Abstract
The HLA system, the major histocompatibility complex (MHC) in man, consists of a set of linked genes on chromosome 6, which code for different classes of highly polymorphic cell membrane molecules. The biological function of the HLA-A, -B, -C or class I antigens, which are expressed on almost all nucleated cells, mainly concerns immune recognition. Cytotoxic T-Iymphocytes can recognize virus-infected cells only in the context of HLA class I molecules, a phenomenon called MHC restriction (Zinkernagel and Doherty 1974). However, MHC class I antigens may also be involved in nonimmunological recognition processes (Dausset and Contu 1980).
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© 1988 Springer-Verlag Berlin Heidelberg
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Claas, F.H.J., Verduyn, W., Mommaas-Kienhuis, M., Verhoeven, W.M.A., van Ree, J.M., van Rood, J.J. (1988). Endorphin Receptors and HLA Class I Molecules. In: Ivanyi, P. (eds) MHC + X. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74026-8_31
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DOI: https://doi.org/10.1007/978-3-642-74026-8_31
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