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Buccal Absorption of Drugs

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Concepts in Biochemical Pharmacology

Abstract

The buccal cavity is lined with a mucous membrane which, like the lining of the entire alimentary canal, behaves as a lipoidal barrier to the passage of drugs (Schanker, 1962). In general, drugs penetrate the mucous membrane by simple diffusion and are carried in the blood that richly supplies the salivary glands and their ducts into the general circulation via the jugular vein. Active transport, pinocytosis, and passage through aqueous pores usually play only insignificant roles in moving drugs across the oral mucosa.

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Authors
  1. Arnold H. Beckett
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  2. R. D. Hossie
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Editor information

Editors and Affiliations

  1. Department of Health, Education and Welfare, National Institutes of Health, 20014, Bethesda, MD, USA

    Bernard B. Brodie  & James R. Gillette  & 

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Beckett, A.H., Hossie, R.D. (1971). Buccal Absorption of Drugs. In: Brodie, B.B., Gillette, J.R., Ackerman, H.S. (eds) Concepts in Biochemical Pharmacology. Handbuch der experimentellen Pharmakologie/Handbook of Experimental Pharmacology, vol 28 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-65052-9_3

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  • DOI: https://doi.org/10.1007/978-3-642-65052-9_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-65054-3

  • Online ISBN: 978-3-642-65052-9

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