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Cytoskeletal Organization in Acute Leukemias

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Acute Leukemias

Abstract

The cytoplasm of eukaryotic cells contains three fibrous systems: microfilaments, intermediate filaments and microtubules. Microfilaments are polymers of actin, microtubules are made up of tubulin subunits and intermediate filaments are composed of at least five different classes of proteins according to tissue origin. It is now widely recognized that cytoskeletal and their associated proteins play an important role in cell motility, cell shape, endo- and exocytotic processes, organelle movement, and control of surface receptor functions[1].

Supported in part by the Swiss National Science Foundation, Grant no. 3.178-0.82, by the Ernst and Lucie Schmidheiny Foundation and by the Deutsche Forschungsgemeischaft, Bonn-Bad Godesberg.

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© 1987 Springer-Verlag Berlin Heidelberg

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Schmitt-Gräff, A., Scheulen, M.E., Gabbiani, G. (1987). Cytoskeletal Organization in Acute Leukemias. In: Büchner, T., Schellong, G., Hiddemann, W., Urbanitz, D., Ritter, J. (eds) Acute Leukemias. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71213-5_46

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  • DOI: https://doi.org/10.1007/978-3-642-71213-5_46

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-16556-9

  • Online ISBN: 978-3-642-71213-5

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