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Bradykinin, Kallidin, and Kallikreins

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Bradykinin, Kallidin and Kallikrein

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 25 / 1))

Abstract

This article summarizes the results of investigations of various asepcts of the kallikrein-kinin system of blood plasma and tissues carried out by Soviet scientists. The chemistry, biochemistry, pharmacology, and physiology of kinins; the methods of study and estimation of activity of kinins and main components of the kallikreinkinin system; as well as the state of this system in healthy subjects and in patients are discussed. The summary deals with papers published in Soviet journals and monographs in the years 1970–1977. Only some of the works published earlier and not mentioned by Dr. Trĉka in Vol. XXV Handbook of Experimental Pharmacology are referred to.

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Abbreviations

AMe:

l-Arginine methyl ester

ATEe:

acetyl-l-tyrosine ethyl ester

ATP:

adenosine triphosphate

BAA:

benzoyl-l-argininamide

BAEe:

benzoyl-l-arginine ethyl ester

BAL:

2,3-dimercaptopropanol

BAMe:

bezoyl-l-arginine methyl ester

BANA:

benzoyl arginine-p-nitroanilide

BPP or BPF:

bradykinin-potentiating peptides

BPTI:

pancreatic trypsin inhibitor, aprotinin, Trasylol

CM:

carboxymethyl

CNS:

central nervous system

CSF:

cerebrospinal fluid

C-terminal:

carboxyl-terminal

CTI:

colostrum trypsin inhibitor

DEAE:

diethylaminoethyl

DFP:

diisopropylfluorophosphate

EACA:

ε-amino-n-caproic acid

EDTA:

ethylenediaminetetraacetate

FU:

Frey Unit for kallikrein

HF:

Hageman factor, factor XII

HLA:

hippuryl-l-arginine

HLAa:

hippuryl-l-argininic acid

HLL:

hippuryl-l-lysine

HMW:

high molecular weight

I50 :

concentration of inhibitor that inhibits 50% of enzyme activity

IU:

Inhibitor Unit, i.e, amount of inhibitor which inhibits cleanage of 1 μmol substrate

Kininase I, II:

See appendix

Kininogenase:

See appendix

K m :

Michaelis constant

LBTI:

Lima bean trypsin inhibitor

LMW:

low molecular weight

MW:

molecular weight

N-terminal:

amino terminal

OMTI:

ovomucoid trypsin inhibitor

PF/dil:

permeability factor

SBTI:

soybean trypsin inhibitor

SDS:

sodium dodecyl sulfate

Spec. act.:

specific activity

TAMe:

N-α-tosyl-l-arginine methyl ester

TCA:

trichloroacetic acid

TLCK:

1-chloro-3-tosylamido-7-amino-2-heptanone

TLMe:

N-α-tosyl-l-lysine methyl ester

Tris:

tris (hydroxymethyl) aminomethane

TPCK:

α-l-(1-tosylamido-2-phenyl) ethylchloromethyl ketone

U:

Unit of enzyme activity, i.e, amount of enzyme required to catalyze conversion of 1 μmol substrate/min

References

  • Andreyenko, G.V, Suvorov, A.V.: Deystvie plazmina na kallikreinogen. (Effect of plasmin on kallikreinogen.) Biokhimiia 41,557–561 (1976)

    Google Scholar 

  • Andrus, V.N.: Kininy plazmy krovi i patogeneticheskaya terapiya amidopirinom ostrogo pankreatita (Kinins of blood plasma and pathogenetic therapia of acute pancreatitis by amidopyrin). Klin. Khir. No. 5,52–53 (1969)

    CAS  Google Scholar 

  • Arkatov, V.A, Pekarskiy, D.E, Surovkina, M.S., Obuchov, Yu.E.: Svobodnye kininy i kininazy krovy v patologii ojogovoy bolezni (Free kinins and kininases in the plasma of patients with severe burns). In: Kininy i kininovaya sistema plasmy. Sbornik trudov 1 MMI im. Sechenova. Paskhina, T.S, Menshikov, V.V. (eds.), pp. 34–35. Published by 1 MMI im. Sechenova. Moskva 1976

    Google Scholar 

  • Barabash, R.D., Levitsky, A. P, Loginova, N. K, Vovchuk, S. V, Genesina, T. I, Konovets, V. M, Volodkina, V.V.: Rol kallikreina slyuny v patogeneze paradontoza (The role of saliva kallikrein in pathogenesis of paradonthosis). Vopr. Med. Khim. 22,318–325 (1976a)

    CAS  Google Scholar 

  • Barabash, R.D, Aleksandrov, P.N, Vovchuk, S. V.: Vliyanie kallikreinov slyuny na micrososudy zashchechnogo meshka khomyakov i bryjeyki krys (The influence of salivary kallikreins upon the microvessels of hamster cheek pouch and rat mesentery). Biul. Eksp. Biol. Med. 81, 782–785 (1976b)

    Google Scholar 

  • Belyakov, N. V, Syomushkin, B. V.: Registratsionnaya apparatura dlya biologicheskikh metodov opredeleniya nekotorykh tkanevykh gormonov (The recording equipment for bioassays of some tissue hormones). Lab. Delo No. 10,630–632 (1972)

    Google Scholar 

  • Belyakov, N. V, Syomushkin, B. V.: Superfuziya-apparatura i metod dlya opredeleniya nekotorykh komponentov kininovoy sistemy (Superfusion-the equipment and technique for estimation of some components of kinin system). In: Kininy i kininovaya sistema plasmy. Shornik Trudov 1 MMI im. Sechenova. Paskhina, T.S, Menshikov, V.V. (eds.), pp. 61–62. Moskva 1976 (Published by 1 MMI im Sechenova)

    Google Scholar 

  • Bondar, Z.A, Paskhina, T.S, Melkumova, I.S.: Soderjanie kininogena v syvorotke krovi bolnykh s zabolevaniami pecheni (The blood serum content of kininogen in patients with hepatic diseases). Lab. Delo No. 4,237–240 (1970)

    CAS  Google Scholar 

  • Chernova, N.A, Nekrasova, A.A.: Kallikrein mochi pri hipertonicheskoy bolezni i renovaskulyarnoy gipertonii (Urinary kallikrein in hypertensive vascular disease and renovascular hypertension). Kardiologiia 11, No. 4,84–89 (1971)

    CAS  PubMed  Google Scholar 

  • Chernova, N.A, Nekrasova, A.A, Lantsberg, L.A.: Osobennosti izmeneniy kininovoy sistemy krovi pri gipertonicheskoy bolezni (Peculiarities of changes in the kinin system of blood in cases of essential hypertension). Kardiologiia 16, No. 5,46–51 (1976)

    CAS  PubMed  Google Scholar 

  • Chernuch, A.M., Aleksandrov, P.N, Alekseev, O.V.: Microcirculatsiya (Microcirculation). Moskva: Medicina 1974

    Google Scholar 

  • Chernukh, A.M., Yarovaya, L.M, Glebov, R.N.: Vliyanie bradikinina na aktivnost Na, K-ATFasy mikrosom pochek i mozga krys (The effect of bradykinin on the activity of Na-K-ATPase of microsomes of the kidney and brain of rats). Biul. Eksp. Biol. Med. 78, No. 8, 50–52 (1974)

    CAS  PubMed  Google Scholar 

  • Chernukh, A.M., Gomazkov, O.A.: O regulatornoy i patogeneticheskoy roli kallikrein-kinin ovoy sistemy v organizme (On regulatory and pathogenetic function of kallikrein-kinin system in organism). Patol. Fisiol. Eksp. Ter. No. 1, 5–16 (1976)

    Google Scholar 

  • Dotsenko, V.L, Yarovaya, G.A, Golosova, N.A, Lebedeva, N.V, Orekhovich, V.N.: Vliyanie kininogena na aktivnost kininogenaznoy sistemy syvorotki krovi cheloveka (Effect of kininogen on the activity of human blood serum kininogenase system). Biokhimiia 42, 283–286 (1977)

    CAS  Google Scholar 

  • Dzizinsky, A. A, Kuimov, A.D.: Aktivnost kininovoy sistemy krovi pri ishemicheskoy bolezni serdtsa (The activity of the kinin system in cardiac ischemia). Kardiologia 11, No. 6, 18–22 (1971)

