Environmental Hygiene

1. Front Matter

   Pages I-XIV

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2. Introduction

   1. Front Matter

      Pages 1-1

      PDF

   2. General Aspects of Environmental Pollution

      • H.-W. Schlipköter

      Pages 3-4

3. In Vitro Tests

   1. Front Matter

      Pages 5-5

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   2. Cytotoxicity and Genotoxicity on Mammalian Cells

      1. Mechanisms of O3 and NO2 Toxicity in Lung Cells in Vitro

         • G. M. Alink, I. M. C. M. Rietjens

         Pages 7-10

      2. A Study on the Biological Effects of Power Station Ash

         • R. C. Brown, A. Poole, C. J. Turver

         Pages 11-14

      3. Induction of Malignant Transformation in Hamster Fetal Cells (HFC) by Diverse Environmental Carcinogens

         • J. A. DiPaolo, J. Doniger, N. C. Popescu

         Pages 15-18

      4. Biochemical and Morphological Studies on Ozone and Nitrogen Dioxide Treated Cultured Lung Cells

         • W. Ebert, E. Moll, D. Komitowski, I. Vogt-Moykopf

         Pages 19-22

      5. Induction of Sister Chromatid Exchanges by Asbestos Fibres in Combination with Other Mutagens Studied in Chinese Hamster Cells in Vitro

         • A. B. Fischer, J. L. Kaw

         Pages 23-26

      6. Evaluation of Genotoxic Effects by Environmental Pollutants Using Cell Culture Systems

         • W. Hadnagy, N. H. Seemayer

         Pages 27-31

      7. Metabolic Activation and Cytotoxicity of Airborne Particulate Matter

         • J. J. van Houdt

         Pages 32-35

      8. Mutagens in Surface and Waste Water

         • Harald Müllerschön, H. G. Miltenburger

         Pages 36-39

      9. Effects of Benzene and Other Lysosomotropic Agents on Ultraviolet Light Induced Photolysis of Lysosomes in Herpesvirus Infected Cells

         • E. V. Orsi, S. Joshi, M. Bavlsik, M. Petersheim, Y. Peng

         Pages 40-43

      10. Toxic and Genotoxic Effects of SO2 or NOx Alone and in Combination with Carcinogenic N—Nitrosamines

          • B. L. Pool, R. G. Klein, S. Monarca, P. Schmezer, W. J. Zeller

          Pages 44-48

      11. Target Organ Cells as in Vitro Test Systems for Toxicity, Mutagenicity, DNA-Repair and Transformation by Environmental Pollutants

          • M. Riebe, M. Emura, M. Aufderheide, U. Mohr

          Pages 49-53

      12. Indicators of Potential Health Risks by Airborne Particulates: Cytotoxic, Mutagenic and Carcinogenic Effects on Mammalian Cells in Vitro

          • N. H. Seemayer, W. Hadnagy, Heidrun Behrendt, R. Tomingas

          Pages 54-59

   3. Cytotoxicity and Genotoxicity on Bacterial Cells

      1. Thiaarenes — Their Environmental Occurrence and Biological Activity

         • J. Jacob, G. Grimmer

         Pages 63-67

      2. Heavy Metals and Polyaromatic Compounds in Suspended Particulates of Different Emission Sources and their Mutagenicity

         • H.-J. Moriske, H. Rüden

         Pages 68-71

      3. Microbicidal Effects of Exhaust Gases and Their Secondary Products Under Field Conditions

         • S. Waldner-Sander, K. Botzenhart

         Pages 72-75

   4. Specific Effects on Cell Functions

      1. Tumor Promoter PMA and Crosslinking of surface Immunoglobulins induce Superoxide production in Epstein-Barr-Virus-infected Human B Lymphocytes: a novel pathway for the production of potentially mutagenic species

         • F.-E. Maly, A. R. Cross, O. T. G. Jones, A. L. de Weck

         Pages 79-82

Environmental pollution raises serious concern worldwide about effects on human health. Based on a recent meeting, this book focuses on diverse aspects of environmental hygiene, dealing with the evaluation of chemical and physical agents and their relevance to human health. To assess the toxicity, mutagenicity and carcinogenicity of environmental pollutants, a variety of methodological approaches, both in vivo and in vitro, as tissue cultures, isolated organs and animal models, were developed and are described in detail. Data on human exposure, biological monitoring and epidemiological studies are also included. Problems of environmental control and legislation as well as possible provisional steps are discussed.

• Activation
• Alveolar macrophages
• Macrophages
• Toxicology
• environment
• influence
• leukocytes
• polymorphonuclear leukocytes
• ecotoxicology

• Medical Institute of Environmental, Hygiene at the University of Düsseldorf, Düsseldorf 1, Germany

  Norbert H. Seemayer, Wolfgang Hadnagy

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