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Urogenital Ageing and Dermatology

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Estrogens and Antiestrogens II

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 135 / 2))

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Abstract

The cessation of ovarian function after menopause is associated with a variety of symptoms from the urogenital tract in many postmenopausal women such as urinary incontinence, urgency, recurrent urinary tract infection, and dyspareunia (OLDENHAVE et al. 1993). The underlying condition is the development of local atrophy of the urethral and vaginal epithelium and their supportive tissues. The gradual increase of these symptoms is age-dependent. Thus, a substantial number of women at very old age are affected. One specific feature attached to this complex set of symptoms frequently referred to as urogenital aging is the influence of personal attitudes and cultural background towards hygiene and sexuality by both menopausal women and health care providers.

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References

  • Barentsen R, van der Weijer PHM, Schram JHN (1997) Continuous low dose estradiol released from a vaginal ring versus estriol vaginal cream for urogenital atrophy, Eur J Obstet Gynecol 71:73–80

    Article  CAS  Google Scholar 

  • Barlow DH, Samsioe G, van Geelen JM (1997) A study of European women’s experience of the problems of urogenital aging and its management. Maturitas 27:239–247

    Article  PubMed  CAS  Google Scholar 

  • Bolognia JL, Bravermann 1M, Rousseau ME, Sarrel PM (1989) Skin changes in menopause. Maturitas 11:295–304

    Google Scholar 

  • Brincat M, Studd JWW, Moniz CF, Parson V, Darby AJ (1984) Skin thickness measurement. A simple screening method for determining patients at risk ofdeveloping postmenopausal osteoporosis. In: Christiansen C, Arnaud CD, Nordin BEC, Parfitt AM, Peck WA, Riggs BL (eds) Osteoporosis, Proceedings of the Copenhagen international symposium on osteoporosis. Aalborg Styftsbogtrykkeri, Aalborg, pp 323–326

    Google Scholar 

  • Brincat M, Kabalan S, Studd JWW, Moniz CF, de Trafford J, Montgomery J (1987a) A study of the decrease of skin collagen content, skin thickness, and bone mass in the postmenopausal woman. Obstet Gynecol 70:840–845

    PubMed  CAS  Google Scholar 

  • Brincat M, Moniz CF, Kabalan S, Versi E, OTiowd T, Magos AL, Montgomery J, Studd JWW (1987b) Decline in skin collagen content and metacarpal index after the menopause and its prevention with sex hormone replacement. Br J Obstet Gynaecol 94:126–129

    CAS  Google Scholar 

  • Brincat M, Versi E, Moniz CF, Magos A, de Trafford J, Studd JWW (1987c) Skin collagen changes in postmenopausal women receiving different regimens of estrogen therapy. Obstet Gynecol 70:123–127

    PubMed  CAS  Google Scholar 

  • Burgio KL, Matthews KA, Engle BT (1991) Prevalence, incidence and correlates of urinary incontinence in healthy, middle aged women. J Urol 146:1255–1259

    PubMed  CAS  Google Scholar 

  • Bygdeman M, Swahn ML (1996) Replens versus dienoestrol cream in the symptomatic treatment of vaginal atrophy in postmenopausal women. Maturitas 23:259–263

    Article  PubMed  CAS  Google Scholar 

  • Cheang A, Sitruk-Ware R, Utian W (1993) A risk-benefit appraisal of transdermal estradiol. Drug Safety 9:365–379

    Article  PubMed  CAS  Google Scholar 

  • Dunn LB, Damesyn M, Moore AA, Reuben DB, Greendale GA (1997) Does estrogen prevent skin aging? Results from the First National Health and Nutrition Examination Survey (NHANES 1) Arch Dermatol 133:339–342

    Article  Google Scholar 

  • Fantl JY, Cardozo L, McClish DK, and The Hormones and Urogenital Therapy Committee (1994) Estrogen therapy in the management of urinary incontinence in postmenopausal women: a meta-analysis. First report of the hormones and urogenital therapy committee. Obstet Gynecol 83:12–8

