Skip to main content
SpringerLink
Log in

Mutagens in Surface and Waste Water

  • Conference paper
Environmental Hygiene

  • 77 Accesses

Abstract

In the last years it became evident that surface and waste waters contain a lot of mutagenic contaminants which can be detected and identified with suitable methods (1, 4, 5, 6, 8, 10). In a collaborative research project with the Bundesgesundheitsamt, Institut für Wasser-, Boden- und Lufthygiene, Berlin (sampling, extraction, and chemical analysis), and the Gesellschaft für Strahlen- und Umweltforschung, Institut für Toxikologie, Munich (Ames-test) native water samples and extracts were also tested for mutagenic effects in the cell line V79. It was the aim of the study to develop a combined method for the detection and valuation of mutagenicity in water samples. Mutagenic compounds could be detected in water from various sources in a wide range of concentrations in extracts and native water samples.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Alfheim, I., A. Bjφrseth, M. Mφller, G.L. Fisher (1984) Characterization of microbial mutagens in complex samples - methodology and application. CRC Crit. Rev. Env. Control 14, Iss. 2, 91–150

    Article  Google Scholar 

  2. Ames, B.N., J. McCann, E. Yamasaki (1975). Methods for detecting carcinogens and mutagens with the Salmonella/mammalian microsome mutagenicity test. Mutation Res. 31, 347–464

    PubMed  CAS  Google Scholar 

  3. Bradley, M.O., B. Bhuvan, M.C. Francis, R. Langenbach, A. Peter son, E. Hubermann (1981) Mutagenesis by chemical agents in V79 Chinese hamster cells: A review and analysis of the literature. Mutation Res. 87, 81–142

    PubMed  CAS  Google Scholar 

  4. Douglas R., E.R. Nestmann, J.L. Betts, J.C. Mueller, E.G.-H. Lee, H.F. Stich. R.H.C. San, R.J.P Brouzes, A.L. Chmelauskas, H.D Paavila, C.C. Waiden (1980) Mutagenic activity in pulp mill effluents. In: R.L. Jolley, R.B. Cumming, W.A. Bungs (Hrsg.) Proc Third Conf on Water Ch1orination, Ann Arbor Science Publishers Inc., Ann Arbor, 865–879

    Google Scholar 

  5. Epler, J.L. (1980) The use of short-term tests in the isolation and identification of chemical mutagens in complex mixtures. In: De Serres, F.J., A. Hollaender (Eds.) Chemical Mutagens, Principles and methods for their detection, Vol. 6, Plenum Press, New York, 239–270

    Google Scholar 

  6. Grabow. W., J. Bürgern, C. Hilner (1981) Comparison of liquid-liquid extraction and resin adsorption for concentrating mutagens in Ames Salmonella/microsome assay on water. Bull. Environ. Contam. Toxicol. 27, 442 ft

    Article  PubMed  CAS  Google Scholar 

  7. Ishidate, M., S. Odashima (1977) Chromosome tests with 134 compounds on Chinese hamster cells in vitro - a screening for chemical carcinogens. Mutation Res. 48, 337–354

    Article  PubMed  CAS  Google Scholar 

  8. Jaylet, A., L. Gauthier, M. Fernandez (1987) Detection of mutagenicity in drinking water using a micronucleus test in newt larvae (Pleurodeles waltl). Mutagenesis 2, N2 3, 211–220

    Google Scholar 

  9. Ounk, G., J.J. Richard, M.D. Grieser, D. Witiak, J.L. Witiak, M.D. Arguello, R. Vick, H.J. Svec., J.S. Fritz, G.V. Calder (1974) Use of macroreticular resins in the analysis of water for trace organic contaminations, J. Chromatog. 99, 745–762

    Article  Google Scholar 

  10. Kreijl. C.F. van, H.J Kool, M. de Vries, H.J. van Kranen, E. de Greef (1980) Mutagenic activity in the rivers Rhine and Meuse in the Netherlands. Sci. Total Environ. 15, 137–147

    Article  Google Scholar 

  11. Latt, S., J. Allen. S.E. Bloom, A. Carrano, E. Falke. D. Kram, E. Schneider, R. Schreck, R. Tice, B. Whitfield, S. Wolff (1981) Sister chromatid exchanges: a report of the GENE-TOX program. Mutation Res. 87, 17–62

    PubMed  CAS  Google Scholar 

  12. Rossum, P.v., R. Webb (1978) Isolation of organic water pollutants by XAD-resins and carbon, J. Chromatog 150, 381–392

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratorium für Mutagenitätsprüfung (LMP), Technische Hochschule Darmstadt, D-6100, Darmstadt, Germany

    Harald Müllerschön & H. G. Miltenburger

Authors
  1. Harald Müllerschön
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. G. Miltenburger
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Medical Institute of Environmental, Hygiene at the University of Düsseldorf, Auf’m Hennekamp 50, 4000, Düsseldorf 1, Germany

    Norbert H. Seemayer  & Wolfgang Hadnagy  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1988 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Müllerschön, H., Miltenburger, H.G. (1988). Mutagens in Surface and Waste Water. In: Seemayer, N.H., Hadnagy, W. (eds) Environmental Hygiene. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-73766-4_9

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-73766-4_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-73768-8

  • Online ISBN: 978-3-642-73766-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation