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Segregation of Maternal Na+/K+-pump α1 and β3 mRNAs to Animal Blastomeres of Early Xenopus Embryos

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The Sodium Pump

Abstract

During oogenesis Xenopus oocytes accumulate a large stockpile of Na+/K+-pump molecules (10) consisting of al and ß3 subunits (7). Fully-grown oocytes continue to synthesize significant amounts of al subunits, but the formation of new α1/ß3 complexes is strictly limited by a very low level of synthesis of endogenous ß3 subunits (1). The al subunits that fail to find a ß3 subunit are maintained in an assembly-competent form (1) and can be rescued to leave the endoplasmic reticulum (ER) by pairing with exogenous ß1 subunits synthesized later from injected cRNAs (9).

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References

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Authors and Affiliations

  1. Department of Cell Physiology, Max-Planck-Institute of Biophysics, Heinrich-Hoffmann-Str. 7, D-60528, Frankfurt/Main, Germany

    S. Friehs & G. Schmalzing

Authors
  1. S. Friehs
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  2. G. Schmalzing
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Editors and Affiliations

  1. Max-Planck-Institut für Biophysik, Kennedyallee 70, 60596, Frankfurt, Germany

    Ernst Bamberg

  2. Institut für Biochemie, Universität Gießen, Frankfurter Str. 100, 35392, Gießen, Germany

    Wilhelm Schoner

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© 1994 Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt

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Friehs, S., Schmalzing, G. (1994). Segregation of Maternal Na+/K+-pump α1 and β3 mRNAs to Animal Blastomeres of Early Xenopus Embryos. In: Bamberg, E., Schoner, W. (eds) The Sodium Pump. Steinkopff. https://doi.org/10.1007/978-3-642-72511-1_36

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  • DOI: https://doi.org/10.1007/978-3-642-72511-1_36

  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-642-72513-5

  • Online ISBN: 978-3-642-72511-1

  • eBook Packages: Springer Book Archive

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