Successful Treatment of Angioimmunoblastic Lymphadenopathy (AIL) and B Cell Prolymphocytic Leukemia (B-PLL) with Interferon-α
Angioimmunoblastic lymphadenopathy (AIL), first described by Frizzera in 1974 , and B cell prolymphocytic leukemia (B-PLL), first described by Galton in 1963 , are two rare low-grade malignant non-Hodgkin lymphomas. An effective standard therapy does not exist for either disease. Chemotherapy is usually of no durable effect in both disorders. In B-PLL, splenectomy and leukaphersis can be useful [3, 4].
KeywordsChronic Lymphocytic Leukemia Durable Effect Hairy Cell Leukemia Cell Chronic Lymphocytic Leukemia Prolymphocytic Leukemia
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Frizzera G, Moran EM, Rappaport H (1974) Angioimmunoblastic lymphadenopathy with dysproteinuria. Lancet I:1070–1073PubMedCrossRefGoogle Scholar
Galton DAG, Wiltshaw E, Boesen E et al. (1963) Prolymphocytic leukemia. British Empire Cancer Campaign for Research 41st Annual Report, p 55Google Scholar
Galton DAG, Goldman JM, Wiltshaw E et al. (1974) Prolymphocytic leukemia. Br J Haematol 27:7–23PubMedCrossRefGoogle Scholar
Buskard NA, Catovsky D, Okos A et al. (1976) Prolymphocytic leukemia:cell studies and treatment with leucapheresis. Hamatol Bluttransfus 18:237–253PubMedGoogle Scholar
Feremens WW, Khodadadi E (1987) Alpha-interferon-therapy in refractory angioimmunoblastic lymphadenopathy. Eur J Haematol 39:91CrossRefGoogle Scholar
Jacobs P, Le Roux I, Wood L, Bolding E (1987) Interferon response in B-cell prolymphocytic leukemia. Br J Haematol 65:375–376PubMedCrossRefGoogle Scholar
Delannoy A, Balligand JC, Cedant T (1987) Interferon and B-cell prolymphocytic leukemia. Br J Haematol 66:579–580PubMedCrossRefGoogle Scholar
Thiel E, Schlag R, Hill W et al. (1987) B-CLL in early phase responds to recombinant alpha-2b interferon therapy as determined in a pilot study. Blut 55:205–412 A74CrossRefGoogle Scholar
Ouesada JR, Reuben J, Manning JT et al. (1984) Alpha interferon for induction of remission in hairy-cell-leukemia, N Engl J Med 310:15–18CrossRefGoogle Scholar
Catovsky E, O’Brien M, Melo JK et al. (1984) Hairy cell leukemia (HCL) variant:an intermediate disease between HCL and B prolymphocytic leukemia. Semin Oncol 11:362PubMedGoogle Scholar
Foon KA, Schroff RW, Gale RP (1982) Surface markers on leukemia and lymphoma cells:recent advances. Blood 60:1–19PubMedGoogle Scholar
© Springer-Verlag, Berlin Heidelberg 1990