Skip to main content

The Childhood AML Studies BFM-78 and -83: Treatment Results and Risk Factor Analysis

  • Conference paper
Acute Leukemias

Part of the book series: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 30))

Abstract

Within the last 10 years the prognosis of childhood AML has been improved by more intensive combination chemotherapy and better supportive care, but not in the same degree as in childhood ALL [1]. The German AML studies, BFM-78 and -83, demonstrate increasing rates of long-lasting remissions. The large number of patients have allowed us to define prognostic factors in childhood AML.

Supported by the Bundesminister für Forschung und Technologie, FRG.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Henze, G, Langermann HJ, Fengler R, Brandeis M, Evers KG, Gadner H, Hinderfeld L, Jobke A, Kornhuber B, Lampert F, Lasson U, Ludwig R, Müller-Weihrich St, Neidhardt M, Nessler G, Niethammer D, Rister M, Ritter J, Schaaff A, Schellong G, Stollmann B, Treuner J, Wahlen W, Weinel P, Wehinger H, Riehm H (1982) Therapiestudie BFM 79/81 zur Behandlung der akuten lymphoblastischen Leukämie bei Kindern und Jugendlichen: intensivierte Reinduktionstherapie für Patientengruppen mit unterschiedlichem Rezidivrisiko. Klin Pädiat 194: 195–203

    Article  CAS  Google Scholar 

  2. Creutzig U, Ritter J, Riehm H, Langermann HJ, Henze G, Kabisch H, Niethammer D, Jürgens H, Stollmann B, Lasson U, Kaufmann U, Löffler H, Schellong G (1985) Improved treatment results in childhood acute myelogenous leukemia: a report of the German cooperative study AML-BFM-78. Blood 65: 298–304

    PubMed  CAS  Google Scholar 

  3. Preisler HD, Rustum Y, Henderson ES, Bjornsson S, Creaven PJ, Higby DJ, Freeman A, Gailani S, Naeher C (1979) Treatment of acute nonlymphocytic leukaemia: use of anthracycline cytosine arabinoside induction therapy and comparison of two maintenance regimens. Blood 53: 455–464

    PubMed  CAS  Google Scholar 

  4. Kaplan EL, Meier P (1958) Non-parametric estimation from incomplete observations. J Am Stat Assoc 53: 457–481

    Article  Google Scholar 

  5. Breslow NE, Day NE (1980) Statistical methods in cancer research. IARC Scientific Publication 32, Lyon, vol 1

    Google Scholar 

  6. Miller RG (1981) Survival analysis. Wiley, New York

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1987 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Creutzig, U., Ritter, J., Riehm, H., Budde, M., Schellong, G. (1987). The Childhood AML Studies BFM-78 and -83: Treatment Results and Risk Factor Analysis. In: Büchner, T., Schellong, G., Hiddemann, W., Urbanitz, D., Ritter, J. (eds) Acute Leukemias. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71213-5_12

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-71213-5_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-16556-9

  • Online ISBN: 978-3-642-71213-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics