Skip to main content
SpringerLink
Log in

Gastrointestinal Drugs

  • Chapter
Allergic Reactions to Drugs

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 63))

Abstract

This review is based on information in the literature and on allergic reactions reported to the Swedish National Board of Health and Welfare from 1965 to 1979. All doctors in Sweden are supposed to report all severe side effects and side effects which are not well known, especially adverse reactions to new drugs. The effects are then judged as certain, probable, or possible. Only certain and probable allergic reactions will be considered here.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Abramowitz EW (1918) Erythema multiforme associated with cutaneous pigmentation (melanin): clinical and pathologic report of five cases. J Cutan Dis 36:11–12

    Google Scholar 

  • Abramowitz EW (1935) Reactions due to Phenolphthalein. A study of their pathogenesis. Arch Dermatol Syphilol 31:777–795

    CAS  Google Scholar 

  • Abramowitz EW, Russo JJ (1940) Fixed eruption from magnesium hydroxide. Polysensitivity. Arch Dermatol Syphilol 41:707–710

    Google Scholar 

  • Ahmed AH, McLarty DG, Sharma SK, Masawe AEJ (1978) Stevens-Johnson syndrome treatment with Cimetidine. Lancet 2:433

    Article  PubMed  CAS  Google Scholar 

  • Alexander HL (1955) Reactions with drug therapy. Saunders, Philadelphia

    Google Scholar 

  • Al-Kawas FH, Lenes BA, Sacher RA (1979) Cimetidine and agranulocytosis. Ann Intern Med 90:992–993

    PubMed  CAS  Google Scholar 

  • Arndt KA, Jick H (1976) Rates of cutaneous reactions to drugs. A report from the Boston collaborative drug surveillance program. JAMA 235:918–923

    Article  PubMed  CAS  Google Scholar 

  • Arnold F, Doyle PJ, Bell G (1978) Acute pancreatitis in a patient treated with Cimetidine. Lancetl:382–383

    Google Scholar 

  • Balme HW, Huskisson EC (1977) Side effects of penicillamine other than nephropathy and their management. In: Penicillamine research in rheumatoid disease. Fabritius, Oslo, pp 250–254

    Google Scholar 

  • Barzilai D, Dickstein G, Enat R, Bassan H, Lichtig C, Gellei B (1978) Cholestatic jaundice caused by D-penicillamine. Ann Rheum Dis 37:98–100

    Article  PubMed  CAS  Google Scholar 

  • Bennett RH, Schwartz E (1934) Castor bean dust sensitization. J Allergy 5:427–431

    Article  Google Scholar 

  • Bergström G, Holst R (1972) Perianala hudförändringar orsakade av antrakinon i avföringsmedel. Lakartidningen 69:28–29

    PubMed  Google Scholar 

  • Bernstein F (1931) Ãœberempfindlichkeit gegen Phenolphthalein. Dermatol Z 62:368–369

    Article  Google Scholar 

  • Bernton HS (1970) The allergenicity of psyllium seed. Med Ann DC 39:313–317

    PubMed  Google Scholar 

  • Blank P (1945) Sensitization of the oral administration of castor oil. Ann Allergy 3:297

    Google Scholar 

  • Block MB, Genant HK, Kirsner JB (1970) Pancreatitis as an adverse reaction to salicylazosulfapyridine. N Engl J Med 282:380–382

    Article  PubMed  CAS  Google Scholar 

  • Bowen R (1939) Karaya gum as a cause of urticaria. Arch Dermatol Syphilol 39:506–509

    Google Scholar 

  • Brown EB, Crepea SB (1947) Allergy (asthma) to ingested gum tragacanth. J Allergy 18:214–216

    Article  PubMed  CAS  Google Scholar 

  • Browne SG (1964) Fixed eruption in deeply pigmented subjects: clinical observations on 350 patients. Br Med J 2:1041–1044

    Article  PubMed  CAS  Google Scholar 

  • Bruinsma W (1977) A guide to drug eruptions. The file of adverse reactions to the skin. University of Amsterdam

    Google Scholar 

  • Bullen SS (1934) Perennial hay fever from Indian gum (karaya gum). J Allergy 5:484–487

    Article  Google Scholar 

  • Busse W, Schoenwetter WF (1975) Asthma from psyllium in laxative manufacture. Ann Intern Med 83:361–362

