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Targeted Plasma Drug Concentration: A New Therapeutic Approach to Relapsed Nonlymphoblastic Leukemia in Children

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Modern Trends in Human Leukemia VIII

Abstract

Chemotherapy produces approximately a 30% long-term disease-free survival in newly diagnosed children with acute nonlymphocytic leukemia (ANLL). Al-though 75%–80% of children will enter a complete remission (CR), most will relapse with resistant leukemia while receiving postremission chemotherapy.

Supported by NIH grant CA-20180 and by the American Lebanese Syrian Associated Charities (ALSAC). Dr. Mirro is a recipient of a Clinical Oncology Career Development Award from the American Cancer Society

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© 1989 Springer-Verlag Berlin Heidelberg

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Mirro, J., Crom, W.R., Kalwinsky, D.K., Santana, V.M., Baker, D.K., Belt, J. (1989). Targeted Plasma Drug Concentration: A New Therapeutic Approach to Relapsed Nonlymphoblastic Leukemia in Children. In: Neth, R., et al. Modern Trends in Human Leukemia VIII. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 32. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74621-5_13

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  • DOI: https://doi.org/10.1007/978-3-642-74621-5_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-50967-7

  • Online ISBN: 978-3-642-74621-5

  • eBook Packages: Springer Book Archive

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