    PubMed  CAS  Google Scholar 

  • Haapasaari K-M, Raudaskoski T, Kallionen M, Suvanto-Luukkonen E, Kauppila A, Lalira E, Risteli J, Oikarinen A (1997) Systemic therapy with estrogen or estrogen with progestin has no effect on skin collagen in postmenopausal women. Maturitas 27:153–162

    Article  PubMed  CAS  Google Scholar 

  • Holland EF, Studd JWW, Mansell JP, Leather AT, Bailey AJ (1994) Changes in collagen composition and cross-links in bone and skin osteoporotic postmenopausal women treated with percutaneous estradiol implants. Obstet Gynecol 83: 180-183

    PubMed  CAS  Google Scholar 

  • Iosif CS, Batra S, Ek A, Ã…stedt B (1981) Estrogen receptors in the human female lower urinary tract. Am J Obstet Gynecol 141:817–820

    PubMed  CAS  Google Scholar 

  • Iosif C, Bekassy Z (1984) Prevalence of genito-urinary symptoms in the late menopause. Acta Obstet Gynecol Scand 63:257–260

    Article  PubMed  CAS  Google Scholar 

  • Kenemans P, Barentsen R, van der Weijer P (1996) Other climacteric complaints and symptoms. In: Kenemans P, Barentsen R, van der Weijer P (eds) Practical HRT, 2nd edn. Medical Forum International, Zeist, The Netherlands, p 53

    Google Scholar 

  • Maheux R, Naud F, Rioux M, Grenier R, Lemay A, Guy J, Langevin M (1994) A randomized, double-blind, placebo-controlled study on the effect of conjugated estrogens on skin thickness. Am J Obstet Gynecol 170:642–649

    PubMed  CAS  Google Scholar 

  • Maheux R, Guy J, Dumont M, Maesse B (1996) Correlation between skin thickness and bone mass in women. Menopause 3:197–200

    Article  Google Scholar 

  • McConkey B, Fraser GM, Bligh AS, Whitely H(1963) Transparent skin and osteoporosis. Lancet 1:693–695

    Article  Google Scholar 

  • Meschia M, Bruschi F, Amicarelli F, Barbacini P, Monza GC, Crosignani PG (1994) Transdermal hormone replacement therapy and skin in post-menopausal women: a placebo controlled study. Menopause 1:79–82

    Article  Google Scholar 

  • Molander U, Milsom I, Ekelund P, Mellstrom D (1990) An epidemiological study of urinary incontinence and related urogenital symptoms in elderly women. Maturitas 12:51–60

    Article  PubMed  CAS  Google Scholar 

  • Nelson DA, Kleerekoper M, Peterson E, Parfitt AM (1993) Skin color and body size as risk factors for osteoporosis. Osteoporosis Int 3:18–23

    Article  Google Scholar 

  • Oldenhave A, Jaszman UB, Haspels AA, Everaerd WTAM(1993) Impact of climacteric on well-being: a survey based on 5213 women aged 39 to 60 years old. Am J Obstet Gynecol 168:772–780

    PubMed  CAS  Google Scholar 

  • Pierard GE, Letawe C, Dowlati A, Pierard-Franchimont C (1995) Effect of hormone replacement therapy for menopause on the mechanical properties of skin. J Am Geriatr Soc 43:662–665

    PubMed  CAS  Google Scholar 

  • Pierard-Franchimont C, Letawe C, Goffin V, Pierard GE (1995) Skin water-holding capacity and transdermal estrogen therapy for menopause: a pilot study. Maturitas 22:155–161

    Article  Google Scholar 

  • Punnonen R (1972) Effect of castration and peroral estrogen therapy on the skin. Acta Obstet Gynecol Scand 21:S3–S44

    Google Scholar 

  • Punnonen R, Vilska S, Rauramo L (1984) Skinfold thickness and long-term postmenopausal hormone therapy. Maturitas 5:259–262 ..

