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Microvascular Endothelial Cells from Heart

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Cell Culture Techniques in Heart and Vessel Research

Abstract

Endothelial cells from macrovascular and microvascular vessels differ in many of their physiological properties [20, 21, 36, 55, 72]. For a detailed analysis of the metabolism and the physiological function of the microvascular endothelium, cultures of microvascular cells are required. In cardiac tissue the mass of coronary endothelial cells is much smaller than the mass of cardiomyocytes (endothelium, 2%–3% of total heart mass) [3, 33, 57]. The endothelial contribution to the metabolic response of the whole heart cannot be accurately determined unless exclusive metabolic properties of the endothelial cells are investigated.

This work was supported by the Deutsche Forschungsgemeinschaft (Pi 162/6-1).

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Authors
  1. H. M. Piper
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  2. R. Spahr
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  3. S. Mertens
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  4. A. Krützfeldt
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  5. H. Watanabe
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Editors and Affiliations

  1. Physiologisches Institut, Abteilung für Herz- und Kreislaufphysiologie der Universität Düsseldorf, Moorenstr. 5, D-4000, Düsseldorf 1, Germany

    H. M. Piper

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Piper, H.M., Spahr, R., Mertens, S., Krützfeldt, A., Watanabe, H. (1990). Microvascular Endothelial Cells from Heart. In: Piper, H.M. (eds) Cell Culture Techniques in Heart and Vessel Research. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75262-9_11

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  • DOI: https://doi.org/10.1007/978-3-642-75262-9_11

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