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The Unique Chemical Composition of Nephrocalcinosis in Experimental Renal Insufficiency, Disturbances of Cellular Calcium Metabolism, and Protective Effect of Verapamil Against Nephrocalcinosis

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Nephrocalcinosis Calcium Antagonists and Kidney

Abstract

Clinical consequences of the deranged calcium metabolism are multiple. Mostly they manifest themselves dramatically as do renal stones or calcification of the soft tissues. These entities were known to ancient physicians and the Hippocrates recommendation to avoid large quantities of milk for an infant’s nursing (some should be substituted with a diluted wine) represents an indication of a deep intuitive awareness of what Sir Hamphry Davy will refer to in 1808 as calcium, and of its role in the “milk-alkali syndrome.”

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© 1988 Springer-Verlag Berlin Heidelberg

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Goligorsky, M.S. et al. (1988). The Unique Chemical Composition of Nephrocalcinosis in Experimental Renal Insufficiency, Disturbances of Cellular Calcium Metabolism, and Protective Effect of Verapamil Against Nephrocalcinosis. In: Bichler, KH., Strohmaier, W.L. (eds) Nephrocalcinosis Calcium Antagonists and Kidney. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-72857-0_10

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  • DOI: https://doi.org/10.1007/978-3-642-72857-0_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-72859-4

  • Online ISBN: 978-3-642-72857-0

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