    Article  PubMed  CAS  Google Scholar 

  • Rauramo Land Punnonen R (1969) Wirkung einer oralen Therapie mit Ostriolsuccinat auf die Haut kastrierter Frauen. Z Haut Geschl Kr 44:463–470

    CAS  Google Scholar 

  • Rud T (1980) Urethral pressure profile in continent women from childhood to old age. Acta Obstet Gynecol Scand 59:331–335

    Article  PubMed  CAS  Google Scholar 

  • Samsioe G, Jansson I, Mellstrom D, Svanborg A (1985) Occurence, nature and treatment of urinary incontinence in a 70-year-old female population. Maturitas 7:335–342

    Article  PubMed  CAS  Google Scholar 

  • Sarrel PM (1990) Sexuality and menopause. Obstet Gynecol 75:26S–32S

    PubMed  CAS  Google Scholar 

  • Savvas M, Bishop J, Laurent G, Watson N, Studd J (1993) Type III collagen content in the skin of postmenopausal women receiving oestradiol and testosterone implants. Br J Obstet Gynaecol 100:154–156

    Article  PubMed  CAS  Google Scholar 

  • Schmidt JB, Binder M, Macheiner W, Kainz Ch, Gitsch G, Bieglmayer Ch (1994) Treatment of skin ageing symptoms in perimenopausal females with estrogen compounds. A pilot study. Maturitas 20:25–30

    CAS  Google Scholar 

  • Shelley WB, Shelley ED, Talanin NY, Santoso-Pham J, Toledo DO (1995) Estrogen dermatitis. J Am Acad Dermatol 32:25–31

    Article  CAS  Google Scholar 

  • Smeets AJ, Kujper JW, van Kuijk C, Berning B, Zwamborn AW (1994) Skin thickness does not reflect bone mineral density in postmenopausal women. Osteoporosis Int 4:32–35

    Article  Google Scholar 

  • Sultana CJ, Walters MD (1994) Estrogen and urinary incontinence. Maturitas 20: 129–138

    Article  PubMed  CAS  Google Scholar 

  • Sutherst JR (1979) Sexual dysfunction and urinary incontinence. Br J Obstet Gynecol 86:387–388

    Article  CAS  Google Scholar 

  • Tan CY, Statham B, Marks R, Payne PA (1982) Skin thickness measurement by pulsed ultrasound: its reproducibility, validation and variability. Br J Dermatol 106: 657–667

    PubMed  CAS  Google Scholar 

  • van Geelen JM, van der Weijer PHM, Arnolds HT (1996) Urogenital verschijnselen en hinder daarvan bij thuiswonende Nederlandse vrouwen van 50-75 jaar (Urogenital symptoms and resulting discomfort in non-institutionalized Dutch women aged 50 to 75 years). Ned Tijdschr Genesk 140:713–716

    Google Scholar 

  • Varila E, Rantala I, Oikarinen A, Risteli J, Reunala T, Oksanen H, Punnonen R (1995) The effect of topical oestriol on skin collagen of postmenopausal women. Br J Obstet Gynaecol 102:985–989

    Article  PubMed  CAS  Google Scholar 

  • Walter S, Wolf H, Barlebo H, Jensen HK (1978) Urinary incontinence in postmenopausal women treated with estrogens: A double-blind clinical trial. Urol Int 33:135–143

    Article  Google Scholar 

  • Wilson PD, Faragher B, Butler B, Bu’Lock D, Robinson EL, Brown ADG (1987) Treatment with oral piperazine oestrone sulphate for genuine stress incontinence in postmenopausal women. Br J Obstet Gynecol 94:568–574

    Article  CAS  Google Scholar 

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Authors
  1. M. Dören
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© 1999 Springer-Verlag Berlin Heidelberg

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Dören, M. (1999). Urogenital Ageing and Dermatology. In: Estrogens and Antiestrogens II. Handbook of Experimental Pharmacology, vol 135 / 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60107-1_23

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  • DOI: https://doi.org/10.1007/978-3-642-60107-1_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64261-6

  • Online ISBN: 978-3-642-60107-1

  • eBook Packages: Springer Book Archive

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