    Google Scholar 

  • Dzizinsky, A. A, Gomazkov, O.A.: Kininy v fiziologii i patologii serdechno-sosudistoy sistemy (Kinins in physiology and pathology of cardio-vascular system). Novosibirsk: Nauka 1976

    Google Scholar 

  • Egorova, T. P, Paskhina, T. S.: Ochistka kininogena (bradikininogena) iz plazmy krovi krolika i izuchenie iego svoistv [Purification of kininogen (bradykininogen) from rabbit blood plasma and study its properties]. Biokhimiia 32,354–362 (1967)

    CAS  PubMed  Google Scholar 

  • Egorova, T.P, Makarova, O.V, Paskhina, T.S.: Nekotorye svoystva i substratnaya priroda ochishchenogo kininogena krolika (Some properties and substrate nature of purified rabbit kininogen). Biokhimiia 34,610–619 (1969)

    CAS  PubMed  Google Scholar 

  • Egorova, T.P, Makevnina, L. G, Paskhina, T. S.: Aminokislotny sostav, osobennosti stroeniya i substratnaya specifichnost kininogena plazmy krolika (Amino acid composition, some features of structure and substrate specificity of rabbit plasma kininogen). Biokhimiia 40, 158–165 (1975)

    CAS  PubMed  Google Scholar 

  • Egorova, T. P, Eliseeva, Yu. E.: Deystvie karboksikatepsina na biologicheskuyu aktivnost bradikinina (Effect of carboxycathepsin on the biological activity of bradykinin). Vopr. Med. Khim. 22,119–122 (1976)

    CAS  PubMed  Google Scholar 

  • Egorova, T. P, Rossinskaya, E. B, Paskhina, T. S.: Ochistka i svoystva vysokomolekulyarnogo kininogena krolika (Purification and properties of high-molecular weight rabbit kininogen). Biokhimiia 41,1052–1060 (1976)

    CAS  PubMed  Google Scholar 

  • Eliseeva, Yu. E, Orekhovich, V. N.: Vydelenie i izuchenie spetsifichnosti karboxikatepsina (Isolation and investigation of carboxycathepsin specificity). Dokl. Akad. Nauk SSSR 153, 954–957 (1963)

    CAS  Google Scholar 

  • Eliseeva, Yu.E, Orekhovich, V.N, Pavlikhina, L.V, Alexeenko, L.P.: Karboxikatepsin-klyuchevoy ferment dvukh sistem, regulirujushchikh krovyanoe davlenie (Carboxycathepsin — a key regulatory component of two physiological system involved in regulation of blood pressure). Vopr. Med. Khim. 16,646–649 (1970)

    CAS  PubMed  Google Scholar 

  • Eliseeva, Yu.E, Orekhovich, V.N, Pavlikhina, L.V, Alexeenko, L.P.: Carboxycathepsin — a key regulatory component of two physiological systems involved in regulation of blood pressure. Clin. Chim. Acta 31,413–419 (1971)

    CAS  Google Scholar 

  • Eliseeva, Yu.E, Pavlikhina, L.V, Orekhovich, V.N.: Vydelenie karboxikatepsina (peptidil-dipeptidasy, KF. 3.4.15.1) iz pochek byka [Isolation of carboxycathepsin (peptidyl-diepeptidase EC. 3.4.15.1) from bovine kidney]. Dokl. Akad. Nauk SSSR 217,953–956 (1974)

    CAS  PubMed  Google Scholar 

  • Eliseeva, Yu.E, Orekhovich, V.N, Pavlikhina, L.V.: Svoystva i specifichnost karboxikatepsina (peptidil-dipeptidasy) iz pochek byka ]Properties and specificity of carboxycathepsin (peptidyl-dipeptidase) from bovine kidney]. Vopr. Med. Khim. 22, 81–89 (1976a)

    CAS  Google Scholar 

  • Eliseeva, Yu.E, Orekhovich, V.N, Pavlikhina, L.V.: Vydelenie i svoystva karboxikatepsina (peptidil-dipeptidasy) iz tkaney lyogkieh byka [Isolation and properties of carboxycathepsin (peptidyl-dipeptidase) from bovine lung]. Biokhimiia 41,506–512 (1976b)

    CAS  Google Scholar 

  • Filatova, M.P, Krit, N.A, Shchukina, G.S, Ravdel, G.A, Ivanov, V.T.: Novy sintez bradikinina i ego analogov (A new synthesis of bradykinin and its analogs). Bioorgan. Khim. 1,437–446 (1975)

    CAS  Google Scholar 

  • Gaponyuk, P.Ya, Umarkhodjaev, E.M.: Izmenenie kininovoy sistemy krovi pri ostroj luchevoy bolezni (Changes of the blood kinin system in acute radiation injury). Radiobiologiia 10, 681–684 (1970)

    CAS  Google Scholar 

  • Gaponyuk, P.Ya, Oyvin, V. I.: Sravnitelnoe izuchenie deystviya bradikinina, kallidina, metionillizil-bradikinina i eledoizina na pronizaemost sosudov koji (The comparative study of effects of bradykinin, kallidin, methionyl-lysyl-bradykinin and eledoisin on the vascular permeability). Biul. Eksp. Biol. Med. 71, No. 3,57–59 (1971a)

    CAS  Google Scholar 

  • Gaponyuk, P.Ya, Oyvin, V.I.: O neposredstvennom deystvii bradikinina na pronitsaemost sosudov (The direct effect of bradykinin on the vascular permeability). Biul. Eksp. Biol. Med. 71, No. 6,23–25 (1971b)

    Google Scholar 

  • Gaponyuk, P.Ya, Kalinkina, T.N, Gaponyuk, E.J.: Izmenenie koncentratsii svobodnykh kininov v krovi jivotnykh pri ostroy luchevoy bolezni (Changes of the concentration in the free kinin level in irradiated rats). Radiobiologiia 12,735–736 (1972a)

    CAS  Google Scholar 

  • Gaponyuk, P.Ya, Podsosov, S.P, Rudakov, I.A.: Vliyanie trazilola i soevogo inhibitora tripsina na vyjivaemost obluchennykh jivotnykh (The influence of trasylol and soy-bean inhibitor of trypsin, on the survival of irradiated animals). Radiobiologiia 12,927–928 (1972b)

    CAS  Google Scholar 

  • Gaponyuk, P.Ya, Uklonskaya, L.I.: Energeticheskie aspekty deystviya histamina i bradikinina na pronitsaemost sosudov (Energy aspects of histamine and bradykinin action on vascular permeability). Biul. Eksp. Biol. Med. 78, No. 10,18–20 (1974)

    CAS  Google Scholar 

  • Gaponyuk, P.Ya, Tsyb, A.F, Strigunov, V.I, Drozdovsky, B.Ya, Mannanov, I.S.: Vliyanie bradikinina na krovoobrashchenie v basseyne chrevnoy arterii cheloveka (The influence of bradykinin on the blood circulation in the reservoir of the celiac artery in man). Biul. Eksp. Biol. Med. 79, No. 6,14–16 (1975a)

    CAS  Google Scholar 

  • Gapanyuk, P.Ya, Strigunov, V.I, Tsvet, A.Ph, Mannakov, I.S, Drozdovskiy, B.Ja.: Metodika primeneniya bradikinina pri angiograficheskikh issledovaniyakh (The method of bradykinin using of angiographic examinations). Med. Radiobiologia 20, No. 8,6–10 (1975b)

    Google Scholar 

  • Gavrilova, R. D, Jurina, T. M.: Izmenenie kininovoy sistemy krovi i urovnya komplementa pri khronicheskoy pnevmonii (Changes of the kinin system of the blood and the level of complement in chronic pneumonia). Klin. Med. 52, No. 12,75–79 (1974)

    CAS  Google Scholar 

  • Geller, L.I, Amatnyan, A.G, Kobzev, V.S, Romanets, V.A.: Kliniko-farmakologicheskoe izuchenie kininov v gastroeneterologii (Clinical and pharmacological aspects of investigation of kinins in gastroenterology). Vrach. Delo No. 4,85–88 (1972a)

