Concepts in Biochemical Pharmacology

Part 1

  • Bernard B. Brodie
  • James R. Gillette
  • Helen S. Ackerman

Table of contents

  1. Front Matter
    Pages I-XVI
  2. Routes of Drug Administration

    1. C. Adrian M. Hogben
      Pages 1-8
    2. Arnold H. Beckett, R. D. Hossie
      Pages 25-46
    3. L. T. Greene
      Pages 88-102
    4. Martin Katz, Boyd J. Poulsen
      Pages 103-174
  3. Sites of Drug Transport and Disposition

  4. Sites of Drug Excretion

    1. I. M. Weiner
      Pages 328-353
    2. R. L. Smith
      Pages 354-389

About this book

Introduction

This volume of the Handbook of Experimental Pharmacology (Concepts in Biochemical Pharmacology) will show that pharma­ cology has finally arrived as a true discipline in its own right, and is no longer the handmaiden of organic chemistry and physiology. Instead it is an amalgam of all the biological sciences including biochemistry, biophysical chemistry, physiology, pathology and clinical medicine. In the volumes that make up Concepts in Bioche­ mical Pharmacology we hope to convince Medical Schools what should now be obvious, that pharmacology is no longer that dull topic bridging the basic sciences with medicine, but is probably the most important subject in the medical curriculum. We are grateful for the advice of Dr. BYRON CLARKE, Director of the Pharmacology-Toxicology Program at the National Insti­ tutes of Health, whose support made possible much of the work described in this volume. Contents Section One: Routes of Drug Administration Chapter 1: Biological Membranes and Their Passage by Drugs. C. A. M. HOGBEN 1 References. . . . . . . . . . . . . . . . . . . . . . . . . . 8 Chapter 2: Absorption of Drugs from the Gastrointestinal Tract. L. S. SCHANKER. With 5 Figures. 9 I. Introduction. . . . . . . . . . . . . . . . . . . . . . . 9 II. Methods of Study. . . . . . . . . . . . . . . . . . . . . 9 III. Absorption from the Stomach . . . . . . . . . . . . . . . 11 IV. Intestinal Absorption of Non-Electrolytes and Weak Electrolytes 15 V. Absorption of Weak Electrolytes from the Colon and Rectum 18 VI. Intestinal Absorption of Organic Ions. . . . . . . . . . 19 VII. Intestinal Absorption of Macromolecules . . . . . . . . . . 19 VIII. Active Transport across the Intestinal Epithelium . . . . . 20 IX. Effect of EDTA on Drug Absorption from the Intestine . . . . . . .

Keywords

Biochemie Gesundheitsberichterstattung Pharmakologie absorption biochemistry chemistry drug medicine organic chemistry pathology pharmacology physiology toxicology

Editors and affiliations

  • Bernard B. Brodie
    • 1
  • James R. Gillette
    • 1
  • Helen S. Ackerman
  1. 1.Department of Health, Education and WelfareNational Institutes of HealthBethesdaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-65052-9
  • Copyright Information Springer-Verlag Berlin Heidelberg 1971
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-65054-3
  • Online ISBN 978-3-642-65052-9
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • About this book
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