göttingen, Germany

    Fritz Eckstein

  2. Biochemistry Department, University of Dundee, Dundee, DD1 4HN, UK

    David M. J. Lilley

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© 1994 Springer-Verlag Berlin Heidelberg

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Chen, D., Bowater, R.P., Lilley, D.M.J. (1994). Topological Coupling between Promoters. In: Eckstein, F., Lilley, D.M.J. (eds) Nucleic Acids and Molecular Biology. Nucleic Acids and Molecular Biology, vol 8. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78666-2_8

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  • DOI: https://doi.org/10.1007/978-3-642-78666-2_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-78668-6

  • Online ISBN: 978-3-642-78666-2

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