Abstract
Angioimmunoblastic lymphadenopathy (AIL), first described by Frizzera in 1974 [1], and B cell prolymphocytic leukemia (B-PLL), first described by Galton in 1963 [2], are two rare low-grade malignant non-Hodgkin lymphomas. An effective standard therapy does not exist for either disease. Chemotherapy is usually of no durable effect in both disorders. In B-PLL, splenectomy and leukaphersis can be useful [3, 4].
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Frizzera G, Moran EM, Rappaport H (1974) Angioimmunoblastic lymphadenopathy with dysproteinuria. Lancet I:1070–1073
Galton DAG, Wiltshaw E, Boesen E et al. (1963) Prolymphocytic leukemia. British Empire Cancer Campaign for Research 41st Annual Report, p 55
Galton DAG, Goldman JM, Wiltshaw E et al. (1974) Prolymphocytic leukemia. Br J Haematol 27:7–23
Buskard NA, Catovsky D, Okos A et al. (1976) Prolymphocytic leukemia:cell studies and treatment with leucapheresis. Hamatol Bluttransfus 18:237–253
Feremens WW, Khodadadi E (1987) Alpha-interferon-therapy in refractory angioimmunoblastic lymphadenopathy. Eur J Haematol 39:91
Jacobs P, Le Roux I, Wood L, Bolding E (1987) Interferon response in B-cell prolymphocytic leukemia. Br J Haematol 65:375–376
Delannoy A, Balligand JC, Cedant T (1987) Interferon and B-cell prolymphocytic leukemia. Br J Haematol 66:579–580
Thiel E, Schlag R, Hill W et al. (1987) B-CLL in early phase responds to recombinant alpha-2b interferon therapy as determined in a pilot study. Blut 55:205–412 A74
Ouesada JR, Reuben J, Manning JT et al. (1984) Alpha interferon for induction of remission in hairy-cell-leukemia, N Engl J Med 310:15–18
Catovsky E, O’Brien M, Melo JK et al. (1984) Hairy cell leukemia (HCL) variant:an intermediate disease between HCL and B prolymphocytic leukemia. Semin Oncol 11:362
Foon KA, Schroff RW, Gale RP (1982) Surface markers on leukemia and lymphoma cells:recent advances. Blood 60:1–19
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Springer-Verlag, Berlin Heidelberg
About this paper
Cite this paper
Trinkler, P., Mustroph, D., Hagenah, H., Mönch, H., v. Heyden, H.W. (1990). Successful Treatment of Angioimmunoblastic Lymphadenopathy (AIL) and B Cell Prolymphocytic Leukemia (B-PLL) with Interferon-α. In: Freund, M., Link, H., Welte, K. (eds) Cytokines in Hemopoiesis, Oncology, and AIDS. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75510-1_76
Download citation
DOI: https://doi.org/10.1007/978-3-642-75510-1_76
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-52281-2
Online ISBN: 978-3-642-75510-1
eBook Packages: Springer Book Archive