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Hochmaligne B-Zell-Lymphome

  • Brigitte Schlegelberger
  • Martin Lipp
Part of the Molekulare Medizin book series (MOLMED)

Zusammenfassung

Erst in diesem Jahr ist durch die WHO-Klassifikation eine weltweit akzeptierte Basis für die histopathologische Beurteilung der malignen Lymphome geschaffen worden. Über Jahrzehnte hinweg waren die wissenschaftliche Diskussion und die Interpretation klinischer Daten insbesondere zu hochmalignen B-Zell-Lymphomen durch die unterschiedlichen Klassifikationssysteme erschwert: In den USA wurde überwiegend die so genannte Working Formulation benutzt, die ursprünglich nicht als eigenständiges Klassifikationssystem, sondern als „Übersetzungshilfe“für verschiedene, nicht vereinbare Klassifikationssysteme zum Vergleich klinischer Studien konzipiert war. In Europa fand dagegen die 1974 vorgestellte und 1988 überarbeitete Kiel-Klassifikation Anwendung, die auf dem Prinzip beruht, die Non-Hodgkin-Lymphome auf der Basis des zytologischen Erscheinungsbilds einzuteilen (Stansfeld et al. 1988; Lennert u. Feller 1992).

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© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • Brigitte Schlegelberger
  • Martin Lipp

There are no affiliations available

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