    CAS  Google Scholar 

  • Geller, L.I, Ostrovsky, A.B, Kazimirchik, A.P, Amatnyan, A. G.: Svertyvayushchaya, protivosvertyvayushchaya i kininovaya sistema krovi pri obostrenii khronieheskogo pankreatita (Coagulation, anticoagulation and kinin systems of the blood in patients with chronic pancreatitis). Klin. Med. 50, No. 9,107–112 (1972b)

    CAS  Google Scholar 

  • Gigineishvili, M.S., Tsverava, E.N, Jikiya, J.B.: Sistema kininov pri fiziologicheskoy beremennosti (The kinin system in physiological pregnancy). Sabchota Medicine No. 4, 16–18 (1973)

    Google Scholar 

  • Golikov, A.P, Bobkov, A.I, Ivleva, V.I.: Nekotorye pokazateli kininovoy i simpatiko-adrenalovoy sistem u bolnykh povtornym infarktom miokarda (Some indices of the kinin and sympathoadrenal system in patients with repeated myocardial infarctions). Kardiologia 16, No. 2, 74–77 (1976)

    CAS  Google Scholar 

  • Gomazkov, O.A, Bolshakova, L.V, Shimkovich, M.V, Komissarova, N.V.: Izmenenie aktivnosti kallikrein-kininovoy sistemy pri ostroy ishemii miokarda v eksperimente (Changes in the activity of the kallikrein-kinin system in experimental acute ischemia of the myocardium). Kardiologia 12, No. 4,22–28 (1972a)

    CAS  Google Scholar 

  • Gomazkov, O.A, Komissarova, N.V, Bolshakova, L.V, Teplova, N.N.: Metodicheskie podkhody k isucheniju kallikrein-kininovoy sistemy pri infarkte miokarda (Methodological approaches to the study of kallikrein-kinin system in myocardial infarction). Kardiologia 12, No. 6,25–31 (1972b)

    Google Scholar 

  • Gomazkov, O. A.: Kallikrein-kininovaya sistema krovi i regulatciya hemodinamiki. Obzor (Kallikrein-kinine system and regulation of hemodynamics. Review). Kardiologia 13, No. 7,130–144 (1973)

    CAS  Google Scholar 

  • Gomazkov, O.A, Komissarova, N.V, B olshakova, L.V, Shimkovich, M.V.: Aktivatsiya kallikreina i uroven kininogenov v venoznoy i arterialnoy krovi krys pri ostroy ishemii miokarda (Activation of kallikrein and the level of kininogens in the venous and arterial blood of rats in acute myocardial ischemia). Biul. Eksp. Biol. Med. 76, No. 8,25–27 (1973)

    CAS  PubMed  Google Scholar 

  • Gomazkov, O.A.: Das Kallikrein-SystembeiMyokardischamie und Herzinfarkt. Med. Welt. 25, 804–807 (1974)

    CAS  PubMed  Google Scholar 

  • Gomazkov, O.A, Shimkovich, M.V.: Izmenenie depressornyeh otvetov na bradikinin preparatami blokirujushchimi kininazu i adrenoretseptory (Changes of depressor response to bradykinine by using preparations blocking kininase and agrenoreceptors). Kardiologia 14, No. 7, 57–65 (1974)

    CAS  Google Scholar 

  • Gomazkov, O.A, Shimkovich, M.V.: Tsiprogeptadin kak ingibitor effektov bradikinina (Ciproheptadin as an inhibitor of the bradykinin effects). Biul. Eksp. Biol. Med. 80, No. 7, 6–9 (1975)

    CAS  PubMed  Google Scholar 

  • Gomazkov, O.A, Komissarova, N.V.: Obshchie mekhanizmy biokhimicheskoy regulatsii kallikreinovoy, svertyvayushchey i fibrinoliticheskoy sistem krovi (Several mechanisms of biochemical regulation of kallikrein, coagulation and fibrinolytic systems of blood). Usp. Sovrem. Biol. 82, 356–370 (1976a)

    CAS  Google Scholar 

  • Gomazkov, O.A, Komissarova, N.V.: Metod odnovremennogo opredeleniya predshestvennikov kallikreina, plazmina, trombina i ikh inhibitorov v plazme krovi cheloveka (Method of simultaneous determination of precursors of kallikrein, plasmin, thrombin, and their inhibitors in human blood plasma). Biul. Eksp. Biol. Med. 81,632–633 (1976b)

    CAS  Google Scholar 

  • Ivashkevich, G.A, Vuiv, G.P, Khimka, A.S.: Issledovanie nekotorykh komponentov kininovoy sistemy pri ostrykh gnoynykh peritonitakh (The investigation of some components of kinin system in acute suppurative peritonitis). Vestn. Khir. 116, No. 4,14–18 (1976)

    CAS  PubMed  Google Scholar 

  • Kauricheva, N.I, Budnitskaya, P.Z, Bogomolets-Henriques, O.M.: Vydelenie i nekotorye svoystva dvukh kininogenov plasmy krovi loshadi (Isolation and some properties of two kininogens from horse plasma). Vopr. Med. Khim. 17,6–12 (1971)

    CAS  PubMed  Google Scholar 

  • Khodorov, B.I, Timin, E.N, Pogadaev, V.L: Rol khemovozbudimykh kalcievykh kanalov v mekhanizme deystviya acetilkholina, histamina i bradikinina na depolyarizovannuyu gladkuyu myshtsu (The role of chemoexcitive calcic canals in mechanism of action of acetylcholine, histamine, and bradykinin on depolarized smooth muscle. In: Physiologia and biokhimiya mediatornich processov. Thesis Dokl. Vsesoyuzn. Konf, Posvyashch. 75-letiyu so dnya rojd. Kh. S. Koshtoyantsa. Turpaev, T.M. (ed.), pp. 133–134. Moskva: 1976 (Published by Akad. Sei. USSR)

    Google Scholar 

  • Khutzurauli, E. Sh, Tsverava, E. N.: Bradikininogen i aktivnost kininaz plazmy krovi pri khronicheskom mieloleykoze (Bradykininogen and kininase activity of blood plasma in patients with chronic myeloleukemia). Sakartvelos SSR. Metsnierebata Akademine moamte, Soobtch. AN Gruz. SSR. 74,697–699 (1974)

    Google Scholar 

  • Komissarova, N.V, Gomazkov, O.A.: Osobennosti kontaktnoy aktivatsii kallikreinovoy i plasminovoy sistem krovi krolika (Some features of contact activation of the kallikreine and plasmin systems of rabbit blood). Biul. Eksp. Biol. Med. 81,390–392 (1976)

    CAS  PubMed  Google Scholar 

  • Kotelnikov, V. P, Pankov, V. I.: Svobodnye kininy krovi u khirurgicheskikh bolnykh (Free blood kinins in surgical patients). Khirurgiia No. 11,137–140 (1976)

    Google Scholar 

  • Krit, N.A, Ravdel, G.A, Ivanov, V.T.: Sintez analogow bradikinina, modificirovannykh v polojenii 8 (Synthesis of bradykinin analogs modified in position “8”). Bioorgan. Khim. 2, 1455–1463 (1976)

    CAS  Google Scholar 

  • Kraynova, B. L, Kiporenko, S. S, Chaman, E. S.: Sintez o-gippuril-δ-guanidino-α-l-oxivalerianovoy kisloty (o-gippuril-l-argininovoy kisloty) [Synthesis o-hippuryl-δ-guonidino-α-l-oxyvalerianic acid (o-hippuryl-l-argininic acid)]. Zh. Obshch. Khim. 40, 708–709 (1970)

    Google Scholar 

  • Kuzin, M.I, Menshikov, V.V, Dudnik, V.S, Beljakov, N.V.: Kininovaya sistema i eyo uchastie v patogeneze nekotorykh khirurgicheskikh zabolevaniy (obzor literatury) [Kinin system and its participation in pathogenesis of some surgical diseases (Review)]. Khirurgiia No. 2, 116–120 (1974)

    Google Scholar 

  • Lakin, K.M, Rachitskaya, N.G, Polonskaya, L.B.: Inhibitor fibrinoliza iz legochnoy tkani — inhitril (Inhitryl — a fibrinolysis inhibitor prepared from the pulmonary tissue). Farmakol. Toksikol. 35,320–324(1972)

