Single-Strand Breaks and Base Damage in DNA of Human White Blood Cells in Full Blood Exposed to Ionizing Radiation Detected at Biologically Relevant Doses
Part of the
NATO ASI Series
book series (volume 54)
Both physical (UV- and X-irradiation) and chemical agents can damage cells. Of special interest are the DNA molecules, the carriers of the genetic information. Damage inflicted on DNA, unless repaired, may kill cells by interference with transcription and replication or by the induction of mutations. Non-lethal mutations may result in cells with altered properties which may contribute to ageing, heart diseases and cancer.
KeywordsStrand Break Micrococcus Luteus Base Damage Altered Property Alkaline Elution
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Van der Schans GP, Van Loon AAWM, Groenendijk RH, Baan RA (1989) Int J Radiat Biol 55: 747–760PubMedCrossRefGoogle Scholar
Van Loon AAWM, Groenendijk RH, Van der Schans GP, Lohman PHM, Baan RA (1990) (submitted to Int J Radiat Biol)Google Scholar
© Springer-Verlag Berlin Heidelberg 1991