Skip to main content
SpringerLink
Log in

Effect of Etofibrate on Platelet Function in Hyperlipidemic Patients

  • Conference paper
Drugs Affecting Lipid Metabolism

Part of the book series: Proceedings in Life Sciences ((LIFE SCIENCES))

  • 211 Accesses

Abstract

Current theory holds that atherosclerotic plaque formation results from injuries which damage the histological and functional integrity of the endothelium (for review see e.g. Miller 1984). As causative factors low density lipoproteins (LDL), hemodynamic shearing at bifurcations of the arterial system, nicotine, and others have been identified in endothelial damage. Once the endothelial lining is disrupted, plasma components, especially LDL, are deposited in the denuded area followed by migration of smooth muscle cells into the subendothelial space.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Krüger B, Lang E (1984) Effects of two different doses of etofibrate on platelet aggregation and lipoproteins. Eur J Clin Invest 14(2), pt II, Abstr 46

    Google Scholar 

  • Miller NE (1984) Atherosclerosis: mechanisms and approaches to therapy. Raven, New York

    Google Scholar 

  • Puglisi L, Maggi F, Accomazzo MR, Schatton W (1984) The antiatherosclerotic property of etofibrate. Eur J Clin Invest 14(2), pt II, Abstr 44

    Google Scholar 

  • Wagner HA, Cremer P, Creutzfeldt C, Seidel D (1984) Influence of etofibrate on prostaglandins and lipoproteins in 11 hyperlipoproteinemics. Eur J Clin Invest 14(2), pt II, Abstract 45

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Ospedale Beata Vergine, CH-6850, Mendrisio, Switzerland

    G. Noseda, C. Fragiacomo & A. Radelli

  2. Institute of Pharmacological Sciences, University of Milan, Milan, Italy

    E. Bosisio, E. De Fabiani & G. Galli

Authors
  1. G. Noseda
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. C. Fragiacomo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. Radelli
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. E. Bosisio
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. E. De Fabiani
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. G. Galli
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. School of Pharmacy, University of Milan, Via Balzaretti 9, 20133, Milan, Italy

    Rodolfo Paoletti (Dean) (Dean)

  2. The Wistar Institute, 3601 Spruce Street, Philadelphia, PA, 19104, USA

    David Kritchevsky (Associate Director) (Associate Director)

  3. 238 Chatham Way, West Chester, PA, 19380, USA

    William L. Holmes

Rights and permissions

Reprints and permissions

Copyright information

© 1987 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Noseda, G., Fragiacomo, C., Radelli, A., Bosisio, E., De Fabiani, E., Galli, G. (1987). Effect of Etofibrate on Platelet Function in Hyperlipidemic Patients. In: Paoletti, R., Kritchevsky, D., Holmes, W.L. (eds) Drugs Affecting Lipid Metabolism. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71702-4_74

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-71702-4_74

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-71704-8

  • Online ISBN: 978-3-642-71702-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation