Adult AML: The Role of Chemotherapy Intensity and Duration. Two Studies of the AML Cooperative Group

  • T. Büchner
  • W. Hiddemann
  • S. Blasius
  • P. Koch
  • G. Maschmeyer
  • C. Tirier
  • H. Sodomann
  • R. Kuse
  • E. Thiel
  • W. D. Ludwig
  • H. Seibt-Jung
  • W. Gassmann
  • H. Löffler
  • C. Aul
  • A. Heyll
  • R. Mertelsmann
  • C. H. Anders
  • M. R. Nowrousian
  • K. Straif
  • D. Hossfeld
  • K. Becker
  • A. Ho
  • H. H. Fülle
  • K.-P. Hellriegel
  • H. J. König
  • E. Lengfelder
  • W. Siegert
  • H. Bartels
  • J. Schwammborn
  • R. Donhuijsen-Ant
  • H. A. Vaupel
  • E. König
  • M. Planker
  • R. Emmerich
  • G. Middelhoff
  • K. Mainzer
  • D. Urbanitz
  • K.-H. Zurborn
  • H. Köppler
  • L. Nowicki
  • W. Augener
  • J. Karow
  • M. Schroeder
  • H. Eimermacher
  • R. Fuchs
  • L. Balleisen
  • U. Schmitz-Huebner
  • L. Leimer
  • K. H. Heitzelmann
  • B. Lathan
  • I. Meuthen
  • M. Baldus
  • R. Michels-Giermann
  • H. G. Fuhr
  • M. C. Sauerland
  • A. Heinecke
Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 33)

Abstract

Further improvement of chemotherapy for acute myeloid leukemia (AML) requires an evaluation of alternative treatment strategies as investigated in adequate prospective multicenter trials. Since no superior new drugs are available, treatment can be improved only by finding superior treatment strategies and combining them successfully, if possible. The major treatment strategies to be discussed here are
  1. a)

    long-term cylic myelosuppressive chemotherapy concepts (maintenance) and

     
  2. b)

    intensified postremission or preremission chemotherapy concepts (intensification).

     

Keywords

Toxicity Leukemia Oncol Androgen Cytosine 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • T. Büchner
  • W. Hiddemann
  • S. Blasius
  • P. Koch
  • G. Maschmeyer
  • C. Tirier
  • H. Sodomann
  • R. Kuse
  • E. Thiel
  • W. D. Ludwig
  • H. Seibt-Jung
  • W. Gassmann
  • H. Löffler
  • C. Aul
  • A. Heyll
  • R. Mertelsmann
  • C. H. Anders
  • M. R. Nowrousian
  • K. Straif
  • D. Hossfeld
  • K. Becker
  • A. Ho
  • H. H. Fülle
  • K.-P. Hellriegel
  • H. J. König
  • E. Lengfelder
  • W. Siegert
  • H. Bartels
  • J. Schwammborn
  • R. Donhuijsen-Ant
  • H. A. Vaupel
  • E. König
  • M. Planker
  • R. Emmerich
  • G. Middelhoff
  • K. Mainzer
  • D. Urbanitz
  • K.-H. Zurborn
  • H. Köppler
  • L. Nowicki
  • W. Augener
  • J. Karow
  • M. Schroeder
  • H. Eimermacher
  • R. Fuchs
  • L. Balleisen
  • U. Schmitz-Huebner
  • L. Leimer
  • K. H. Heitzelmann
  • B. Lathan
  • I. Meuthen
  • M. Baldus
  • R. Michels-Giermann
  • H. G. Fuhr
  • M. C. Sauerland
  • A. Heinecke

There are no affiliations available

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