Discussion

  • M. Micksche
  • C. Cerni
  • P. Fischer
  • M. Vetterlein
Conference paper

Abstract

During the ensuing discussion M. MICKSCHE, C. CERNI, P. FISCHER, and M. VETTERLEIN reported on “tumor-associated antigens on somatic cell hybrids derived from human lung cancer cells.” In 1971 a squamous cell carcinoma of the lung was established as a continuously growing cell line in culture (E-14 line). Somatic cell hybrids were produced between the E-14 line and a hamster fibroblast cell line. A karyotype analysis revealed the presence of human chromosomes in the cell hybrids designated M10 and M29. Expression of tumor-associated antigens on hybrid cells and E-14 cells was demonstrated by means of an antiserum against E-14 cells produced in rabbits and tested by indirect immunofluorescence.

Keywords

Migration 

References

  1. 1.
    HOLLINSHEAD, A.C., STEWART, T.H.M., HERBERMAN, R.B.: J. Natl. Cancer Inst. 52, 327–338 (1974)PubMedGoogle Scholar
  2. 2.
    MICKSCHE, M., CERNI, C., KOKOSCHKA, E.M., WRBA, H.: Biological characterization of human tumours. Exc. Med. 375, 337–345 (1975)Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1979

Authors and Affiliations

  • M. Micksche
  • C. Cerni
  • P. Fischer
  • M. Vetterlein

There are no affiliations available

Personalised recommendations