Cytoskeletal Organization in Acute Leukemias
The cytoplasm of eukaryotic cells contains three fibrous systems: microfilaments, intermediate filaments and microtubules. Microfilaments are polymers of actin, microtubules are made up of tubulin subunits and intermediate filaments are composed of at least five different classes of proteins according to tissue origin. It is now widely recognized that cytoskeletal and their associated proteins play an important role in cell motility, cell shape, endo- and exocytotic processes, organelle movement, and control of surface receptor functions.
KeywordsAcute Myeloid Leukemia Intermediate Filament Filament Network Organelle Movement Myeloid Blast
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