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Discussion

  • M. Micksche
  • C. Cerni
  • P. Fischer
  • M. Vetterlein
Conference paper

Abstract

During the ensuing discussion M. MICKSCHE, C. CERNI, P. FISCHER, and M. VETTERLEIN reported on “tumor-associated antigens on somatic cell hybrids derived from human lung cancer cells.” In 1971 a squamous cell carcinoma of the lung was established as a continuously growing cell line in culture (E-14 line). Somatic cell hybrids were produced between the E-14 line and a hamster fibroblast cell line. A karyotype analysis revealed the presence of human chromosomes in the cell hybrids designated M10 and M29. Expression of tumor-associated antigens on hybrid cells and E-14 cells was demonstrated by means of an antiserum against E-14 cells produced in rabbits and tested by indirect immunofluorescence.

Keywords

Squamous Cell Carcinoma Cell Hybrid Human Lung Cancer Cell Somatic Cell Hybrid Migration Inhibition 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    HOLLINSHEAD, A.C., STEWART, T.H.M., HERBERMAN, R.B.: J. Natl. Cancer Inst. 52, 327–338 (1974)PubMedGoogle Scholar
  2. 2.
    MICKSCHE, M., CERNI, C., KOKOSCHKA, E.M., WRBA, H.: Biological characterization of human tumours. Exc. Med. 375, 337–345 (1975)Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1979

Authors and Affiliations

  • M. Micksche
  • C. Cerni
  • P. Fischer
  • M. Vetterlein

There are no affiliations available

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