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Endo- Exocytotic Sorting of Na+/K+-Pumps in Developing Oocytes and Embryos of Xenopus laevis

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The Sodium Pump

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Abstract

Amphibian oocytes are physiologically arrested at the G2/M border of the first meiotic prophase until progesterone triggers the resumption of the meiotic cell cycle. Within a few hours, immature oocytes are transformed by a process designated meiotic maturation into mature oocytes ready to be shed and fertilized (see Ref. 9 for review). In parallel to the well known nuclear changes, a profound reorganization of the plasma membrane takes place that is reflected by a marked reduction of the surface area (8), a near complete membrane depolarization, and a downregulation of virtually all transmembrane transport systems (see Ref. 15 for review). As a consequence of these changes, the plasma membrane of mature oocytes has an extremely low ionic permeability, in contrast to the plasma membrane of immature oocytes, which exhibits high permeability for ions.

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Author information

Authors and Affiliations

  1. Department of Cell Physiology, Max-Planck-Institute of Biophysics, Heinrich-Hoffmann-Str. 7, D-60528, Frankrfurt/Main, Germany

    G. Schmalzing

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  1. G. Schmalzing
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Editors and Affiliations

  1. Max-Planck-Institut für Biophysik, Kennedyallee 70, 60596, Frankfurt, Germany

    Ernst Bamberg

  2. Institut für Biochemie, Universität Gießen, Frankfurter Str. 100, 35392, Gießen, Germany

    Wilhelm Schoner

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© 1994 Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt

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Schmalzing, G. (1994). Endo- Exocytotic Sorting of Na+/K+-Pumps in Developing Oocytes and Embryos of Xenopus laevis . In: Bamberg, E., Schoner, W. (eds) The Sodium Pump. Steinkopff. https://doi.org/10.1007/978-3-642-72511-1_27

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  • DOI: https://doi.org/10.1007/978-3-642-72511-1_27

  • Publisher Name: Steinkopff

  • Print ISBN: 978-3-642-72513-5

  • Online ISBN: 978-3-642-72511-1

  • eBook Packages: Springer Book Archive

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