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The Role of Complement in Phototoxic Reactions

  • Chapter
Immunodermatology

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Abstract

Light, in combination with selected drugs and chemicals, can produce two broad categories of cutaneous photosensitization, namely, photoallergic and phototoxic reactions [14]. Photoallergy is mediated by an immunologic mechanism and occurs in a small percentage of the exposed individuals. It fulfills the criteria for allergic sensitization with respect to induction, incubation period and reaction time [8]. Clinically, it is manifested as cutaneous erythema, edema and a papulovesicular eruption.

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Author information

Authors and Affiliations

  1. Departments of Dermatology and Medicine, Irvington House Institute, New York University Medical Center, New York, New York, 10016, USA

    Henry Lim

  2. Department of Dermatology, University of California, San Diego, University Hospital, 225 Bickinson Street, San Diego, CA, 92103, USA

    Irma Gigli

Authors
  1. Henry Lim
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  2. Irma Gigli
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Editor information

Editors and Affiliations

  1. Department of Dermatology, University of California, San Diego, University Hospital, 225 Bickinson Street, San Diego, CA, 92103, USA

    Irma N. Gigli

  2. Division d’Hématologie du Department de Médicine, Hôpital Cantonal, 25, rue Micheli-du Crest, CH-1211, Genève, Switzerland

    Peter A. Miescher

  3. Department of Molecular Immunology, Scripps Clinic and Research Foundation, 1066 North Torrey Pines Road, La Jolla, CA, 92037, USA

    Hans J. Müller-Eberhard

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© 1983 Springer-Verlag Berlin Heidelberg

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Lim, H., Gigli, I. (1983). The Role of Complement in Phototoxic Reactions. In: Gigli, I.N., Miescher, P.A., Müller-Eberhard, H.J. (eds) Immunodermatology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68702-0_9

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  • DOI: https://doi.org/10.1007/978-3-642-68702-0_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-11738-4

  • Online ISBN: 978-3-642-68702-0

  • eBook Packages: Springer Book Archive

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