Abstract
The reciprocal cooperation between the genome and epigenetic factors determines the final outcome of the development of the rat spinal cord. This study presents several developmentally regulated epigenetic factors involved in the development of the neuronal and glial cell population of the rat spinal cord. By correlating their appearance and distribution patterns with known developmental events, possible roles of the factors are suggested and discussed. Neuronal markers such as neurofilaments, MAP 1A, 2 and 5, SSEA-1, and the enzyme AChE were studied during the development of the spinal cord. The glial cell markers vimentin and GFAP were also examined. In addition, the development of several major supraspinal fiber systems was studied with WGA-HRP as neuronal tracer. This summary presents only the main results for the three different spinal cord layers. Others are mentioned and, together with the former, more extensively discussed in Chaps. 5 and 6.
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© 1993 Springer-Verlag Berlin Heidelberg
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Oudega, M., Lakke, E.A.J.F., Marani, E., Thomeer, R.T.W.M. (1993). Summary. In: Development of the Rat Spinal Cord: Immuno- and Enzyme Histochemical Approaches. Advances in Anatomy Embryology and Cell Biology, vol 129. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78474-3_7
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DOI: https://doi.org/10.1007/978-3-642-78474-3_7
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-57173-5
Online ISBN: 978-3-642-78474-3
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