    CAS  PubMed  Google Scholar 

  • Lantsberg, L.A, Nekrasova, A.A.: Ob uchastii kininovoy sistemy pochek i krovi v adaptatsii organisma k fizicheskim nagruzkam (On the participation of the kinin system of kidneys and blood in adaptation of the body to physical stress). Kardiologia 12, No. 9, 58–63 (1972)

    CAS  Google Scholar 

  • Lantsberg, L.A, Kutyrina, I.M, Nekrasova, A.A, Chernova, N.A.: Rol kininovoy sistemy pochek v regulatsii natriy-uresa (The role of kinin system of kidneys in regulation of sodium excretion). Vestn. Acad. Med. Nauk SSSR No. 10, 51–54 (1974)

    Google Scholar 

  • Laufer, A.L, Gulikova, O.M, Paskhina, T.S.: O dvukh kininoobrayushchikh fermentakh plazmy krovi cheloveka (Two kinin-producing enzymes of human blood plasma). Biokhimiia 34,3–12 (1969)

    CAS  PubMed  Google Scholar 

  • Levitsky, A.P, Konovets, V.M, Lvov, I.F, Barabash, R.D, Volodkina, V.V.: Kallikrein i nespetcificheskie proteazy v slyune bolnykh yazvennoy boleznyu jeludka i dvenadtsatiperstnoy kishki (Alterations in activities of kallikrein and nonspecific proteases in human saliva in ulcerous disease of stomach and duodenum). Vopr. Med. Khim. 19,633–638 (1973)

    Google Scholar 

  • Levitsky, A.P, Vovchuk, S.V.: Raspredelenie v pishchevaritelnoy sisteme krys proteoliticheskogo fermenta slyuny-salivaina (Distribution of a proteolytic enzyme in the saliva-salivain in the digestive system of rats). Biul. Eksp. Biol. Med. No. 712–24 (1973)

    Google Scholar 

  • Levitsky, A.P, Vovchuk, S.V, Barabash, R.D.: Obnarushenie, vydelenie i svoystva kallikreina slyuny krysy i zolotistogo khomyaka (The detection, purification, and properties of salivary kallikrein in the golden hamster citellus auratus and in rats). Zh. Evol. Biokhim. Fisiol. 10, 510–512 (1974)

    Google Scholar 

  • Lokshina, L. A, Egorova, T. P, Orekhovich, V. N.: Proteinazy v selezenke byka s kininogenaznoy aktivnostju (Proteinase in bovine spleen with kininogenase activity). Biokhimiia 41, 2021–2024 (1976)

    CAS  PubMed  Google Scholar 

  • Lyublinskaya, L.A, Vaganova, T.I, Paskhina, T.S, Stepanov, V.M.: 2,4-dinitrofenil-proizvodnye peptidov — substraty novogo tipa dlya opredeleniya aktivnosti proteoliticheskikh fermentov. Opredelenie aktivnosti karboksipeptidaz (2,4-dinitrophenyl-derivatives of peptidessubstrates of a new type for determination of activity of proteolytic enzymes. Determination of carboxypeptidase activity). Biokhimiia 38,790–795 (1973)

    CAS  Google Scholar 

  • Malaya, L.T, Berkelieva, S.Ch, Lazareva, S.A.: Aktivnost kininogenazy i kininazy pri infarkte miokarda i kardiogennom shoke (The activity of kininogenase and kininase in myocardial infarction and cardiogenic shock). Vestn. Acad. Med. Nauk SSSR No. 3, 30–40 (1973a)

    Google Scholar 

  • Malaya, L.T, Lazareva, S.A, Berkelieva, S.Ch.: Aktivnost kininogen-kininovoy sistemy pri ostrom krupnoochagovom infarkte miokarda i ego oslojneniyakh (Kininogen-kinin system in acute macrofocal myocardial infarction and its complications). Klin. Med. 55, No. 4,29–36 (1973b)

    Google Scholar 

  • Malaya, L.T, Lazareva, S.A.: Znachenie aktivatsii kallikrein-kininovoy sistemy dlya diagnostiki infarkta miokarda i naibolee tyajolykh ego oslojneniy (The significance of kallikrein-kinine systeme activation for the diagnostic of myocardial infarction and its severe complications). In: Kinins and kinin systems of blood. Trudy I MMI im. Sechenova. Paskhina, T. S, Menshikov, V.V. (eds.), pp. 68–69. Moskva: 1976 (Published by 1 MMI im Sechenova.)

    Google Scholar 

  • Mashkovsky, M.D, Lakin, K. M, Ovnatanova, M. S, Schwartz, G. Ya.: Vlijanie parmidina (piridinolkarbamata) na agregatsiyu trombocitov, svertyvanie krovi i fibrinoliz [The effect of parmidine (pyridinolcarbamate) on the platelet aggregation, blood coagulation and fibrinolysis]. Biul. Eksp. Biol. Med. 81,322–324 (1976)

    Google Scholar 

  • Meerson, F.Z, Gomazkov, O.A, Shimkovich, M.V, Bolshakova, L.V.: Znachenie sistemy kininov dlya regulatsii krovoobrashcheniya pri adaptatsii k vysotnoy hipoksii (Significance of the kinin system for regulation of blood circulation during adaptation to high altitude hypoxia). Kardiologia 14, No. 6, 38–45 (1974)

    CAS  Google Scholar 

  • Meged, N.F, Veremienko, K.M, Pavlof, V.V, Tertykh, V.A.: Activation of blood plasma prekallikrein by high-dispered organic silica. Ukr. Biokhim. Zh. 48,370–374 (1976)

    CAS  PubMed  Google Scholar 

  • Menshikov, V.V, Orlov, V.A, Belyakov, N.V.: Kininovaya sistema krovi v gastroenterologii (biokhimiya i fiziologiya, klinicheskoe znachenie) [Kinin system of blood in gastroenterology (biochemistry, physiology and clinical importance)]. Klin. Med. 50, No. 1, 12–19 (1972)

    CAS  Google Scholar 

  • Narticova, V. F, Paskhina, T. S.: Ochistka i svoystva kislotostabilnogo ingibitora iz syvorotki krovi krolika (Purification and characteristics of an acid-resistant inhibitor of trypsin from rabbit blood serum). Biokhimiia 34,282–292 (1969)

    Google Scholar 

  • Nekrasova, A.A, Lantsberg, L.A, Chernova, N.A, Khukharev, V.V.: Kininovaya sistema pochek pri razlichnykh fiziologicheskykh sostoyaniyakh u zdorovykh lyudey i pri hipertonicheskoy bolezni (The kinine system of the kidneys in different physiological conditions in healthy persons and in patients with hypertensive vascular disease). Kardiologia 10, No. 11, 9–25 (1970)

    CAS  Google Scholar 

  • Nekrasova, A. A, Khukharev, V.V.: Kininovaya sistema pochek u bolnykh hipertonicheskoy boleznyu i ego vozmojnaya kompensatornaya rol v regulatsii pochechnogo krovotoka (Renal kinin system in patients with hypertensive disease and its possible compensatory role in the regulation of renal blood flow). Kardioloia 12, No. 7,14–19 (1972)

    CAS  Google Scholar 

  • Nekrasova, A.A, Chernova, N.A, Lantsberg, L.A, Khukharev, V.V.: Kininovaya sistema pochek, metody opredeleniya ego osnovnykh komponentov — kallikreina i kininov v moche (Renal kinin system, methods of determination of the main components in urine-kallikrein and kinins). Lab. Delo No. 4,223–228 (1972)

    CAS  Google Scholar 

  • Nekrasova, A.A, Lantsberg, L.A, Kramer, A.A, Eventov, A.Z.: Sostoyanie kininovoy sistemy krovi u bolnykh hipertonicheskoy boleznyu (Blood kinin system in patients with hypertensive disease). Sov. Med. No. 3,28–33 (1973)

    Google Scholar 

  • Obukhov, Yu. E.: Svobodnye kininy krovi v dinamike ojogovoy bolezni (Free plasma kinines in burn). In: Ojogovaya bolezn (Burn disease). Postyanoi, N.F. (ed.), pp. 70–72. Kiev: Zdorovie 1975

