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Pharmacokinetics of Squill Glycosides

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Cardiac Glycosides

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 56 / 2))

Abstract

Among the native squill glycosides, only proscillaridin A has so far found considerable clinical application. In addition, the semisynthetic meproscillarin (4’-methylproscillaridin A) was recently introduced. Pharmacokinetic knowledge of these glycosides has been obtained by indirect techniques based on clinical parameters and by measurements in plasma and other body fluids by use of 86Rb uptake inhibition assay or by 3 H-labeled glycosides. Generally, there is agreement between the results from the two approaches.

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© 1981 Springer-Verlag Berlin Heidelberg

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Andersson, KE., Bergdahl, B. (1981). Pharmacokinetics of Squill Glycosides. In: Greeff, K. (eds) Cardiac Glycosides. Handbook of Experimental Pharmacology, vol 56 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68166-0_4

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  • DOI: https://doi.org/10.1007/978-3-642-68166-0_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-68168-4

  • Online ISBN: 978-3-642-68166-0

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