    PubMed  CAS  Google Scholar 

  • Carroll OM, Bryan PA, Robinson RJ (1966) Stevens-Johnson syndrome associated with long-acting sulfonamides. JAMA 195:691–693

    Article  PubMed  CAS  Google Scholar 

  • Chester AC, Diamond LH, Schreiner GE (1978) Hypersensitivity to salicylazosulfapyridine. Renal and hepatic toxic reactions. Arch Intern Med 138:1138–1139

    Article  PubMed  CAS  Google Scholar 

  • Collins JR (1968) Adverse reactions to salicylazosulfapyridine (azulfide) in the treatment of ulcerative colitis. South Med J 61:354–358

    Article  PubMed  CAS  Google Scholar 

  • Constantinides KA (1976) Eosinophilic pneumonia. An unusual side effect ot therapy with salicylazosulfapyridine. Chest 70:315–316

    Article  Google Scholar 

  • Cornbleet T, Hoit L, Sickley JF (1955) Fixed eruption. Arch Dermatol 71:507–510

    CAS  Google Scholar 

  • Corson EF, Sidlick DM (1922) Urticaria from habitual use of Phenolphthalein. JAMA 78:882–883

    Google Scholar 

  • Cumming WJK, Foster JB (1978) Cimetidine-induced brainsteam dysfunction. Lancet 1:1096

    Article  PubMed  CAS  Google Scholar 

  • Das KM, Dubin R (1976) Clinical pharmacokinetics of sulphasalazine. Clin Pharmacokinet 1:406–425

    Article  PubMed  CAS  Google Scholar 

  • Davies D, MacFarlane A (1974) Fibrosing alveolitis and treatment with sulphasalazine. Gut 15:185–188

    Article  PubMed  CAS  Google Scholar 

  • Delaunois L (1978) Hypersensitivity to Cimetidine. N Engl J Med 300:1216

    Google Scholar 

  • Doepfmer R (1954) Zur Kenntnis des perianalen Istizin-Erythems. Hautarzt 5:278–279

    PubMed  CAS  Google Scholar 

  • Domar M, Juhlin L (1967) Allergic dermatitis produced by oral clioquinol. Lancet 1:1165–1166

    Article  PubMed  CAS  Google Scholar 

  • Ekelund AG, Möller H (1969) Oral provocation in eczematous contact allergy to neomycin and hydroxy-quinolines. Acta Derm Venereol (Stockh) 49:422–426

    CAS  Google Scholar 

  • Feinberg SM (1935) Karaya gum asthma. JAMA 105:505

    Google Scholar 

  • Figley KD (1940) Karaya gum (Indian gum) hypersensitivity. JAMA 114:747–748

    Google Scholar 

  • Fox H (1918) Erythema perstans following ingestion of Phenolphthalein. J Cutan Dis 36:252–253

    Google Scholar 

  • Freston JW (1979) Cimetidine and granulocytopenia. Ann Intern Med 90:264–265

    PubMed  CAS  Google Scholar 

  • Gelfand HH (1943) The allergenic properties of the vegetable gums. A case of asthma due to tragacanth. J Allergy 14:203–219

    Article  CAS  Google Scholar 

  • Griffiths JD, Kane SP (1977) Sulphasalazine-induced lupus syndrome in ulcerative colitis. Br Med J 2:1188–1189

    Article  PubMed  CAS  Google Scholar 

  • Harpey JP, Caille B, Moulias R, Goust JM (1972) Drug allergy and lupus-like syndrome (with special reference to d-penicillamine). In: Dash CH, Jones HEH (eds) Mechanisms in drug allergy. Churchill Livingstone, Edinburgh London, pp 51–57

    Google Scholar 

  • Idvall J (1979) Cimetidine-associated thrombocytopenia. Lancet 2:159

    Article  PubMed  CAS  Google Scholar 

  • Ippen H (1959) Ätiologie und Pathogenese des sogenannten Istizin-Exanthemes. Dtsch Med Wochenschr 84:1062–1066

    Article  PubMed  CAS  Google Scholar 

  • Isenberg JI, Goldstein H, Korn AR, Ozeran RS, Rosen V (1968) Pulmonary vasculitis — an uncommon complication of ulcerative colitis. N Engl J Med 279:1376–1377

    Article  PubMed  CAS  Google Scholar 

  • Jaup H (1978) Salazosulfapyridin-induziertes Lupus-erythematodes-Syndrom bei Colitis ulcerosa. Dtsch Med Wochenschr 103:1211–1213

