Skip to main content

Induktionschemotherapie bei Tumoren des Beckens – das Zervixkarzinom

  • Chapter
Regionale Therapie maligner Tumoren
  • 1140 Accesses

Zusammenfassung

Nach dem Mammakarzinom ist das Zervixkarzinom weltweit die zweithäufigste, tumorbedingte Todesursache bei Frauen. In der westlichen Welt sterben jährlich etwa 40.000 Frauen am fortgeschrittenen Zervixkarzinom; in Entwicklungsländern sind es sechsmal so viele. Diese schlechte Prognose bei einer grundsätzlich vermeidbaren Krebserkrankung kann durch die Frühdiagnose mittels Papanicolaou-Screening entscheidend verbessert werden.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 139.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 159.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Rose PG, Bundy BN, Watkins EB, et al: Concurrent cisplatin- based radiotherapy and chemotherapy for locally advanced cervical cancer. N Engl J Med 340: 1144–1153, 1999.

    Article  PubMed  CAS  Google Scholar 

  2. Peters WA III, Liu PY, Barret RJ Jr, et al: Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after redical surgery in high-risk early-stage cancer of the cervix. J Clin Oncol 18: 1606–1613, 2000.

    PubMed  CAS  Google Scholar 

  3. Keys HM, Bundy BN, Stehman FB, et al: Cisplatin, radiation and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma. N Engl J Med 340:1154–1161, 1999.

    Article  PubMed  CAS  Google Scholar 

  4. Morris M, Eifel PJ, Lu J, et al: Pelvic irradiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer: N Engl J Med 340:1137–1143, 1999.

    Article  PubMed  CAS  Google Scholar 

  5. Eifel PJ, Winter K, Morris M, et al: Pelvic irradiation with concurrent chemotherapy versus pelvic and para-aortic irradiation for high-risk cervical cancer: An update of Radiation Therapy Oncology Group trial (RTOG) 90-01. J Clin Oncol 22:872–880, 2004.

    Article  PubMed  Google Scholar 

  6. Yessaian A, Magistris A, Burger RA, et al: Radical hysterectomy followed by tailored postoperative therapy in the treatment of stage IB2 cervical cancer: Feasibility and indications for adjuvant therapy. Gynecol Oncol 94:61–66, 2004.

    Article  PubMed  Google Scholar 

  7. Bradley JM, Krishnansu ST, Wui-Jin K, et al: Multimodality therapy for locally advanced cervical carcinoma: State of the art and future directions. J Clin Oncol 25:2952–2965, 2007.

    Article  Google Scholar 

  8. Monk B J, Tewari KS, Wui-Jin Koh: Multimodality therapy for locally advanced cervical carcinoma: state of the art and future directions. J Clin Oncol 25: 2952–2965, 2007.

    Article  PubMed  CAS  Google Scholar 

  9. Petereit DG, Pearcey R: Literature analysis of high dose rate brachytherapy fractionation schedules in the treatment of cervical cancer: Is there an optimal fractionation schedule? Int J Radiat Oncol Biol Phys 43:359–366, 1999.

    Article  PubMed  CAS  Google Scholar 

  10. Mai J, Erickson B, Rownd J, et al: Comparison of four different dose specification methods for high-dose-rate Intracavitary radiation for treatment of cervical cancer. Int J Radiat Oncol Biol Phys 51:1131–1141, 2001.

    Article  PubMed  CAS  Google Scholar 

  11. Vistad I, Fossa SD, Dahl AA: A critical review of patientrated quality of life studies of long-term survivors of cervical cancer: Gynecol Oncol 102:563–573, 2006.

    Article  PubMed  Google Scholar 

  12. Wenzel L, DeAlba I, Habal R, et al: Quality of life in longterm cervical cancer survivors. Gynecol Oncol 97:310–317, 2005.

    Article  PubMed  Google Scholar 

  13. Stephens FO, Why use regional chemotherapy? Principles ande Pharmacokinetics. Reg Cancer Treat 1: 4–10, 1988.

    Google Scholar 

  14. Villena-Heinsen C, Mink D, Lung-Kurt S, et al: Preoperative intraarterial chemotherapy for bulky cervical carcinoma in stage Ib – IIb. Reg Cancer Treat 1:17–21, 1994.

    Google Scholar 

  15. Scarabelli C, Zarrelli A, Gallo A, et al: Pelvic recurrences in cervical cancer : multimodal treatment with sequential intra-arterial chemotherapy and surgery. Reg Cancer Treat 1:12–16, 1994.

    Google Scholar 

  16. de Dycker RP: Pelvic arterial chemotherapy in cervical cancer. Reg Cancer Treat 7:43–46, 1994.

    Google Scholar 

  17. Aigner KR, Gailhofer S: 6 years disease free survival after isolated hypoxic pelvic perfusion with chemofiltration for advanced cervical carcinoma. J Nucl Med Radiat Ther 2012 S2:007. DOI:1.S2–007

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Aigner, K.R., Jansa, J. (2013). Induktionschemotherapie bei Tumoren des Beckens – das Zervixkarzinom. In: Aigner, K.R., Stephens, F.O., Vogl, T.J., Padberg, W. (eds) Regionale Therapie maligner Tumoren. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35014-6_21

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-35014-6_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-35013-9

  • Online ISBN: 978-3-642-35014-6

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics