Abstract
From all the antigens which have been found in human tumors in the last 13 years and which are grouped under the common denominator of carcinofetal antigens (CFA) only a few have been sufficiently characterized as to allow clinical trial and application, and even less have reached medical interest. In fact, there are only two which are important, namely, the AFP and the CEA, and therefore they shall be discussed here in greater detail.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
ABELEV, G.I., PEROVA, S.D., KRAMKOVA, Z.A., et al.: Transplantation 1, 174 (1963)
BUFFE, D., RIMBAUT, C.: Biomedicine 19, 172 (1973)
BURTIN, P., MARTIN, E., SABINE, M.C., KLEIST von, S.: J. Natl. Cancer Inst. 48, 25 (1972)
CHU, T.M.: Comm. 5th Meeting of the Int. Study Group of Carcinoembryonic Proteins. Copenhagen, 6–9 Aug. (1977)
COLLATZ, E., KLEIST von, S., BURTIN, P.: Int. J. Cancer 8, 298 (1971)
DARCY, D.A., TURBERVILLE, C., JAMES, R.: Br. J. Cancer 28, 147 (1973)
DENK, H., TAPPEINER, G., ECKERSTORFER, R., HOLZNER, J.H.: Int. J. Cancer 10, 262 (1972)
GOLD, Ph.: Cancer 20, 1663 (1967)
GOLD, Ph., FREEDMAN, S.O.: J. Exp. Med. 12, 439 (1965)
GOLD, Ph., KRUPEY, J., ANSARI, H.: J. Natl. Cancer Inst. 45, 219 (1970)
GOLDENBERG, D.: Curr. Top. Pathol. 63., 289 (1976)
HIRAI, H., NISHI, S., WATABE, H., et al.: Garni Monogr. Cancer Res. 14 13 (1973)
HOLLINSHEAD, A., Mc WRIGHT, C.S., ALFORT, T.C., et al.: Science 177, 887 (1972)
KLEIST von, S.: Z. Krebsforsch. 90, 1 (1977)
KLEIST von, S., BURTIN, P.: Int. J. Cancer 4, 874 (1969)
KLEIST von, S., CHAVANEL, G., BURTIN, P.: Proc. Natl. Acad. Sci. USA 69, 2492 (1972)
KLEIST von, S., TROUPEL, S., BURTIN, P.: Br. J. Cancer 35, 875 (1977)
LEJTENYI, M.C., FREEDMAN, S.O., GOLD, Ph.: Cancer 28, 115 (1971)
LO GERFO, P., KRUPEY, J., HANSEN, H.J.:N. Engl. J. Med. 285, 138 (1971)
LO GERFO, P., HERTER, F.P., BENNETT, S.J.: Int. J. Cancer 9, 344 (1972)
MACH, J.P., PUSZTASZERI, G.: Immunochemistry 9, 1031 (1972)
MACH, J.P., PUSZTASZERI, G., MAC DONALD, D., BERTHOLET, M.: Johns Hopkins Med. J. Suppl. 3, 369 (1974)
MARTIN, E.W., KIBBEY, W., DI VECCHIA, L., et al.: Cancer 37, 62 (1976)
MARTIN, E.W., JAMES, K., HURTUBISE, P.E., et al.: Cancer 39, 440 (1977)
NEVILLE, M.A., LAURENCE, D.J.R.: Int. J. Cancer 14, 1 (1974)
NEWMAN, E.S., PATRAS, S.E., GEORGIADIS, A., et al.: Cancer Res. 34, 2125 (1974)
ØRJASAETER, H.: Acta Pathol. Microbiol. Scand. Sect. B. 82, (1974)
SEPPÄLA, M., RUOSLAHTI, E.: Lancet I, 375 (1972)
STAAB, H.J., ANDERER, F.A., STUMPF, E., FISCHER, R.: Dtsch, Med. Wochenschr. 102, 1082 (1977)
TATARINOV, Yu. S., AFANASYEVA, A.C.: Bull. Exp. Biol. Med. 59, (1965)
TERRY, W.D., HENKART, P.A., COLLIGAN, J.A., TODD, C.W.: J. Exp. Med. 136, 200 (1972)
THOMSON, D.M.P., KRUPEY, J., FREEDMAN, S.O., GOLD, Ph.: P.N.A.S. (U.S.A.) 64, 161 (1969)
TURBERVILLE, C., DARCAY, D.A., LAURENCE, D.J., et al.: Immunochemistry 10, 841 (1973)
WANG, D.Y., BULBROOK, R.D., HAYWARD, J.L. et al.: Europ. J. Cancer 11, 615 (1975)
ZAMCHECK, N., MOORE, T.L., DHAR, P., KUPCHICK, H.Z., SOROKIN, J.: Natl. Cancer Inst. Monogr. 35, 433 (1972)
ZAMCHECK, N., MOORE, T.L., DHAR, P. et al.:N. Engl. J. Med. 286, 83 (1972)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1979 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
von Kleist, S. (1979). Clinical Significance of Carcinofetal Antigens with Special Reference to CEA, AFP, and Related Substances. In: Flad, HD., Herfarth, C., Betzler, M. (eds) Immunodiagnosis and Immunotherapy of Malignant Tumors. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67166-1_5
Download citation
DOI: https://doi.org/10.1007/978-3-642-67166-1_5
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-09161-5
Online ISBN: 978-3-642-67166-1
eBook Packages: Springer Book Archive