    Google Scholar 

  • Orekhovich, V.N.: Properties, specificity and mechanism of action of the proteolytic enzymes. Ital. J. Biochemistry 17,241–256 (1968)

    CAS  Google Scholar 

  • Orekhovich, V.N, Eliseeva, Yu.E, Pavlikhina, L.V, Negovskiy, V.A, Molchanov, L.V.: Fermentativnye osnovy regulyatsii sosudistogo tonusa pri ekstremalnykh sostoyaniyakh (Enzymatic basis of vascular tonus regulation in extrema states). Fisiologiya Cheloveka 1, 310–316 (1975)

    CAS  Google Scholar 

  • Orekhovich, V.N, Eliseeva, Yu.E, Pavlikhina, L.V.: Enzimologicheskie faktory regulatsii sosudistogo tonusa (Enzymological factors in the vascular tension regulation). Vestn. Aksd. Med. Nauk SSSR 9,42–47(1976)

    Google Scholar 

  • Orekhovich, V. N.: Sovremennye metody v biokhimii (Modern methods in biochemistry). Orekhovich, V.N. (ed.), Vol. 3. Moskva: Medicina 1977

    Google Scholar 

  • Oyvin, I.A, Gaponyuk, P.Ya, Oyvin, V.I, Tokarev, O.Yu.: The mechanism of blood vessel permeability derangement under the influence of histamine, serotonin, and bradykinin. Experientia 26,843–844 (1970)

    CAS  PubMed  Google Scholar 

  • Oyvin, I.A, Gaponyuk, P.Ya, Oyvin, V.I, Tokarev, O.Yu, Volodin, V.M.: Mekhanizmy povysheniya pronitsaemosti sosudov pod vliyaniem faktorov pronitsaemosti (histamin, serotonin, bradikinin) i vospalitelnykh razdrajiteley [Mechanisms involved in increasing the vascular permeability under the effect of permeability factors (histamine, serotonin, kinins) and of inflammatory agents]. Patol. Fiziol. Eksp. Ter. No. 4,19–23 (1972a)

    Google Scholar 

  • Oyvin, I.A, Gaponyuk, P.Ya, Uklonskaya, L.I.: K mekhanizmu povysheniya pronitaaemosti sosudov kozhi pri mestnov-obluchenii (On the mechanism of the increased permeability of cutaneous vessels at local-irradiation of skin). Radiobiologiia 12,462–463 (1972b)

    Google Scholar 

  • Oyvin, I.A, Gaponyuk, P.Ya, Uklonskaya, L.I.: Aktualnye voprosy patogeneza i terapii ostrogo vospaleniya (Obzor) [Important problems of pathogenesis and therapy of accute inflammation (Review)]. Patol. Fiziol. Eksp. Ter. No. 2,3–10 (1973)

    Google Scholar 

  • Paskhina, T.S.: Mechanism obrasovaniya, obmen i rol pri sosudistych patologiyach kininov plasmi krovi (The mechanism of formation, methabolism, and role at the cardio-vascular patology). In: Molecularnii osnovi patologii. Orechovich, zN. (ed.), pp. 123–178. Moskva: Medicina 1966

    Google Scholar 

  • Paskhina, T.S, Egorova, T.P.: Ochistka i svoystva kininogena (bradikininagena) iz syvorotki krovi krolika [Purification and properties of kininogen (bradykininogen) of rabbit blood serum]. Biokhimiya 37,468–476 (1966)

    Google Scholar 

  • Paskhina, T.S, Zykova, V.P, Egorova, T.P, Narticova, V.F, Karpova, A.V, Guseva, M.V.: Reactsiya N-α-tozyl-l-lisilkhlormetan s kallikreinom iz plasmy krolika i s kallikreinom iz mochi i slyuny cheloveka (Reaction of N-α-tozyl-l-lysilchlormethane with kallikrein from rabbit plasma and with kallikrein from urine and saliva of man). Biokhimiia 33, 745–752 (1968a)

    CAS  Google Scholar 

  • Paskhina, T. S, Gulikova, O. M, Egorova, T. P, Surovikina, M. S, Shmyryova, R. K.: Opredeleniye bradikinina pri pomoshchi biologicheskykh i khromatograficheskikh metodov (Estimation of bradykinin by biochemical and chromatographic methods). In: Sovremennye metody v biokhimii (Modern methods in biochemistry). Orekhovich, V.N. (ed.), pp. 205–232. Moskva: Medicina 1968b

    Google Scholar 

  • Paskhina, T.S, Egorova, T.P, Zykova, V.P, Laufer, A.L, Trapeznikova, S.S, Shimonaeva, E. E.: Khimicheskie i biologicheskie metody opredeleniya osnovnykh komponentov kininovoy sistemy krovi (kininogena, kallikreina, ingibitorov kallikreina, kininasy) [Chemical and biological methods for estimation of main components of kinin system of blood (kininogen, kallikrein, kallikrein inhibitors, kininase)]. In: Sovremennye metody v biokhimii (Modern methods in biochemistry). Orekhovich, V.N. (ed.), Vol. 2, pp. 232–261. Moskva: Medicina 1968c

    Google Scholar 

  • Paskhina, T. S.: Fermentativny mekhanizm obrazovaniya i raspada kininov plazmy krovi bradikinina i kallidina (Enzymatic mechanism of formation and decomposition of blood plasma kinins — bradikinin and kallidin). In: Chemical factors of enzymatic activity and biosynthesis regulation. Orechovich, V.N. (ed.), pp. 317–359. Moscow: Medicina 1969

    Google Scholar 

  • Paskhina, T.S, Yarovaya, G.A.: Kallikrein syvorotki krovi cheloveka. Aktivnost fermenta i khromatograficheskiy metod opredeleniya (Kallikrein of the serum of human blood. Enzyme activity and chromatographic method for its determination). Biokhimiia 35, 1055–1058 (1970a)

    CAS  Google Scholar 

  • Paskhina, T.S, Yarovaya, G.A, Laufer, A.L, Gulikova, O.M, Trapeznikova, S.S, Morozova, N.A, Makarova, O.V, Tikhomirov, LB, Sysoyev, V.F, Match, E.S.: Soderjanie i aktivnost osnovnykh komponentov kininovoy sistemy v syvorotke krovi bolnykh revmatismom (The content and activity of basic components of kinin system in blood serum of patients with rheumatism). Vopr. Med. Khim. 16,152–161 (1970b)

    CAS  Google Scholar 

  • Paskhina, T.S.: Enzymatichesky mekhanism obrazovaniya i raspada kininov (Enzymatic mechanism of formation and destruction of kinins). In: Sovremenniye problemy endocrinologii. Judaev, N.A. (ed.), Vol. 4, pp. 108–122. Moskva: Medicina 1972

    Google Scholar 

  • Paskhina, T.S, Shrayber, M.I, Yarovaya, G.A, Morozova, N.A, Nartikova, V.F, Trapeznikova, S.S, Docenko, V.L, Makarova, O.V, Maslova, T.M.: Rol kininovoy sistemy v patogeneze ojogovoy bolezny cheloveka. I. Sostoyanie kininovoy sistemy v razlichnye periody ojogovoy bolezny (Role of kinin system in pathogenesis of burn disease. I. State of kinin system in different periods of burn disease). Vopr. Med. Khim. 18,137–145 (1972)

    CAS  Google Scholar 

  • Paskhina, T.S, Gurtovenko, V. M.: Vliyanie stekla i ellagovoy kisloty na obrazovanie kininov v plazme krovi krolika (Effects of glass and ellagic acid on formation of kinins in rabbit blood plasma). Vopr. Med. Khim. 27,7–15 (1972)

    Google Scholar 

  • Paskhina, T.S, Dotsenko, V.L, Blinnikova, E.L: Kallikreinogen syvorotki krovi cheloveka. Metod opredeleniya i nekotorye svoystva (Kallikreinogen in human blood serum; a method of estimation and some properties). Biokhimiia 38,420–423 (1973)

