Abstract
The experimental basis for this trial was discussed by Fanny Lacour, in this volume (Chapter 9). Poly A:poly U, when given after surgery, was found to have a definite inhibitory effect on tumor growth, at least in the case of spontaneous mammary adenocarcinoma in mice and transplantable melanoma in hamsters. As used, this complex had neither toxic nor enhancing effects. Moreover, when poly A:poly U was administered to newborn C3H/He mice, it had a prophylactic effect, and the tumor incidence was significantly lower in the treated group than among the controls.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Bloom, H. J. G. and Richardson, W. W. Histological grading and prognoses in breast cancer. British J. Cancer, 11:359, 1957.
Segal, A., Weiler, D., Genin, J., Lacour, J., and Lacour, F. In vitro study of cellular immunity against autochtonous human cancer. Int. J. Cancer, 2:417, 1972.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1975 Springer-Verlag New York Inc.
About this chapter
Cite this chapter
Lacour, J. (1975). Trials with Poly A:Poly U as Adjuvant Therapy Complementing Surgery in Randomized Patients with Breast Cancer. In: Gottlieb, A.A., Plescia, O.J., Bishop, D.H.L. (eds) Fundamental Aspects of Neoplasia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66112-9_16
Download citation
DOI: https://doi.org/10.1007/978-3-642-66112-9_16
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-66114-3
Online ISBN: 978-3-642-66112-9
eBook Packages: Springer Book Archive