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Table of contents

  1. Front Matter
    Pages I-XXVI
  2. Biology, Cytogenetics and Morphology in Acute Leukemias

    1. Front Matter
      Pages 1-1
    2. P. Dörmer, G. Ucci, Ch. Hershko, W. Wilmanns
      Pages 3-9
    3. H. Löffler, W. Kayser, N. Schmitz, E. Thiel, D. Hoelzer, T. Büchner et al.
      Pages 21-27
  3. Acute Myeloid Leukemia in Adults

    1. Front Matter
      Pages 29-29
    2. K. R. Rai, J. Cuttner, J. F. Holland, R. Davis, R. Mayer, O. R. McIntyre et al.
      Pages 31-34
    3. C. Sauter, P. Alberto, W. Berchtold, M. Fopp, J. Gmür, A. Gratwohl et al.
      Pages 38-44
    4. M. Marty, E. Lepage, H. Guy, D. Bordessoule, B. Desablens, J. L. Harousseau et al.
      Pages 50-56
    5. T. Büchner, W. Hiddemann, D. Urbanitz, H. Kreutzmann, G. Maschmeyer, F. Wendt et al.
      Pages 57-63
    6. D. Urbanitz, Th. Büchner, H. Pielken, P. Koch, W. D. Ludwig, G. Maschmeier et al.
      Pages 64-68
  4. Acute Myeloid Leukemia in Children

    1. Front Matter
      Pages 69-69
    2. U. Creutzig, J. Ritter, H. Riehm, M. Budde, G. Schellong
      Pages 71-75
    3. H. Weinstein, H. Grier, R. Gelber, B. Camitta, M. Link, M. Delorey et al.
      Pages 88-92
  5. Acute Lymphoblastic Leukemia in Adults

    1. Front Matter
      Pages 93-93
    2. D. Hoelzer, E. Thiel, H. Löffler, A. Ganser, H. Heimpel, T. Büchner et al.
      Pages 104-110
    3. M. Andreeff, J. Gaynor, D. Chapman, C. Little, T. Gee, B. D. Clarkson
      Pages 111-124
    4. D. Fière, E. Archimbaud, J. M. Extra, M. Marty, B. David, F. Witz et al.
      Pages 125-129
  6. Acute Lymphoblastic Leukemia in Children

    1. Front Matter
      Pages 137-137
    2. H. Riehm, H.-J. Feickert, M. Schrappe, G. Henze, G. Schellong
      Pages 139-146
    3. G. K. Rivera, E. Kovnar, C.-H. Pui, G. V. Dahl, M. Abromowitch, J. J. Ochs et al.
      Pages 156-160
    4. P. S. Gaynon, P. G. Steinherz, G. H. Reaman, W. A. Bleyer, H. Sather, G. D. Hammond
      Pages 167-172
  7. Supportive Care in Acute Leukemia

    1. Front Matter
      Pages 173-173
    2. J. Ritter, D. Voigt, G. Hoese, G. Schellong
      Pages 182-187
  8. Bone Marrow Transplantation in Acute Leukemias

    1. Front Matter
      Pages 195-195
    2. H. J. Kolb, C. Bender-Götze, R. J. Haas, S. Thierfelder, W. Wilmanns
      Pages 204-212
    3. U. W. Schaefer, D. W. Beelen, H. K. Mahmoud, K. Quabeck, R. Becher, C. G. Schmidt et al.
      Pages 213-216
    4. D. Niethammer, G. Ehninger, R. Dopfer, P. Ostendorf, H. D. Waller, C. Bender-Götze et al.
      Pages 217-225
    5. B. Löwenberg, J. Abels, D. W. van Bekkum, W. Sizoo, W. D. H. Hendriks, M. B. van’t Veer et al.
      Pages 233-236
  9. Poster Session

    1. Front Matter
      Pages 237-237
    2. Basic Research

      1. A. Raghavachar, C. R. Bartram, E. Kleihauer, B. Kubanek
        Pages 251-255
      2. G. Heil, A. Ganser, D. Hoelzer, E. Kurrle, W. Heit, H. Heimpel
        Pages 261-264
      3. W. D. Ludwig, W. Hiddemann, F. Herrmann, H. Seibt, B. Komischke, H. Rühl
        Pages 265-270
      4. P. A. Maubach, B. Emmerich, A. Ogilvie, P. Haas, W. Hiddemann, J. Rastetter
        Pages 271-277

About these proceedings

Introduction

The progress in the treatment of childhood and adult acute leukemias within the last 10-15 years was pioneered by the work of single institl:tions incorporating modern leukemia cell research and pharmacology into the design of chemotherapeutic regimens. These new approaches, however, had to be validated by representative prospective studies in order to clearly demonstrate the efficacy of special concepts and to identify prognostic determinants and differences between patient subgroups. It was therefore the aim of the First International Symposium "Acute Leukemias: Prognostic Factors and Treatment Strategies" held in Munster in 1986 to provide a broad overview over the present status of chemotherapy and bone marrow transplantation in childhood and adult leukemias with special emphasis on the results of multicenter trials recruiting large numbers of patients in Europe and oversea countries. In addition, new aspects of cytogenetics, leukemia cell biology and modern diagnostic techniques as well as improvements in supportive treatment were covered. In an attempt to summarize the major results presented during this meeting, which are given in detail in the present book, the following conclusions may be drawn: In adults with acute myeloid leukemia complete remissions are achieved in 60 to 70% of all patients and translate into long­ term remissions in 15 to 25% of responders. Monthly maintenance chemotherapy was found to prolong remission duration significantly. In addition, late intensification, early consolidation or, as a new approach.

Keywords

bone marrow cell cell biology chemotherapy childhood cytogenetics genetics leukemia pharmacology transplantation

Editors and affiliations

  • T. Büchner
    • 1
  • G. Schellong
    • 1
  • W. Hiddemann
    • 1
  • D. Urbanitz
    • 1
  • J. Ritter
    • 1
  1. 1.Departments of Internal Medicine and PediatricsUniversity of MünsterMünsterFederal Republic of Germany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-71213-5
  • Copyright Information Springer-Verlag Berlin Heidelberg 1987
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-16556-9
  • Online ISBN 978-3-642-71213-5
  • Series Print ISSN 0440-0607
  • Buy this book on publisher's site
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