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Inducibility of Metabolizing Enzymes

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Activation and Detoxification Enzymes

Abstract

Metabolic enzyme inducibility is of major significance, because it plays an important role in the susceptibility of individuals to foreign compound–mediated toxicities. Although some xenobiotics exhibit intrinsic toxicity, while some others are metabolically activated to potential toxicants by activation enzymes. The generated metabolites undergo detoxification enzyme–catalyzed reactions for detoxification, before foreign compounds are ready for excretion.

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Authors and Affiliations

  1. Institute for Health, and the Environment and Department of Biomedical Sciences, University at Albany, State University of New York, Albany, NY, USA

    Chang-Hwei Chen

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  1. Chang-Hwei Chen
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Chen, CH. (2024). Inducibility of Metabolizing Enzymes. In: Activation and Detoxification Enzymes. Springer, Cham. https://doi.org/10.1007/978-3-031-55287-8_15

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