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Biomarkers in Neoplastic Neuropathology

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Abstract

One of the main advantages of cancer research and the field of biomarker discovery is the public availability of high-throughput data on an unparalleled scale. This has been made possible by the availability of public, user-friendly databases that allow the mining of large molecular datasets with ease. The Cancer Genome Atlas (TCGA) effort, pioneered in the study of brain cancer (glioblastoma), has also become a priceless resource for neoplastic neuropathology and has fueled numerous efforts in the generation and testing of specific hypotheses and biomarker discovery. Currently, TCGA has completed comprehensive molecular profiling of glioblastomas and lower-grade gliomas (diffuse gliomas grades II–III), the most important group of primary brain tumors in adults.

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Authors and Affiliations

  1. Pathology, Johns Hopkins University, Baltimore, Maryland, USA

    Fausto Rodriguez

  2. Pathology, Children’s National Medical Center, Washington, D.C., District of Columbia, USA

    Cheng-Ying Ho

Authors
  1. Fausto Rodriguez
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  2. Cheng-Ying Ho
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© 2016 Springer International Publishing Switzerland

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Rodriguez, F., Ho, CY. (2016). Public Databases. In: Biomarkers in Neoplastic Neuropathology. Springer, Cham. https://doi.org/10.1007/978-3-319-20931-9_4

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  • DOI: https://doi.org/10.1007/978-3-319-20931-9_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-20930-2

  • Online ISBN: 978-3-319-20931-9

  • eBook Packages: MedicineMedicine (R0)

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