    CAS  PubMed  Google Scholar 

  • Paskhina, T.S, Krinskaya, A.V.: Uproshchenny metod opredeleniya kallikreinogena i kallikreina v syvorotke (plazme) krovi cheloveka v norme i pri nekotorykh patologicheskikh sostoyaniyakh (A simplified method for determination of kallikreinogene and kallikrein in human blood serum in normal and some pathological states). Vopr. Med. Khim. 20, 660–666 (1974)

    CAS  PubMed  Google Scholar 

  • Paskhina, T.S, Krinskaya, A.V, Zykova, V.P.: Deystvie ingibitorov tripsina peptidno-belkovoy prirody na kallikreiny syvorotki krovi cheloveka i krolika (Effect of trypsin inhibitor of a peptide-protein nature on kallikreins from human and rabbit blood serum). Biokhimiia 40, 302–309 (1975a)

    CAS  Google Scholar 

  • Paskhina, T.S, Trapeznikova, S.S, Egorova, T.P, Morozova, N.A.: Vlijanie bradikinin potents iruyushchikh peptidov zmeinogo yada i C-koncevogo pentapeptidnogo fragmenta bradikinina na aktivnost karboksipeptidazy N i kininaznuyu aktivnost syvorotky krovi cheloveka (Effect of bradikinin-potentiating snake venom peptides and C-terminal pentapeptide fragment of bradykinin on carboxypeptidase N and kininase activities of human blood serum). Biokhimiia 40,844–852 (1975b)

    CAS  Google Scholar 

  • Paskhina, T.S, Bondar, Z.A, Krinskaya, A.V, Melkumova, I.S, Polikarpova, E.G.: Sostoyanie kallikreinogen-kallikreinovoy sistemy u bolnykh s zabolevaniyami pecheni (State of kallikreinogen-kallikrein system in patients with hepatic diseases). Klin. Med. 53, No. 8, 9–15 (1975c)

    CAS  Google Scholar 

  • Paskhina, T.S, Menshikov, V.V. (eds.): Kininy i kininovaya sistema krovi (biokhimiya, farmakologiya, patofiziologiya, metody issledovaniya, rol v patologii) [Kinins and kinin system of blood (biochemistry, pharmacology, pathophysiology, methods of assay, role in pathology)]. Moskow: Sbornik trudov 1 MMI imeni Sechenova 1976

    Google Scholar 

  • Paskhina, T.S.: Kallikrein plazmy krovi-novye funktsii (Plasma kallikrein: new functions). Review. Biokhimiia 41, 1347–1351 (1976)

    CAS  PubMed  Google Scholar 

  • Paskhina, T.S, Nartikova, V.F, Docenko, V.L, Maslova, T.M, Morozova, N.A, Trapeznikova, S.S, Yarovaya, L.M.: Sostoyanie kininovoy sistemy pri ojogovom shoke i ranney toksemii (State of kinin system in burn shock and early toxemia). Vopr. Med. Khim. 22, 696–707 (1976)

    CAS  PubMed  Google Scholar 

  • Paskhina, T.S, Makevnina, L. G, Egorova, T. P, Levina, G. O.: Identificatsiya kininov osvobozhdaemykh pankreaticheskim kallikreinom svinyi iz nizkomolekulyarnogo kininogena krolika (Identification of kinins released by pig pancreatic kallikrein from low molecular weight rabbit kininogen). Biokhimiia 42,1153–1155 (1977a)

    Google Scholar 

  • Paskhina, T.S, Polyanceva, L.R, Krinskaya, A.V, Belolipetskaya, Yu.G, Nartikova, V.F, Rossinskaya, E.B, Kargashin, LA.: Sostoyanie kininovoy sistemy i uroven ingibitorov proteinaz syvorotki krovi pri latentnom nefrite i nefroticheskom sindrome razlichnoy etiologii (State of kinin system and content of proteinase inhibitors in latent nephritis and nephrotic syndrome of various etiology). Vopr. Med. Khim. 23,241–251 (1977b)

    CAS  Google Scholar 

  • Paskhina, T.S, Dolgina, M.L, Nartikova, V.F, Krinskaya, A.V, Morozova, N.A, Rossinskaya, E. B.: Vliyanie polivalentnogo ingibitora proteinaz is lyogkikh byka na sostoyanie kininovoy sistemy pro ozhogovom shoke i ostroy ozhogovoy toksemii (The effect of polyvalent inhibitor of proteinase from bovine lung on the state of kinin in burn shock and acute burn toxemia). Vopr. Med. Khim. 23,689–700 (1977c)

    CAS  Google Scholar 

  • Pavlikhina, L.V, Eliseeva, Ju.E, Pozdnev, B.F, Orekhovich, V.N.: Opredelenie aktivnosti karboxikatepsina (peptidil-di-peptidasy) v syvorotke krovi cheloveka [Estimation of carboxycathepsin activity (peptidyl-dipeptidase) in human blood serum]. Vopr. Med. Khim. 21, 54–60 (1975)

    CAS  PubMed  Google Scholar 

  • Pogadaev, V.L, Timin, E.N.: Vlijanie biologicheski aktivnykh veshchestv (acetilkholina, histamina i bradikinina) na depolyarizovannuyu gladkuyu myshtsu taenia coli [Effects of biologically active agents (acetylcholine, histamine and bradykinin) on depolarized smooth muscle of taenia coli]. Biul. Eksp. Biol. Med. 81,12–14 (1976)

    CAS  PubMed  Google Scholar 

  • Polushkin, B.V, Kulaya, V.V, Latysheva, V.V, Ogorodova, T. S.: Bradikinin i ego rol v fiziologii i patologii koji (Bradykinin and its function in dermal physiology and pathology). Vestn. Dermatol. Venerol. No. 10,19–25 (1972)

    Google Scholar 

  • Popkova, G.A, Astapova, M.V, Lisunkin, Ju.J, Ravdel, G.A, Krit, N.A.: Sravnitelnoe izuchenie biologicheskoy aktivnosti i ustoychivosti k deystviyu tkanevykh kininaz analogov bradikinina, modificirovannykh v polojenii 8 (A comparative study of biological activity and resistance to tissue kininases of bradykinin analogs modified in position “8”). Bioorgan. Khim. 2,1606–1612 (1976)

    CAS  Google Scholar 

  • Popov, V.G, Melkumova, I.S, Sorokin, A.V.: Soderjanie kininogena v syvorotke krovi u bolnykh s koronarnoy nedostatochnostyu (The blood serum content of kininogen in patients with coronary insufficiency). Kardiologiia 11, No. 8,30–34 (1971)

    CAS  PubMed  Google Scholar 

  • Ravdel, G.A, Filatova, M.P, Shchukina, L.A, Paskhina, T.S, Surovicina, M.S., Trapeznikova, S.S, Egorova, T.P.: 6-Glycine-8-phenyllactic acid bradykinin. Its synthesis, biological activity, and splitting by kininase (carboxypeptidase N). J. Med. Chem. 10,242–246 (1967)

    CAS  PubMed  Google Scholar 

  • Ravdel, G.A, Monapova, N.N, Krit, N.A, Filatova, M.P, Lisunkin, Yu.L, Ivanov, V.T.: Sintez i biologicheskie svoystva bradikinin-potentsirujushchikh peptidov iz yada zmey (Synthesis and biological properties of bradykinin-potentiating peptides from snake venom). Khim. Prir. Soed (Uz. SSR) No. 1,47–56 (1975)

    Google Scholar 

  • Shchukina, L.A, Ravdel, G.A, Filatova, M.P, Syomkin, B.P, Krasnova, S.M.: Sintez bradikinina (Bradykinin synthesis). Khim. Prirodn. Soed. (Uz.SSR) No. 2, 124–130 (1966)

    CAS  Google Scholar 

  • Shevchenko, A. I.: K voprosu o deystvii bradikinina na gladkuyu muskulaturu bronkhov (On the action of bradykinin on smooth muscles of bronchi). In: Kinins and kinin system of blood. Sbornik nauchnykh Trudov 1 MMI im. Sechenova. Paskhina, T.S, Menshikov, V.V. (eds.), p. 48. Moscow: 1976 (Published by 1 MMI im. Sechenova)

    Google Scholar 

  • Shkhvatsabaya, I.K, Nekrasova, A.A.: Biologichesky aktivnye substancii-prostaglandiny i kininy, ikh rol v regulacii arterialnogo davleniya i razvitii arterialnoy hipertonii (Biologically active substances-prostaglandines and kinins and their function in regulation of arterial blood pressure and development of arterial hypertension). Kardiologiia 17, No. 2, 136–145 (1977)

    CAS  Google Scholar 

  • Shwartz, G.Ya, Liberman, S.S, Mashkovsky, M.D, Berlgand, E.A.: Eksperimentalnoe izuchenie protivovospalitelnogo deystviya piridinol-karbamata (Experimental investigation of antiphlogistic action of pyridinolcarbamate). Farmakol. Toksikol. 38,434–436 (1975)

    Google Scholar 

  • Shwartz, G.Ya, Mashkovsky, M.D.: (Vliyanie piridinolkarbamata (parmidina) na nekotorye effecty bradikinina [The influence of pyridinolcarbamate (parmidine) on some bradykinin effects]. Farmakol. Toksikol. 39,176–179 (1976)

    Google Scholar 

  • Stepanova, I.V, Vizir, A.D.: Kininovaya sistema krovi u bolnykh yazvennoy boleznyu (Kinine system of the blood in patients with ulcer disease). Vrach. Delo No. 10,21–22 (1974)

    Google Scholar 

  • Strigunov, V.I, Gaponyuk, P. Ya.: Primenenie bradikinina dlya differentsialnoy diagnostiki dobrokachestvennykh i zlokachestvennykh novoobrazovaniy (Application of bradykinin for differential diagnostics of benevolent and malignant formations). Med. Radiol. (Mosk.) 20, No. 8,11–13(1975)

    CAS  Google Scholar 

  • Stukalova, T.L, Lazareva, S.A, Ternovaya, L.A.: Aktivnost kallikrein-kininovoy sistemy pri eksperimentalnom infarkte miokarda u sobak i vliyanie na nee katekholaminov (Activity of kallikrein-kinin system in experimental myocardial infarction in dogs and effect on the system of exogenously administered catecholamines). Vopr. Med. Khim. 21, 88–91 (1975)

    CAS  PubMed  Google Scholar 

  • Surovikina, M.S.: Specificheskiy biologicheskiy metod opredeleniya svobodnykh kininov v venoznoy krovi cheloveka i jivotnykh (A specific biological method of determination free kinins in the venous blood of man and animals). Biul. Eksp. Biol. Med. 71, No. 5, 123–125 (1971)

    CAS  PubMed  Google Scholar 

  • Surovikina, M.S., Paleev, N.R, Gavrilova, R.D.: Kininy plazmy krovi i ikh znachenie v patologii organov dykhaniya (Kinins of blood plasma and their influence on the pathology of respiratory organs). Sov. Med. No. 12, 59–66 (1972)

    Google Scholar 

  • Surovikina, M. S.: Kininovaya sistema plazmy krovi pri eksperimentalnom allergicheskom miokardite (The kinin system of blood plasma in experimental allergic myocarditis). Kardiologiia 13, No. 2,119–123(1973)

    CAS  PubMed  Google Scholar 

  • Surovikina, M.S., Odinokova, V.A.: Patogeneticheskaya rol kininov pri allergicheskom povrejdenii miokarda (The pathogenetic role of kinins in allergic damage of the myocardium). Kardiologiia 14, No. 4,78–81 (1974)

    CAS  PubMed  Google Scholar 

  • Surovikina, M.S., Paleev, N.R, Gurevich, M.A, Dokukin, A.V, Yankovskaya, M.O.: Kininy plazmy i serdechno-sosudistaya sistema (Kinins of plasma and cardio-vascular system). Klin. Med. 52, No. 10,15–23 (1974)

    CAS  Google Scholar 

  • Surovikina, M. S.: Biologicheskiy metod opredelenia summarnoy aktivnosti kallikreina plasmy cheloveka i laboratornykh jyvotnykh (The biological method of determination total activity of human and of animals plasma kallikrein). Lab. Delo No. 1,6–9 (1975)

    Google Scholar 

  • Surovikina, M.S., Odinokova, V.A, Paleev, N.R, Gurevich, M.A, Yankovskaya, M.O.: Izmeneniya kompohentov kininovoy sistemy i struktury miokarda pod vliyaniem antikininovykh preparatov pri allergicheskom miokardite u krolikov (Changes in the components of the kinin system and in the myocardial structure under the effect of antikinin preparation in rabbits with allergic myocarditis). Biul. Eksp. Biol. Med. 81,979–981 (1976)

    Google Scholar 

  • Suvalskaya, L.A.: Kininogenazy i kininogen v plazme krovi bolnykh ostrym pankreatitom (Kininogenases and kininogen in the blood plasma of patients with acute pancreatitis). Klin. Med. 54, No. 2, 55–57 (1976)

    Google Scholar 

  • Trapesnikova, S.S, Mardashev, S.R.: Vydelenie, ochistka i svoystva ingibitora karboxipeptidazy N iz syvorotki krovi cheloveka (Isolation, purification, and properties of an inhibitor of carboxypeptidase N from human blood serum). Vopr. Med. Khim. 21,417–422 (1975)

    Google Scholar 

  • Trocka, V.: Summary of the literature published in Czechoslovakian, Polish, and Russian journals. In: Handbook of experimental pharmacology. Vol. XXV: Bradykinin, kallidin, and kallikrein. Erdös, E.G. (ed.), pp. 594–601. Berlin, Heidelberg, New York: Springer 1970

    Google Scholar 

  • Urzaeva, L.V, Dubley, P.V.: O nekotorykh aspektakh barriernoy functsii lyogkikh po otnosheniyu k ryadu vasoactivnykh veshchestv (On some aspects of barrier function of lung as regards some vasoactive substances). Usp. Sovrem. Biol. 83,139–153 (1977)

    Google Scholar 

  • Ushinsky, M.: Hipotenzionnye polipeptidy (kininy) v rodakh [Hypotensive polypeptides (kinines) in delivery]. Akush. Ginecol. No. 5,55–58 (1970)

    Google Scholar 

  • Veremeenko, K. N, Volokhonskaya, L. I, Kizim, A. I, Meged, N. F.: Opredelenie kallikreinogena i ingibitorov kallikreina v plazme krovi (Estimation of kallikreinogen and kallikrein inhibitors in blood plasma). Ukr. Biochim. Zh. 46,246–250 (1974)

    Google Scholar 

  • Veremeenko, K.N, Volokhonskaya, L.I, Kizim, A.L, Meged, N.F.: Metod opredeleniya kontaktnogo prekallikreina i inhibitorov kallikreina v plazme krovi cheloveka (A method for the determination of contact prekallikrein and inhibitors of kallikrein in human blood plasma). Lab. Delo No. 1,9–12 (1975)

    Google Scholar 

  • Veremeenko, K.N, Mitchenko, I.K, Gontar, A.M.: Izuchenie prekallikrein-kallikrein sistemy plazmy krovi pri virusnom gepatite (Studies of blood plasma prekallikrein-kallikrein system in virus hepatitis). Vrach. Delo No. 10,132–134 (1976a)

    Google Scholar 

  • Veremeenko, K.N, Verevka, V.S, Meged, N.F.: Issledovanie prekallikrein-kallikrein sistemy plazmy krovi pri ostrom pankreatite (Studies of blood plasma prekallikrein-kallikrein system in acute pancreatitis). Klin, Khir. No. 9, 5–9 (1976b)

    Google Scholar 

  • Veremeenko, K.N.: Kininovaya sistema (Kinin system). Kiev: Zdorovya 1977

    Google Scholar 

  • Virovets, S. I, Martynov, V. F, Titov, M. I.: Sintez argininosoderzhashchikh peptidov (Synthesis of arginine-containing peptides). Zh. Obshch. Khim. 38,2337 (1968)

    CAS  Google Scholar 

  • Vovchuk, S.V, Barabash, R.D, Levitsky, A.P.: Vydelenie i svoystva dvukh kallikreinov slyuny cheloveka (Purification and properties of two kallikreins of human saliva). Vopr. Med. Khim. 27,622–625 (1975)

