Buccal Absorption of Drugs

  • Arnold H. Beckett
  • R. D. Hossie
Part of the Handbuch der experimentellen Pharmakologie/Handbook of Experimental Pharmacology book series (HEP, volume 28 / 1)

Abstract

The buccal cavity is lined with a mucous membrane which, like the lining of the entire alimentary canal, behaves as a lipoidal barrier to the passage of drugs (Schanker, 1962). In general, drugs penetrate the mucous membrane by simple diffusion and are carried in the blood that richly supplies the salivary glands and their ducts into the general circulation via the jugular vein. Active transport, pinocytosis, and passage through aqueous pores usually play only insignificant roles in moving drugs across the oral mucosa.

Keywords

Testosterone Imipramine Barbiturate Ephedrine Antipyrine 

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Copyright information

© Springer-Verlag Berlin · Heidelberg 1971

Authors and Affiliations

  • Arnold H. Beckett
  • R. D. Hossie

There are no affiliations available

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