Experimental Part

Abstract

All chemicals were commercially available, purchased from sigma Aldrich and used without further purification unless otherwise stated. Methyl methacrylate (MMA), 2-hydroxyethyl methacrylate (HEMA) diethylenegylcol dimethacrylate (DEGDMA) and divinyl benzene (DVB) were purified over basic aluminium oxide to remove contained inhibitor. Methacrylic acid (MAA), triethylamine and 2,4-toluenediisocyanate (TDI) were distilled under reduced pressure prior to use. Acrylamide was obtained from Fluka Chemicals. Doxorubicin Hydrochloride was obtained from AppliChem. Initiators (2,2′-azobis(2-methyl-butyronitrile) (V-59); 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile) (V-70); 2,2′-azobis(N,N′-dimethyleneiso-butyramidine) dihydro-chloride (VA-044)) were obtained from Wako Chemicals. Lubrizol U (poly(isobutylene-succinimde pentamine)) was kindly provided by Lubrizol, France. Poly(ethylene-co-butylene)-block-poly(ethyleneglycol) [P(E/B)-b-PEO, KLE] [M _n(P(E/B) = 5,800 g/mol; M _n(PEO) = 6,200 g/mol] was prepared by anionic polymerization by Melanie Droege. Lutensol AT-50 was kindly provided by BASF.