    Google Scholar 

  • Vovchuk, S.V, Levitsky, A.P, Osadchy, B.D, Sokolov, S.A.: Vliyanie kallikreina podchelyustnykh jelez sobak na jeludochnuyu sekreciyu (The effects of kallikrein purified from dog submandibular salivary gland upon the gastric secretion). Fiziol. Zh. SSSR 63, 131–138 (1977)

    CAS  PubMed  Google Scholar 

  • Yarovaya, G.A.: Obshchye faktory regulatsii kininovoy sistemy, svertyvaniya krovi i fibrinoliza (General factors of regulation of kinin system, blood coagulation, and fibrinolysis). In: Khimicheskie faktory regulatsii aktivnosti i biosintesa fermentov (Chemical factors of regulation of activity and biosynthesis of enzymes). Orekhovich, V.N. (ed.), pp. 275–316. Moscow: Medicina 1969

    Google Scholar 

  • Zborovsky, A.B, Styajkova, R.A.: Aktivnost kininovoy sistemy krovi u bolnykh revmatizmom (The activity of kinin system in blood of patients with rheumatism). In: Kininy i kininovaya sistema krovi. Paskhina, T.C, Menshilov, V.V. (eds.), pp. 84–85. Sbornik Trudov 1 MMI imeni Sechenova. Moskva: 1976 (Published by 1 MMI im Sechenova)

    Google Scholar 

  • Zhukova, G.F, Ravdel, G.A, Shchukina, L.A, Paskhina, T.S, Gurtovenko, V.M.: Depsipeptidnye analogi eledoisina. Sintez i biologicheskaya aktivnost (Depsipeptide analogues of eledoisine. Synthesis and biological activity). Sovr. voprosy endokrinologii. Yudaev, N. A. (ed.), Vol. 4, pp. 99–107. Moskva: Medicina 1972

    Google Scholar 

  • Abe, K.: Urinary excretion of kinin in man with special reference to its origin. Tohoku J. Exp. Med. 87,175–179 (1965)

    CAS  PubMed  Google Scholar 

  • Cechova, A, Svestkova, V, Keil, B, Sorm, F.: Similarities in primary structures of cow colostrum trypsin inhibitor and bovine pancreatic trypsin inhibitor. FEBS Letters 4, 155–156 (1969)

    CAS  PubMed  Google Scholar 

  • Colman, R, Mason, I, Scherry, S.: The kallikreinogen-kallikrein enzyme system of human plasma. Assay of components and observations in disease states. Ann. Intern. Med. 71, 763–773 (1969)

    CAS  PubMed  Google Scholar 

  • Erdös, E, Yang, H.: An enzyme in microsomal fraction of kidney that inactivates bradykinin. Life Sci. 6,569–574 (1967)

    PubMed  Google Scholar 

  • Ferreira, S, Vane, J.: The detection and estimation of bradykinin in the circulating blood. Br. J. Pharmacol. 29,367–377 (1967)

    CAS  Google Scholar 

  • Fiedler, F.: Pig pancreatic kallikrein: structure and catalytic properties. Life Sci. 16, 788–789 (1975)

    Google Scholar 

  • Folk, J, Gladner, J.: Carboxypeptidase B. III. Specific esterase activity. Biochim. Biophys. Acta 33, 570–572 (1959)

    CAS  PubMed  Google Scholar 

  • Fujimoto, Y, Moriya, H, Moriwaki, C: Studies on human salivary kallikrein. J. Biochem. (Tokyo) 74,239–246(1973)

    CAS  Google Scholar 

  • Green, N, Work, E.: Pancreatic trypsin inhibitor. Biochem. J. 54,347–352 (1953)

    CAS  PubMed  Google Scholar 

  • Gregerman, R.: Identification of His-Leu and other histidyl peptides as normal constituents of human urine. Biochem. Med. 1,151–167 (1967)

    CAS  Google Scholar 

  • Griffin, J, Cochrane, C.: The mechanism for the involvement of HMW kininogen in surfacedependent reaction of Hageman factor (blood coagulation, factor XII, prekallikrein, factor XI, fibrinolisis). Proc. Natl. Acad. Sci. U.S.A. 73,2554–2558 (1976)

    CAS  PubMed  Google Scholar 

  • Habal, F.M, Movat, H.Z, Burrowes, C.E.: Isolation of two functionally different kininogens from human plasma. Separation from proteinase inhibitors and interaction with plasma kallikrein. Biochem. Pharmacol. 23,2291–2302 (1974)

    CAS  PubMed  Google Scholar 

  • Kato, H, Suzuki, T.: The location and nature of linkage of kinin moiety in bovine kininogen II. Biochem. Biophys. Res. Commun. 32,800–805 (1968)

    CAS  PubMed  Google Scholar 

  • Majno, G, Palade, G. E.: Studies of an inflammation. I. The effect of histamine and serotonin on vascular permeability. An electron microscopic study. J. Biophys. Biochem. Citol. 11, 571–606 (1961)

    CAS  Google Scholar 

  • Komiya, M, Kato, H, Suzuki, T.: Bovine plasma kininogens. III. Structure comparison of HMW and LMW-kinonogens. J. Biochem. (Tokyo) 76,833–845 (1974)

    CAS  Google Scholar 

  • Moriya, H, Moriwaki, Ch, Yamazaki, K, Akimoto, S, Fukushima, H.: Human salivary kallikrein and liberation of colostrokinin. In: Hypotensive peptides. Erdös, E.G., Back, N, Sicuteri, F. (eds.), pp. 161–174. Berlin, Heidelberg, New York: Springer 1966

    Google Scholar 

  • Movat, H, Habal, F, McMorine, D.: Neutral proteases of human PMN leukocytes with kininogenase activity. Int. Arch. Allergy Appl. Immunol. 50,257–281 (1976)

    CAS  PubMed  Google Scholar 

  • Piquilloud, Y, Reinharz, A, Roth, M.: Studies on the angiotension converting enzyme with different substrates. Biochim. Biophys. Acta 206,136–142 (1970)

    CAS  PubMed  Google Scholar 

  • Schench, F, Oberdorf, A, Schmidt-Kastner, G.: Verfahren zur Herstellung eines Bradykinin homologen Nonapeptides. Ger. Pat. 1, 298, 997 (1969)

    Google Scholar 

  • Skeggs, L, March, W, Kahn, J, Shumway, N.: Existence of two forms of hypertensin. J. Exp. Med. 99,275–282(1954)

    CAS  PubMed  Google Scholar 

  • Trautschold, I, Werle, E.: Spectrophotometrische Bestimmung des Kallikrein und seiner Inaktivatoren. Hoppe Seylers Z. Physiol. Chem. 325,48–59 (1961)

    CAS  PubMed  Google Scholar 

  • Vane, J.: The release and fate of vaso-active hormones in the circulation. Br. J. Pharmacol. 35, 209–215 (1969)

    CAS  PubMed  Google Scholar 

  • Wolf, E, Schirmer, E, Folk, J.: The kinetics of carboxypeptidase B activity. I. Kinetic parameters. J. Biol. Chem. 237, 3094–3099 (1962)

    Google Scholar 

  • Yang, H, Erdös, E.: Second kininase in human blood plasma. Nature (Lond.) 215, 1402–1403 (1967)

    CAS  Google Scholar 

  • Zweifach, B.W.: Ismeneniya sostoyanya krowenostnich kapillyarov i ich pronitsaemosti (Changes in blood capillary behavior and their permeability). Patol. Fiziol. Eksp. Ter. No. 2, 6–16 (1964)

    Google Scholar 

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Authors
  1. T. S. Paskhina
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  2. A. P. Levitsky
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  1. Departments of Pharmacology, and Internal Medicine, The University of Texas, Southwestern Medical School, 5323 Harry Hines Blvd., Dallas, TX, 75235, USA

    Ervin G. Erdös

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Paskhina, T.S., Levitsky, A.P. (1979). Bradykinin, Kallidin, and Kallikreins. In: Erdös, E.G. (eds) Bradykinin, Kallidin and Kallikrein. Handbook of Experimental Pharmacology, vol 25 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67301-6_17

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