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Immundefizienz als Ursache für die Entstehung hämatologischer Neoplasien

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Molekularmedizinische Grundlagen von hämatologischen Neoplasien

Part of the book series: Molekulare Medizin ((MOLMED))

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Zusammenfassung

Zwischen Viren und dem humanen Immunsystem besteht eine enge Abhängigkeit. Die Entwicklung beider Partner im Lauf der Evolution hat zu spezifischen Anpassungen des einen an den anderen geführt. Zum Beispiel weisen molekularbiologische Argumente darauf hin, dass Retroviren einen wichtigen Faktor in der Evolution des humanen Immunsystems darstellen (Bagasra u. Amjad 2000, Villareal 1997). Es ist somit nicht erstaunlich, dass virale Infektionen und Alterationen des Immunsystems für hämatologische Neoplasien prädisponieren, die selbst oft Erkrankungen des Immunsystems darstellen.

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  1. Bettina Borisch
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  2. Paulette Mhawech
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  3. Marianne Tinguely
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  1. Max-Delbrück-Centrum für Molekulare Medizin, Robert-Rössle-Str. 10, 13122, Berlin-Buch, Deutschland

    Detlev Ganten  & Klaus Ruckpaul  & 

  2. Intitut für Zell- und Molekularpathologie, Medizinische Hochschule Hannover, Carl-Neuberg-Straße 1, 30623, Hannover, Deutschland

    Brigitte Schlegelberger

  3. Medizinische Fakultät, Institut für Medizinische Biologie, Universität Wien, Währinger Gürtel 10, A-1090, Wien IX, Österreich

    Christa Fonatsch

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Borisch, B., Mhawech, P., Tinguely, M. (2003). Immundefizienz als Ursache für die Entstehung hämatologischer Neoplasien. In: Ganten, D., Ruckpaul, K., Schlegelberger, B., Fonatsch, C. (eds) Molekularmedizinische Grundlagen von hämatologischen Neoplasien. Molekulare Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59343-7_6

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