Abstract
The objective of this chapter is to provide a broad, bird’s-eye view of the problems of intestinal permeation and permeability. The aim of the subsequent chapters is to discuss these problems in more detail. Two parts of the intestinal tract can be clearly distinguished both morphologically and functionally in the human, in other mammals, in birds, and in some amphibians: the small intestine and the large intestine. The small intestine begins at the pylorus as duodenum, continues as jejunum into the aboral part called ileum. The large intestine, or colon, originates at the ileocecal junction and, in humans, has three parts: the ascending, transverse, and descending colon; the latter continues into the rectum. The cecum is a blind sac at the beginning of the colon; in humans this part of the gut apparently is of minor functional significance.
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Csáky, T.Z. (1984). Intestinal Permeation and Permeability: an Overview. In: Csáky, T.Z. (eds) Pharmacology of Intestinal Permeation I. Handbook of Experimental Pharmacology, vol 70 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69505-6_2
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DOI: https://doi.org/10.1007/978-3-642-69505-6_2
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