Cytoskeletal Organization in Acute Leukemias

  • A. Schmitt-Gräff
  • M. E. Scheulen
  • G. Gabbiani
Conference paper
Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 30)


The cytoplasm of eukaryotic cells contains three fibrous systems: microfilaments, intermediate filaments and microtubules. Microfilaments are polymers of actin, microtubules are made up of tubulin subunits and intermediate filaments are composed of at least five different classes of proteins according to tissue origin. It is now widely recognized that cytoskeletal and their associated proteins play an important role in cell motility, cell shape, endo- and exocytotic processes, organelle movement, and control of surface receptor functions[1].


Acute Myeloid Leukemia Intermediate Filament Filament Network Organelle Movement Myeloid Blast 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • A. Schmitt-Gräff
    • 1
  • M. E. Scheulen
    • 2
  • G. Gabbiani
  1. 1.Department of PathologyUniversity of DüsseldorfDüsseldorfFederal Republic of Germany
  2. 2.Department of Internal Medicine, West German Tumor CenterUniversity of Essen Medical SchoolEssenGermany

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