    Article  PubMed  CAS  Google Scholar 

  • Kandil E (1969) Fixed drug eruptions. Dermatologica 139:37

    Article  PubMed  CAS  Google Scholar 

  • Kauppinen K (1972) Cutaneous reactions to drugs. Acta Derm Venereol (Stockh) [Suppl] 52:68

    Google Scholar 

  • Kendall AC (1954) Fatal case of encephalitis after Phenolphthalein ingestion. Br Med J 2:1461–1462

    Article  PubMed  CAS  Google Scholar 

  • Kirschbaum HM (1942) Scopolamine in obstetrics. Am J Obstet Gynecol 44:664–672

    Google Scholar 

  • Klotz SA, Kay BF (1978) Cimetidine and agranulocytosis. Ann Intern Med 88:579

    PubMed  CAS  Google Scholar 

  • Lange K (1978) Nephropathy induced by D-penicillamine. Contrib Nephrol 10:63–74

    PubMed  CAS  Google Scholar 

  • Leifer W, Steiner K (1951) Studies in sensitization to halogenated hydroxy-quinolines and related compounds. J Invest Dermatol 17:233–240

    PubMed  CAS  Google Scholar 

  • Levi AJ, Fisher AM, Hughs L, Hendry WF (1979) Male infertility to sulphasalazine. Lancet 2:276–277

    Article  PubMed  CAS  Google Scholar 

  • Lindemayr W (1959) Arzneiexantheme. Dermatol Venerol 3/1:327–383

    Google Scholar 

  • Machado L, Zetterström O, Fagerberg E (1979) Occupational allergy in nurses to a bulk laxative. Allergy 34:51–55

    Article  PubMed  CAS  Google Scholar 

  • Matanic V (1956) L’urticaire provoquée par l’atropine avec fin létale. Int Arch Allergy 8:262–270

    Article  Google Scholar 

  • Mayer EC (1949) Edema of the uvula, a manifestation of scopolamine sensitivity. Calif Med 71:146–147

    PubMed  Google Scholar 

  • McDaniel JL, Stein JJ (1979) Thrombocytopenia with Cimetidine therapy. N Engl J Med 300:864

    PubMed  CAS  Google Scholar 

  • Meyboom RHB (1975) Heavy metal antagonists. In: Dukes MNG (ed) Meyler’s side effects of drugs, 8. Excerpta Medica, Amsterdam London New York, pp 529–542

    Google Scholar 

  • Mihas AA, Goldenberg DJ, Slaughter RL (1978) Sulfasalazine toxic reactions. Hepatitis, fever and skin rash with hypocomplementemia and immune complexes. JAMA 239:2590–2591

    Article  PubMed  CAS  Google Scholar 

  • Miller B (1977) Wirkung und Nebenwirkungen der Therapie mit Salizylazosulfapyridin. In: Kremer K, Kivelitz H (eds) Colitis ulcerosa. Thieme, Stuttgart, pp 71–86

    Google Scholar 

  • Nisticò G, Rotiroti D, de Sarro A, Naccari F (1978) Mechanism of cimetidine-induced fever. Lancet 2:265–266

    Article  PubMed  Google Scholar 

  • Pearson AJG, Grainger JM, Scheuer PJ, McIntyre N (1971) Jaundice due to oxyphenisatin. Lancet 1:994–996

    Article  PubMed  CAS  Google Scholar 

  • Phillipps FA (1932) Toxic effects of Phenolphthalein. Lancet 1:803

    Article  Google Scholar 

  • Pirilä V, Rantanen A (1960) Root canal treatment with bacitracinneomycin as cause of flare-up of allergic eczema. Oral Surg 13:589–593

    Article  PubMed  Google Scholar 

  • Posnett DN, Stein RS, Graber SE, Krantz SB (1979) Cimetidine-induced neutropenia. A possible dose related phenomenon. Arch Intern Med 139:584–586

    Article  PubMed  CAS  Google Scholar 

  • Primack WA (1978) Cimetidine and renal-allograft rejection. Lancet 1:824–825

    Article  PubMed  CAS  Google Scholar 

  • Reynolds TB, Peters RL, Yamade S (1971) Chronic active and lupoid hepatitis caused by a laxative, oxyphenisation. N Engl J Med 285:813–820

    Article  PubMed  CAS  Google Scholar 

  • Sakula A (1977) Bronchial asthma due to allergy to pancreatic extract. Lancet 2:193

    Article  PubMed  CAS  Google Scholar 

  • Sharpe PC, Hawkins BW (1977) Efficacy and safety of Cimetidine. Long-term treatment with Cimetidine. In: Burland WL, Simkins MA (eds) Cimetidine. Proc Second Int Symp on Histamine H2-receptor Antagonists. Excerpta Medica, Amsterdam London New York, pp 358–366

    Google Scholar 

  • Shelley WB, Schlappner OLA, Heiss HB (1972) Demonstration of intercellular immunofluorescence and epidermal hysteresis in bullous fixed drug eruption due to Phenolphthalein. Br J Dermatol 86:118–125

    Article  PubMed  CAS  Google Scholar 

  • Sotolongo RP, Neefe LI, Rudzki C, Ishak KG (1978) Hypersensitivity reaction to sulfasalazine with severe hepatotoxicity. Gastroenterology 75:95–99

    PubMed  CAS  Google Scholar 

  • Steinberg M (1945) Edema of the uvula and glottis; a reaction to demerol-scopolamine anesthesia. Am J Obstet Gynecol 50:542–545

    Google Scholar 

  • Ström J (1969) Toxic epidermal necrolysis (Lyell’s syndrome). A report on four cases with three deaths. Scand J Infext Dis 1:209–216

    Google Scholar 

  • Ström J (1977) Aetiology of febrile mucocutaneous syndromes with special reference to the provocative role of infections and drugs. Acta Med Scand 201:131–136

    Article  PubMed  Google Scholar 

  • Trimble WB (1909) Purpura. J Cutan Dis 27:306

    Google Scholar 

  • Tydd TF (1976) Sulphasalazine lung. Med J Aust 1:570–573

    PubMed  CAS  Google Scholar 

  • Vámossy Z (1902) Ãœber ein neues Abführmittel (Purgen). Ther Ggw 4:201–202

    Google Scholar 

  • Várkonyi V, Török I (1976) Salazopyrin okozta Lyell-syndroma. Orv Hetil 117:971–973

    PubMed  Google Scholar 

  • Villeneuve JP, Warner HA (1979) Cimetidine hepatitis. Gastroenterology 77:143–144

    PubMed  CAS  Google Scholar 

  • Wallace IW (1970) Neurotoxicity associated with a reaction to sulphasalazine. Practitioner 204:850–851

    PubMed  CAS  Google Scholar 

  • Welsh AL (1961) The fixed eruption. A possible hazard of modern drug therapy. Thomas, Springfield

    Google Scholar 

  • Werlin SL, Grand RJ (1978) Bloody diarrhea — a new complication of sulfasalazine. J Pediatr 92:450–451

    Article  PubMed  CAS  Google Scholar 

  • Westlin WF (1971) Desferoxamine as a chelating agent. Clin Toxicol 4:597–602

    Article  PubMed  CAS  Google Scholar 

  • Wile UJ (1936) Discussion case presentation. Arch Dermatol Syphilol 33:1089–1090

    Google Scholar 

  • Wise F, Sulzberger MB (1933) Drug eruptions. I. Fixed Phenolphthalein eruptions. Arch Dermatol Syphilol 27:549–567

    Google Scholar 

  • Wyatt E, Greaves M, Søndergaard J (1972) Fixed drug eruption (Phenolphthalein). Evidence for a blood born mediator. Arch Dermatol 106:671–673

    Article  PubMed  CAS  Google Scholar 

Download references

Authors
  1. L. Juhlin
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Institut für klinische Immunologie, Inselspital, CH-3010, Bern, Switzerland

    Alain L. de Weck

  2. Department of Pharmaceutical Chemistry AD, The Royal Danish School of Pharmacy, 2, Universitetsparken, DK-2100, Copenhagen, Denmark

    Hans Bundgaard

Rights and permissions

Reprints and permissions

Copyright information

© 1983 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Juhlin, L. (1983). Gastrointestinal Drugs. In: de Weck, A.L., Bundgaard, H. (eds) Allergic Reactions to Drugs. Handbook of Experimental Pharmacology, vol 63. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69088-4_21

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-69088-4_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-69090-7

  • Online ISBN: 978-3-642-69088-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation