Abstract
The 7α-hydroxylation of cholesterol is the initial and major rate-limiting step in the conversion of cholesterol into bile acids. The enzyme system cholesterol 7α-hy-droxylase, which catalyzes the introduction of the hydroxyl group in the 7α-position of the cholesterol molecule, is a mixed-function oxidase, cytochrome P 450-dependent and is located in the smooth endoplasmic reticulum of the liver cell (Myant and Mitropoulos 1977).
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© 1987 Springer-Verlag Berlin Heidelberg
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Bosisio, E. (1987). Dietary and Pharmacological Control of Cholesterol 7α-Hydroxylase. In: Paoletti, R., Kritchevsky, D., Holmes, W.L. (eds) Drugs Affecting Lipid Metabolism. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71702-4_4
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DOI: https://doi.org/10.1007/978-3-642-71702-4_4
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